Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion

scientific article published on 04 August 2020

Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FCELL.2020.00738
P932PMC publication ID7417483
P698PubMed publication ID32850848

P2093author name stringWufan Tao
Tao P Zhong
Yabo Fang
Jianjian Sun
Peilu She
Kaa Seng Lai
P2860cites workMutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathyQ24324422
Mammalian heart renewal by pre-existing cardiomyocytesQ24632538
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte functionQ24634382
Targeting BMP signalling in cardiovascular disease and anaemiaQ26783734
Mending broken hearts: cardiac development as a basis for adult heart regeneration and repairQ26852506
Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling.Q27316878
A new class of small molecule inhibitor of BMP signalingQ27678000
Development of the endocardiumQ27692614
N-cadherin/catenin complex as a master regulator of intercalated disc functionQ28238884
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterningQ28504579
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptationQ28507763
Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2Q28513329
The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesisQ28587449
Immune responses in cardiac repair and regeneration: a comparative point of viewQ90712264
Reassessment of c-Kit+ Cells for Cardiomyocyte Contribution in Adult HeartQ91706502
Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repairQ92701459
Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafishQ50524443
Transgenesis in zebrafish with the tol2 transposon systemQ50591662
High-throughput assay for small molecules that modulate zebrafish embryonic heart rateQ50743158
MAPK/ERK signalling is required for zebrafish cardiac regenerationQ50941230
ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferationQ50992137
A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regenerationQ52002879
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac RegenerationQ52729011
Blood flow and Bmp signaling control endocardial chamber morphogenesisQ52874313
The Janus face of OSM-mediated cardiomyocyte dedifferentiation during cardiac repair and diseaseQ53190951
Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart.Q55238585
A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to humanQ57471960
Profiling proliferative cells and their progeny in damaged murine heartsQ60911613
Endocardial Notch Signaling Promotes Cardiomyocyte Proliferation in the Regenerating Zebrafish Heart through Wnt Pathway AntagonismQ61816623
The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomicsQ64260967
Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodelingQ82360998
Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte RegenerationQ87045099
Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial DevelopmentQ89107305
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesisQ28592753
A palette of fluorescent proteins optimized for diverse cellular environmentsQ28647200
Heart regeneration in zebrafishQ29619776
Transient regenerative potential of the neonatal mouse heartQ29620371
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.Q30502828
TBX20 loss-of-function mutation responsible for familial tetralogy of Fallot or sporadic persistent truncus arteriosusQ33702965
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferationQ33757338
PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish heartsQ34182901
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and functionQ34253862
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.Q34618217
Cardiac regenerative capacity and mechanismsQ34643788
Myocardium and BMP signaling are required for endocardial differentiationQ35877477
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart.Q36602112
Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction.Q36689735
Modulation of tissue repair by regeneration enhancer elementsQ36832920
Fast revascularization of the injured area is essential to support zebrafish heart regenerationQ37323217
Hippo signaling impedes adult heart regeneration.Q37323625
Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesisQ37597645
Mechanisms of T-box gene function in the developing heartQ37865969
Uncovering the molecular and cellular mechanisms of heart development using the zebrafish.Q38043058
Regulation of fetal gene expression in heart failureQ38137629
Regeneration across metazoan phylogeny: lessons from model organismsQ38361869
Cardiac regeneration strategies: Staying young at heart.Q39360699
Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafishQ42027279
Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regenerationQ42050363
Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expressionQ42132732
tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regenerationQ42766102
Tbx20 promotes cardiomyocyte proliferation and persistence of fetal characteristics in adult mouse heartsQ43640618
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatusQ44364076
Cellular and molecular analyses of vascular tube and lumen formation in zebrafish.Q46349781
Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafishQ46447680
Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafishQ47073519
Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafishQ47073737
Expression of tbx20 RNA during chick heart developmentQ47367846
Structure and function of the Nppa-Nppb cluster locus during heart development and diseaseQ47882562
Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heartQ48189185
Dedifferentiation, Proliferation, and Redifferentiation of Adult Mammalian Cardiomyocytes After Ischemic InjuryQ50198230
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)738
P577publication date2020-08-04
P1433published inFrontiers in Cell and Developmental BiologyQ27725488
P1476titleTbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion
P478volume8

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