| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2010PLoSO...512356M |
| P356 | DOI | 10.1371/JOURNAL.PONE.0012356 |
| P932 | PMC publication ID | 2932980 |
| P698 | PubMed publication ID | 20827300 |
| P5875 | ResearchGate publication ID | 253107009 |
| P50 | author | Charalampos Rallis | Q42061204 |
| P2093 | author name string | Leonard J Foster | |
| Jun Yan | |||
| David Ish-Horowicz | |||
| Gregory E Hannigan | |||
| Jasbinder Sanghera | |||
| Michael P Walsh | |||
| Mykola Maydan | |||
| Paul C McDonald | |||
| Sheena Pinchin | |||
| Shoukat Dedhar | |||
| P2860 | cites work | Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase | Q24314398 |
| CASK Functions as a Mg2+-independent neurexin kinase | Q24323323 | ||
| Integrin-linked kinase phosphorylates the myosin phosphatase target subunit at the inhibitory site in platelet cytoskeleton | Q24534169 | ||
| ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation | Q24621754 | ||
| Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitors | Q24644388 | ||
| Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization | Q24655829 | ||
| A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction | Q24679147 | ||
| Phosphorylation of protein phosphatase type-1 inhibitory proteins by integrin-linked kinase and cyclic nucleotide-dependent protein kinases | Q57445929 | ||
| Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival | Q40333076 | ||
| Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway | Q40420070 | ||
| Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth. | Q40443893 | ||
| Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation | Q40657196 | ||
| Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase | Q41827565 | ||
| Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure | Q41866389 | ||
| Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway | Q42138548 | ||
| Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart | Q42850406 | ||
| Differential effects of divalent manganese and magnesium on the kinase activity of leucine-rich repeat kinase 2 (LRRK2). | Q43141823 | ||
| Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. | Q43796891 | ||
| Regulation of tumor angiogenesis by integrin-linked kinase (ILK). | Q44746334 | ||
| Integrin-linked kinase regulates the nuclear entry of the c-Jun coactivator alpha-NAC and its coactivation potency | Q45010284 | ||
| RGD peptides confer survival to hepatocytes via the beta1-integrin-ILK-pAkt pathway | Q45209569 | ||
| Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xe | Q45285589 | ||
| Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. | Q45986472 | ||
| Mapping of calmodulin-binding domain of Ca2+/calmodulin-dependent protein kinase II from rat brain | Q48088192 | ||
| Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase | Q24682825 | ||
| The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions | Q27646573 | ||
| Structure and functional characterization of the atypical human kinase haspin | Q27658205 | ||
| Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification | Q28131753 | ||
| Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343 | Q28213632 | ||
| Integrin-linked kinase is an adaptor with essential functions during mouse development | Q28261429 | ||
| Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair | Q28295270 | ||
| An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth | Q28564696 | ||
| Phosphorylation of the myosin phosphatase inhibitors, CPI-17 and PHI-1, by integrin-linked kinase | Q28570031 | ||
| Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways | Q28571378 | ||
| Role of the integrin-linked kinase (ILK) in determining neuronal polarity | Q28572867 | ||
| NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC | Q28586090 | ||
| Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis | Q28589224 | ||
| Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase | Q30661698 | ||
| The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! | Q33668166 | ||
| Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. | Q33762935 | ||
| Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5)beta(1) integrin-mediated pathway | Q33896998 | ||
| The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. | Q33911629 | ||
| Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner | Q33959947 | ||
| Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival | Q34230960 | ||
| Blue silver: a very sensitive colloidal Coomassie G-250 staining for proteome analysis | Q34324172 | ||
| Kinetic and catalytic mechanisms of protein kinases | Q34465987 | ||
| Emerging roles of pseudokinases | Q34552850 | ||
| Rethinking pseudokinases | Q34590810 | ||
| Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation | Q36364880 | ||
| Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane | Q36379951 | ||
| ILK, PINCH and parvin: the tIPP of integrin signalling | Q36403372 | ||
| Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage | Q36491774 | ||
| Integrin-linked kinase--essential roles in physiology and cancer biology. | Q37272385 | ||
| Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells | Q38299785 | ||
| Integrin-linked kinase is an essential mediator for T-cadherin-dependent signaling via Akt and GSK3beta in endothelial cells | Q40135983 | ||
| Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck | Q40182975 | ||
| R-Ras controls axon specification upstream of glycogen synthase kinase-3beta through integrin-linked kinase | Q40208190 | ||
| Novel role for integrin-linked kinase in modulation of coxsackievirus B3 replication and virus-induced cardiomyocyte injury | Q40255909 | ||
| Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells | Q40262829 | ||
| Quantitative comparison of caste differences in honeybee hemolymph | Q40295910 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | e12356 | |
| P577 | publication date | 2010-08-23 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation | |
| P478 | volume | 5 |
| Q35956150 | Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells |
| Q35065294 | Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase. |
| Q35903772 | Cellular and molecular mechanisms of renal fibrosis |
| Q38122228 | Dawn of the dead: protein pseudokinases signal new adventures in cell biology |
| Q35640263 | Elevated PI3K signaling drives multiple breast cancer subtypes |
| Q38689489 | Enhanced Ca2+Entry and Tyrosine Phosphorylation Mediate Nanostructure-Induced Endothelial Proliferation. |
| Q42246015 | Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression |
| Q57051343 | Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia |
| Q47680353 | IL7RA haplotype-associated alterations in cellular immune function and gene expression patterns in multiple sclerosis. |
| Q27001701 | ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling |
| Q36202719 | Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival |
| Q27315213 | Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae |
| Q37528252 | Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. |
| Q37733714 | Insights into the Structure, Function, and Ion-Mediated Signaling Pathways Transduced by Plant Integrin-Linked Kinases. |
| Q92969956 | Insulin attenuates apoptosis in neuronal cells by an integrin-linked kinase-dependent mechanism |
| Q28299126 | Integrin signalling adaptors: not only figurants in the cancer story |
| Q38748841 | Integrin-Linked Kinase Regulates Bone Formation by Controlling Cytoskeletal Organization and Modulating BMP and Wnt Signaling in Osteoprogenitors. |
| Q50993502 | Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease. |
| Q44121201 | Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF). |
| Q42025988 | Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. |
| Q42357572 | Integrin-linked kinase in ciliary Hedgehog signaling |
| Q47816202 | Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function |
| Q34283506 | Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation |
| Q36772600 | Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-κB signaling in colorectal cancer cells |
| Q27321017 | Integrin-linked kinase regulates interphase and mitotic microtubule dynamics |
| Q42727619 | Integrin-linked kinase: a Scaffold protein unique among its ilk. |
| Q37878251 | Integrin-linked kinase: not so 'pseudo' after all. |
| Q24310715 | Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling |
| Q30588724 | LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase |
| Q35987858 | LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration. |
| Q46309597 | Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders |
| Q33997601 | Motility, survival, and proliferation |
| Q41905980 | Myosin regulatory light chain diphosphorylation slows relaxation of arterial smooth muscle |
| Q30503120 | PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling. |
| Q35628583 | RNA silencing of integrin-linked kinase increases the sensitivity of the A549 lung cancer cell line to cisplatin and promotes its apoptosis |
| Q34182228 | Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival. |
| Q60601167 | Selective regulation of p38β protein and signaling by integrin-linked kinase mediates bladder cancer cell migration |
| Q38122229 | Techniques to examine nucleotide binding by pseudokinases |
| Q34527703 | The Raf-like Kinase ILK1 and the High Affinity K+ Transporter HAK5 Are Required for Innate Immunity and Abiotic Stress Response. |
| Q34118683 | The function of integrin-linked kinase in normal and activated stellate cells: implications for fibrogenesis in wound healing |
| Q97525008 | Therapeutic effect of integrin-linked kinase gene-modified bone marrow-derived mesenchymal stem cells for streptozotocin-induced diabetic cystopathy in a rat model |
| Q36720975 | Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model |
| Q37944602 | Vascular smooth muscle myosin light chain diphosphorylation: mechanism, function, and pathological implications |
| Q28250984 | Versican in inflammation and tissue remodeling: the impact on lung disorders |
| Q38915530 | Wnt/β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cells |
| Q35312201 | mda-9/Syntenin protein positively regulates the activation of Akt protein by facilitating integrin-linked kinase adaptor function during adhesion to type I collagen |
| Q35080919 | β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny |
| Q98158668 | β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells |
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