Uncovering the molecular and cellular mechanisms of heart development using the zebrafish.

scientific article published on 04 September 2012

Uncovering the molecular and cellular mechanisms of heart development using the zebrafish. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV-GENET-110711-155646
P932PMC publication ID6982417
P698PubMed publication ID22974299

P50authorDavid StaudtQ60311772
Didier StainierQ36832398
P2093author name stringDavid Staudt
P2860cites workNexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathyQ24313460
Dominant-negative ALK2 allele associates with congenital heart defectsQ24337521
Zinc finger-based knockout punches for zebrafish genesQ24604726
Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca(2+) channelQ24632619
Early myocardial function affects endocardial cushion development in zebrafishQ24796758
Early endocardial morphogenesis requires Scl/Tal1Q27314921
Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heartQ27325403
Genetic and physiologic dissection of the vertebrate cardiac conduction systemQ27333494
Functional modulation of cardiac form through regionally confined cell shape changesQ27334821
Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathwayQ28116174
Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heartQ28249388
Apelin and its receptor control heart field formation during zebrafish gastrulationQ28291376
The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitorsQ28291389
Chamber formation and morphogenesis in the developing mammalian heartQ28566310
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformationQ28589469
A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesisQ28594073
Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafishQ28751283
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectinQ29617865
Heart regeneration in zebrafishQ29619776
Zebrafish model for human long QT syndromeQ30480271
Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heartQ30487250
Extra-embryonic syndecan 2 regulates organ primordia migration and fibrillogenesis throughout the zebrafish embryoQ30489674
Joint dynamic imaging of morphogenesis and function in the developing heartQ30494734
CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformationsQ30495754
Cardiac conduction is required to preserve cardiac chamber morphologyQ30496345
A dual role for ErbB2 signaling in cardiac trabeculationQ30498335
Chromatin remodelling complex dosage modulates transcription factor function in heart developmentQ30500285
heart of glass regulates the concentric growth of the heart in zebrafish.Q44696937
Zebrafish mosaic eyes is a novel FERM protein required for retinal lamination and retinal pigmented epithelial tight junction formationQ44844573
Organization of cardiac chamber progenitors in the zebrafish blastulaQ44919400
Retinoic acid signaling restricts the cardiac progenitor poolQ45226471
Fibronectin regulates epithelial organization during myocardial migration in zebrafish.Q45954816
Cardiac troponin T is essential in sarcomere assembly and cardiac contractilityQ46049216
A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivoQ46147959
High-speed imaging of developing heart valves reveals interplay of morphogenesis and function.Q46219006
Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesisQ46606862
Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.Q46771674
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve developmentQ46777246
Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5.Q46789328
Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus heartsQ46802509
Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesisQ46828689
In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongationQ46952858
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titinQ47073224
Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion developmentQ47073246
santa and valentine pattern concentric growth of cardiac myocardium in the zebrafishQ47073296
Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafishQ47073414
Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular diseaseQ47073658
The Wnt/beta-catenin pathway regulates cardiac valve formationQ47073676
In-vivo characterization of human dilated cardiomyopathy genes in zebrafishQ47073689
Mutations affecting the cardiovascular system and other internal organs in zebrafishQ47073714
The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish.Q47073744
A zebrafish model of human Barth syndrome reveals the essential role of tafazzin in cardiac development and functionQ47073745
Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cellsQ47073904
Dependence of cardiac trabeculation on neuregulin signaling and blood flow in zebrafishQ47073947
Endocardium is necessary for cardiomyocyte movement during heart tube assemblyQ47074005
Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 ActivityQ47074088
Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafishQ47074114
Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafishQ50524443
Patterning the zebrafish heart tube: acquisition of anteroposterior polarityQ51148857
Asymmetric involution of the myocardial field drives heart tube formation in zebrafishQ51966942
Notch1b and neuregulin are required for specification of central cardiac conduction tissueQ52025862
Developmental transitions in electrical activation patterns in chick embryonic heartQ52087560
Structure and function of the developing zebrafish heartQ52165184
Localization of pacemaking activity in early embryonic heart monitored using voltage-sensitive dye.Q52293882
Heritable gene targeting in zebrafish using customized TALENsQ55054727
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryoQ73010073
Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soulQ74601216
Understanding conduction system development: a hop, skip and jump away?Q81698666
Cardiac performance in the zebrafish breakdance mutantQ81782039
Screening: the age of fishesQ83060013
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.Q30502828
The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin developmentQ30872704
Growth and Function of the Embryonic Heart Depend upon the Cardiac-Specific L-Type Calcium Channel α1 SubunitQ31029431
Genetics of cavernous angiomasQ31101050
The embryonic vertebrate heart tube is a dynamic suction pumpQ33242339
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafishQ33292068
Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryosQ33401587
High-throughput in vivo vertebrate screeningQ33635305
Optogenetic control of cardiac functionQ33744875
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferationQ33757338
The zebrafish heart regenerates after cryoinjury-induced myocardial infarction.Q33865216
Gata5 is required for the development of the heart and endoderm in zebrafish.Q33882061
Regeneration of cryoinjury induced necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte proliferationQ33886873
Reverse genetics in zebrafish by TILLING.Q33974209
Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin functionQ34107608
The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesisQ34114731
Calcium handling in zebrafish ventricular myocytesQ34142132
Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages.Q34297652
Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potentialQ34421441
Making or breaking the heart: from lineage determination to morphogenesisQ34567781
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.Q34618217
Controlling morpholino experiments: don't stop making antisense.Q34769101
The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursorsQ34901297
Zebrafish cardiac development requires a conserved secondary heart fieldQ34966448
Cardiac development in zebrafish: coordination of form and functionQ35018089
The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursorsQ35193894
The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis.Q35208712
Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 functionQ35306055
Vertebrate organogenesis: getting the heart into shapeQ35694172
Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cellsQ35808417
Illuminating cardiac development: Advances in imaging add new dimensions to the utility of zebrafish geneticsQ35809279
Latent TGF-β binding protein 3 identifies a second heart field in zebrafishQ35869406
Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytesQ36319329
Getting to the heart of regeneration in zebrafish.Q36687815
Visualization and functional characterization of the developing murine cardiac conduction systemQ36778773
Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionalityQ37258930
Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanismsQ37300161
Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell numberQ37362967
Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heartQ37362971
Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarizationQ37407596
Shaping the zebrafish heart: from left-right axis specification to epithelial tissue morphogenesisQ37446131
Zebrafish as a model to study cardiac development and human cardiac diseaseQ37878169
Foxn4 directly regulates tbx2b expression and atrioventricular canal formationQ38292640
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cellsQ38299785
Hand2 regulates epithelial formation during myocardial diferentiation.Q38328945
Restraint of Fgf8 signaling by retinoic acid signaling is required for proper heart and forelimb formationQ38381398
Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryoQ39734092
Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 proteinQ39860393
Distinct phases of Wnt/β-catenin signaling direct cardiomyocyte formation in zebrafishQ40004247
Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish.Q40222814
Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish.Q40797201
Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterningQ40855804
Cardiovascular development in the zebrafish. II. Endocardial progenitors are sequestered within the heart fieldQ41010973
Cardiovascular development in the zebrafish. I. Myocardial fate map and heart tube formationQ41068431
casanova plays an early and essential role in endoderm formation in zebrafishQ41699814
A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart developmentQ41750054
Redundancy and evolution of GATA factor requirements in development of the myocardiumQ41790172
oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo.Q42495698
The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish.Q42551908
Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heartQ42850406
Targeted gene disruption in somatic zebrafish cells using engineered TALENsQ42862072
VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heartQ42915525
Vessel and blood specification override cardiac potential in anterior mesodermQ43095435
Regulation of neurocoel morphogenesis by Pard6 gamma b.Q43198871
UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish.Q43726666
nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retinaQ43981047
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesisQ43998282
The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome.Q44132465
Reptin and pontin antagonistically regulate heart growth in zebrafish embryos.Q44237320
P921main subjectDanio rerioQ169444
P304page(s)397-418
P577publication date2012-09-04
P1433published inAnnual Review of GeneticsQ567358
P1476titleUncovering the molecular and cellular mechanisms of heart development using the zebrafish
P478volume46

Reverse relations

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