| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Hugo A. Katus | Q27929168 |
| P2093 | author name string | Steffen Just | |
| Wolfgang Rottbauer | |||
| Inken G Huttner | |||
| Mark C Fishman | |||
| Garnet Bendig | |||
| Georgia Wessels | |||
| Matthias Grimmler | |||
| Nicole Trano | |||
| Tillman Dahme | |||
| P2860 | cites work | Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats | Q22010842 |
| Cardiac troponin T is essential in sarcomere assembly and cardiac contractility | Q46049216 | ||
| The zebrafish as a model system to study cardiovascular development | Q46498108 | ||
| Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin | Q47073224 | ||
| Nanospring behaviour of ankyrin repeats. | Q51286970 | ||
| Effects of growth hormone on cardiac dysfunction and gene expression in genetic murine dilated cardiomyopathy. | Q52542229 | ||
| Regulation of fibronectin matrix deposition and cell proliferation by the PINCH-ILK-CH-ILKBP complex | Q64378764 | ||
| Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes | Q72409853 | ||
| Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo | Q73010073 | ||
| The Akt-glycogen synthase kinase 3beta pathway regulates transcription of atrial natriuretic factor induced by beta-adrenergic receptor stimulation in cardiac myocytes | Q73754958 | ||
| Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis | Q77114860 | ||
| A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration | Q77123038 | ||
| Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes | Q77807872 | ||
| Pulsatile stretch stimulates vascular endothelial growth factor (VEGF) secretion by cultured rat cardiac myocytes | Q77906028 | ||
| Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase | Q24314398 | ||
| A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction | Q24679147 | ||
| Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase | Q24682825 | ||
| Cell-substrate interactions and signaling through ILK | Q28138260 | ||
| Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343 | Q28213632 | ||
| Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart | Q28249388 | ||
| Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair | Q28295270 | ||
| Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells | Q28344025 | ||
| Disruption of integrin function in the murine myocardium leads to perinatal lethality, fibrosis, and abnormal cardiac performance | Q28359740 | ||
| Integrin-linked kinase is a positive mediator of L6 myoblast differentiation | Q28567387 | ||
| Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways | Q28571378 | ||
| Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo | Q28578411 | ||
| Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation | Q28585627 | ||
| Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit | Q31029431 | ||
| Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. | Q33762935 | ||
| Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes | Q34429805 | ||
| Costameres, focal adhesions, and cardiomyocyte mechanotransduction. | Q36311725 | ||
| CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt | Q36323145 | ||
| Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation | Q36364880 | ||
| Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane | Q36379951 | ||
| ILK, PINCH and parvin: the tIPP of integrin signalling | Q36403372 | ||
| Integrin-linked kinase regulates endothelial cell survival and vascular development. | Q37493087 | ||
| Identification of markers linked to disease-resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations | Q37614439 | ||
| Ontogeny of cardiovascular and respiratory physiology in lower vertebrates | Q37739393 | ||
| Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway | Q40420070 | ||
| Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway | Q42162154 | ||
| Cardiac overexpression of melusin protects from dilated cardiomyopathy due to long-standing pressure overload. | Q42477557 | ||
| Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure | Q42518393 | ||
| VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart | Q42915525 | ||
| Endogenous nitric oxide mechanisms mediate the stretch dependence of Ca2+ release in cardiomyocytes | Q43754940 | ||
| C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes | Q43996515 | ||
| Dissection of angiogenic signaling in zebrafish using a chemical genetic approach | Q44043150 | ||
| Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. | Q44237320 | ||
| Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload | Q44259257 | ||
| Regulation of tumor angiogenesis by integrin-linked kinase (ILK). | Q44746334 | ||
| P433 | issue | 17 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Danio rerio | Q169444 |
| Integrin-linked kinase | Q29834567 | ||
| P304 | page(s) | 2361-2372 | |
| P577 | publication date | 2006-08-18 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart | |
| P478 | volume | 20 |
| Q58752907 | A Langendorff-like system to quantify cardiac pump function in adult zebrafish |
| Q41144341 | A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion |
| Q37018675 | A novel mechanism of mechanical stress-induced angiotensin II type 1-receptor activation without the involvement of angiotensin II. |
| Q64114745 | A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo |
| Q42639922 | Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy |
| Q83372560 | Affixin (β-parvin) promotes cardioprotective signaling via STAT3 activation |
| Q51896662 | AhR2-mediated, CYP1A-independent cardiovascular toxicity in zebrafish (Danio rerio) embryos exposed to retene |
| Q28588987 | Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling |
| Q38832827 | Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins. |
| Q26865437 | Animal and in silico models for the study of sarcomeric cardiomyopathies |
| Q45986472 | Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. |
| Q35065294 | Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase. |
| Q34160361 | Cardiac Z-disc signaling network |
| Q30438289 | Cell adhesion receptors in mechanotransduction |
| Q27304878 | Corresponding morphological and molecular indicators of crude oil toxicity to the developing hearts of mahi mahi |
| Q37631255 | Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice |
| Q36202892 | Deletion of integrin-linked kinase from skeletal muscles of mice resembles muscular dystrophy due to alpha 7 beta 1-integrin deficiency |
| Q30490809 | Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere-membrane interaction, not sarcomere assembly |
| Q44590642 | Dilated cardiomyopathy as a genetic disease: molecular and clinical aspects |
| Q36029873 | Dynamic expression patterns of leucine-rich repeat containing protein 10 in the heart |
| Q64376741 | Effect of transplantation of cardiac stem cells overexpressing integrin-linked kinase on cardiac function of rats with acute myocardial infarction |
| Q45309205 | Effects of integrin-linked kinase on human corpus cavernosum smooth muscle cell cytoskeletal organisation |
| Q30564783 | Engineering the heart: evaluation of conductive nanomaterials for improving implant integration and cardiac function |
| Q39382663 | Epigenetics, inflammation and metabolism in right heart failure associated with pulmonary hypertension |
| Q37133680 | Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction |
| Q37365207 | Fishing for the genetic basis of cardiovascular disease. |
| Q54262938 | Focal Adhesion Proteins α- and β-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression. |
| Q37406670 | Focal adhesion: a focal point in current cell biology and molecular medicine |
| Q38235819 | From stem cells to cardiomyocytes: the role of forces in cardiac maturation, aging, and disease. |
| Q97517249 | Genetic Animal Models for Arrhythmogenic Cardiomyopathy |
| Q38024282 | Genetic cardiomyopathies. Lessons learned from humans, mice, and zebrafish |
| Q27691994 | Genetics and disease of ventricular muscle |
| Q55137371 | Genetics of Cardiovascular Disease: Fishing for Causality. |
| Q37375934 | Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides |
| Q34440155 | High-throughput screening of zebrafish embryos using automated heart detection and imaging |
| Q34292636 | ILK induces cardiomyogenesis in the human heart |
| Q60915245 | Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth |
| Q34163462 | Increased expression of integrin-linked kinase improves cardiac function and decreases mortality in dilated cardiomyopathy model of rats |
| Q28749480 | Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation |
| Q24655829 | Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization |
| Q47816202 | Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function |
| Q36491774 | Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage |
| Q37878251 | Integrin-linked kinase: not so 'pseudo' after all. |
| Q34992704 | Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish |
| Q37420377 | Loss of the AE3 Cl(-)/HCO(-) 3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart |
| Q30480329 | Lrrc10 is required for early heart development and function in zebrafish |
| Q28834419 | Mechanical dynamics in live cells and fluorescence-based force/tension sensors |
| Q52591110 | Mechanisms of Cardiac Repair and Regeneration. |
| Q34632608 | Mechanosensing and Regulation of Cardiac Function |
| Q38619878 | Mechanosensitivity of integrin adhesion complexes: role of the consensus adhesome |
| Q37866169 | Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function |
| Q41692598 | Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish |
| Q37481044 | Molecular mechanisms of mechanosensing in muscle development. |
| Q102317809 | Morpho-functional remodelling of the adult zebrafish (Danio rerio) heart in response to waterborne angiotensin II exposure |
| Q35048027 | Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex |
| Q88641621 | Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish |
| Q64012839 | Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy |
| Q52560637 | New perspectives: systems medicine in cardiovascular disease. |
| Q24313460 | Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy |
| Q37799097 | Novel aspects of angiotensin II action in the heart. Implications to myocardial ischemia and heart failure |
| Q27967980 | Novel protein-protein interactions inferred from literature context |
| Q30505441 | Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish |
| Q30503120 | PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling. |
| Q27319877 | Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart |
| Q38570775 | Recent progress in the use of zebrafish for novel cardiac drug discovery |
| Q27325403 | Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart |
| Q33346399 | Right into the heart of microRNA-133a |
| Q37608582 | Role of the sarcomeric Z-disc in the pathogenesis of cardiomyopathy |
| Q60937837 | Semantic Multi-Classifier Systems Identify Predictive Processes in Heart Failure Models across Species |
| Q46548247 | Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1. |
| Q33916456 | Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy |
| Q35211167 | Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis. |
| Q34319557 | Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. |
| Q36299864 | Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish |
| Q33668166 | The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! |
| Q42711137 | The Load-Bearing Mechanosome Revisited |
| Q47071450 | The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link |
| Q38321714 | The many faces of cell adhesion during Drosophila muscle development |
| Q37659191 | The zebrafish model system in cardiovascular research: A tiny fish with mighty prospects |
| Q93275066 | Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish |
| Q37607128 | Thrombospondins in the heart: potential functions in cardiac remodeling |
| Q38043058 | Uncovering the molecular and cellular mechanisms of heart development using the zebrafish. |
| Q37563953 | Vascular dysfunction in idiopathic dilated cardiomyopathy. |
| Q40574936 | Zebrafish as a model for cardiovascular development and disease |
| Q37878169 | Zebrafish as a model to study cardiac development and human cardiac disease |
| Q34774115 | Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex |
| Q38019209 | Zebrafish models in cardiac development and congenital heart birth defects |
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