Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression

scientific article published on 21 April 2008

Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20071698
P932PMC publication ID2373844
P698PubMed publication ID18426984
P5875ResearchGate publication ID5425868

P50authorBrice SperandioQ58314751
P2093author name stringPhilippe J Sansonetti
Zhi Zhang
Béatrice Regnault
Jianhua Guo
Samuel L Stanley
Thierry Pédron
P2860cites workBeta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6Q22010648
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Defensins: antimicrobial peptides of innate immunityQ28204453
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Host-pathogen interactions: subversion and utilization of the NF-kappa B pathway during infectionQ28386446
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?Q29547675
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Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.Q29871487
Local-pooled-error test for identifying differentially expressed genes with a small number of replicated microarraysQ30311902
Emerging patterns and gene expression data.Q30670078
Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulationQ33274199
Molecular bases of epithelial cell invasion by Shigella flexneriQ33542385
Regulation of dendritic cell trafficking: a process that involves the participation of selective chemokinesQ33712280
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymesQ34048081
Intestinal IgA synthesis: regulation of front-line body defencesQ34168492
Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibioticQ34694936
Enteric salmonella infection inhibits Paneth cell antimicrobial peptide expressionQ34716119
Rapid assessment of antibiotic effects on Escherichia coli by bis-(1,3-dibutylbarbituric acid) trimethine oxonol and flow cytometry.Q35138198
Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytesQ35220350
Human intestinal epithelial cells produce proinflammatory cytokines in response to infection in a SCID mouse-human intestinal xenograft model of amebiasis.Q35546207
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Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosisQ36363758
Involvement of a plasmid in the invasive ability of Shigella flexneri.Q36437346
The co-evolution of host cationic antimicrobial peptides and microbial resistanceQ36508686
Nod-like proteins in immunity, inflammation and diseaseQ36655897
Debugging how bacteria manipulate the immune response.Q36739044
Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosaQ36813569
Structure and function of the intestinal epithelial barrier in health and diseaseQ38142953
NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium.Q40017434
The phosphothreonine lyase activity of a bacterial type III effector familyQ40170436
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responsesQ40198172
Neisseria gonorrhoeae downregulates expression of the human antimicrobial peptide LL-37.Q40410408
Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosisQ40426449
Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domainQ40432691
Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB.Q40538294
Differential expression of sucrase-isomaltase in clones isolated from early and late passages of the cell line Caco-2: evidence for glucose-dependent negative regulationQ41498843
MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasinsQ41504166
Shigella flexneri induces apoptosis in infected macrophagesQ41614246
Differential regulation of beta-defensin expression in human skin by microbial stimuliQ44742019
SepA, the 110 kDa protein secreted by Shigella flexneri: two-domain structure and proteolytic activityQ47721067
Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defenseQ47922120
Type III secretion effectors of the IpaH family are E3 ubiquitin ligasesQ50066742
The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2.Q52952279
Regulation of transcription by the activity of the Shigella flexneri type III secretion apparatus.Q54546861
Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulatorQ57940216
The host-pathogen interaction: new themes from dendritic cell biologyQ74386851
Analysis of virulence plasmid gene expression defines three classes of effectors in the type III secretion system of Shigella flexneriQ81503204
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectantimicrobial peptideQ1201508
Shigella flexneriQ1644417
P304page(s)1121-1132
P577publication date2008-04-21
P1433published inJournal of Experimental MedicineQ3186912
P1476titleVirulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression
P478volume205

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