Zebrafish: A marvel of high-throughput biology for 21(st) century toxicology.

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Zebrafish: A marvel of high-throughput biology for 21(st) century toxicology. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1010917569
P356DOI10.1007/S40572-014-0029-5
P932PMC publication ID4321749
P698PubMed publication ID25678986
P5875ResearchGate publication ID267159244

P50authorRobyn L TanguayQ47144867
Antonio PlanchartQ41031224
P2093author name stringSean M Bugel
P2860cites workReduce, Refine, ReplaceQ85224911
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafishQ85888901
Acute toxicity of acetylsalicylic acid to juvenile and embryonic stages of Danio rerioQ85962984
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathyQ24313460
Dominant-negative ALK2 allele associates with congenital heart defectsQ24337521
Efficient genome editing in zebrafish using a CRISPR-Cas systemQ24610828
Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio).Q24813093
Zebrafish sex determination and differentiation: involvement of FTZ-F1 genesQ24814402
Zebrafish model systems for developmental neurobehavioral toxicologyQ27025640
How to improve R&D productivity: the pharmaceutical industry's grand challengeQ28314992
Zebrafish: an in vivo model for nano EHS studiesQ28388653
Perturbation of defense pathways by low-dose arsenic exposure in zebrafish embryosQ28389519
Chemical screening for hair cell loss and protection in the zebrafish lateral lineQ28468560
Fluorescent transgenic zebrafish Tg(nkx2.2a:mEGFP) provides a highly sensitive monitoring tool for neurotoxinsQ28485923
Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicityQ28488006
Sox9 is required for cartilage formationQ28588649
A male-specific role for SOX9 in vertebrate sex determinationQ28594894
The zebrafish reference genome sequence and its relationship to the human genomeQ29616593
Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposureQ29617316
Toward a new U.S. chemicals policy: rebuilding the foundation to advance new science, green chemistry, and environmental healthQ30397312
Persistent adverse effects on health and reproduction caused by exposure of zebrafish to 2,3,7,8-tetrachlorodibenzo-p-dioxin during early development and gonad differentiationQ30481777
Using the zebrafish lateral line to screen for ototoxicityQ30489369
Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowthQ30538184
Development of nanoparticle libraries for biosensingQ33231789
2,3,7,8-Tetrachlorodibenzo-p-dioxin upregulates FoxQ1b in zebrafish jaw primordium.Q33729675
Identification and developmental expression of the full complement of Cytochrome P450 genes in ZebrafishQ33750732
Automated feature detection and imaging for high-resolution screening of zebrafish embryosQ33891430
Efficient recovery of ENU-induced mutations from the zebrafish germlineQ33962803
A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signalingQ34024352
Zebrafish developmental screening of the ToxCast™ Phase I chemical library.Q34105781
AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafishQ34126609
Disposition of ethanol in human maternal venous blood and amniotic fluidQ34271582
Duplication and divergence: the evolution of new genes and old ideasQ34371877
Amniotic fluid: not just fetal urine anymoreQ34414762
Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptorQ42713083
Ethanol exposure induces upregulation of specific microRNAs in zebrafish embryosQ42721705
tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regenerationQ42766102
Targeted gene disruption in somatic zebrafish cells using engineered TALENsQ42862072
Detection of phytoestrogens in samples of second trimester human amniotic fluid.Q43913293
Molecular characterization of three estrogen receptor forms in zebrafish: binding characteristics, transactivation properties, and tissue distributionsQ44000536
REACH: next step to a sound chemicals managementQ44161741
Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafishQ44414140
Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafishQ44527177
High-content screening assay for identification of chemicals impacting cardiovascular function in zebrafish embryosQ44821853
A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin developmentQ45249861
Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock.Q45931271
Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model.Q45963212
Acute neuroactive drug exposures alter locomotor activity in larval zebrafish.Q45998921
Determinants of organochlorine levels detectable in the amniotic fluid of women from Tenerife Island (Canary Islands, Spain).Q46031882
A category approach to predicting the developmental (neuro) toxicity of organotin compounds: the value of the zebrafish (Danio rerio) embryotoxicity test (ZET).Q46043331
Cardiovascular risk assessment of atypical antipsychotic drugs in a zebrafish modelQ46591770
Xenobiotic phenols in early pregnancy amniotic fluidQ46660729
Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heartQ46784297
Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus heartsQ46802509
Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis.Q47073323
Blocking expression of AHR2 and ARNT1 in zebrafish larvae protects against cardiac toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxinQ47074003
Insertional mutagenesis and rapid cloning of essential genes in zebrafishQ48058704
Assessments of the effects of nicotine and ketamine using tyrosine hydroxylase-green fluorescent protein transgenic zebrafish as biosensors.Q48110922
Histological and stereological evaluation of zebrafish (Danio rerio) spermatogenesis with an emphasis on spermatogonial generations.Q48672929
Androgen receptor gene expression in the developing and adult zebrafish brainQ48909471
Cyp1a reporter zebrafish reveals target tissues for dioxin.Q50481783
Zebrafish cardiac enhancer trap lines: new tools for in vivo studies of cardiovascular development and disease.Q50569796
Fishing for teratogens: a consortium effort for a harmonized zebrafish developmental toxicology assay.Q50690821
Chronic nanoparticulate silver exposure results in tissue accumulation and transcriptomic changes in zebrafish.Q50759262
Inhibition of vitellogenin gene induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio).Q50776181
Comparison of molecular and histological changes in zebrafish gills exposed to metallic nanoparticles.Q51669379
Feasibility study of the zebrafish assay as an alternative method to screen for developmental toxicity and embryotoxicity using a training set of 27 compounds.Q51856293
Effect-directed analysis of municipal landfill soil reveals novel developmental toxicants in the zebrafish Danio rerio.Q51858347
Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos.Q51934760
Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes.Q52009655
Heritable gene targeting in zebrafish using customized TALENs.Q55054727
Toxicity assessment of TiO2 nanoparticles in zebrafish embryos under different exposure conditionsQ60664491
[Optical and electron microscopy studies of human fetal membranes. 2. Chorion and decidua]Q70556887
Maternal ingestion of ortho-aminoacetophenone during gestation affects intake by offspringQ70941944
[On the prognosis and therapy of severe abnormalities of the extremities]Q79442479
Non destructive in vivo measurement of ethoxyresorufin biotransformation by zebrafish prolarva: development and applicationQ79906385
Effects of nano-scale TiO2, ZnO and their bulk counterparts on zebrafish: acute toxicity, oxidative stress and oxidative damageQ83375700
Thyroid hormones in growth and development of fish.Q34460203
Inhibition of follicular development, vitellogenesis, and serum 17beta-estradiol concentrations in zebrafish following chronic, sublethal dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxinQ34480956
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.Q34618217
Cadmium sulfate and CdTe-quantum dots alter DNA repair in zebrafish (Danio rerio) liver cellsQ34774349
New school in liver development: lessons from zebrafishQ34998404
Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition.Q35038153
High-content screening assay for identification of chemicals impacting spontaneous activity in zebrafish embryosQ35064824
Systematic evaluation of nanomaterial toxicity: utility of standardized materials and rapid assaysQ35073114
Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryosQ35138548
Craniofacial abnormalities and altered wnt and mmp mRNA expression in zebrafish embryos exposed to gasoline oxygenates ETBE and TAME.Q35234130
Genetic architecture of susceptibility to PCB126-induced developmental cardiotoxicity in zebrafishQ35466328
Concentrations and speciation of polybrominated diphenyl ethers in human amniotic fluid.Q35783399
Automated zebrafish chorion removal and single embryo placement: optimizing throughput of zebrafish developmental toxicity screensQ35891136
Small zebrafish in a big chemical pond.Q35951647
In vivo drug discovery in the zebrafishQ36028226
In vivo cell biology: following the zebrafish trendQ36365794
Polychlorinated biphenyls (PCBs): routes of exposure and effects on human healthQ36478582
Dioxin inhibits zebrafish epicardium and proepicardium developmentQ36551441
In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regenerationQ36580281
TCDD inhibits heart regeneration in adult zebrafishQ36620472
Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish modelQ36718274
Gold nanoparticles disrupt zebrafish eye development and pigmentationQ36873778
Determination of bisphenol-A levels in human amniotic fluid samples by liquid chromatography coupled with mass spectrometry.Q36996426
A systematic genome-wide analysis of zebrafish protein-coding gene functionQ37094235
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Q37121662
Impaired cardiovascular function caused by different stressors elicits a common pathological and transcriptional response in zebrafish embryosQ37139540
Zebrafish: a predictive model for assessing drug-induced toxicityQ37158698
Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cellsQ37166985
Morpholino-mediated knockdown of ERα, ERβa, and ERβb mRNAs in zebrafish (Danio rerio) embryos reveals differential regulation of estrogen-inducible genesQ37240198
AHR-dependent misregulation of Wnt signaling disrupts tissue regenerationQ37304494
Multidimensional in vivo hazard assessment using zebrafishQ37412007
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasisQ37416219
Sox9b is required for epicardium formation and plays a role in TCDD-induced heart malformation in zebrafishQ37422758
A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening.Q37438503
Zebrafish as a correlative and predictive model for assessing biomaterial nanotoxicityQ37457191
Endocrine/paracrine control of zebrafish ovarian developmentQ37465490
A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicityQ37537655
Perspectives on fish gonadotropins and their receptors.Q37581152
Using zebrafish as a model system for studying the transgenerational effects of dioxinQ37683649
Zebrafish as a model to study cardiac development and human cardiac diseaseQ37878169
Zebrafish: as an integrative model for twenty-first century toxicity testing.Q37935725
Light sheet microscopy for real-time developmental biologyQ37941362
Systematic approaches to toxicology in the zebrafishQ37948151
Uncovering the molecular and cellular mechanisms of heart development using the zebrafish.Q38043058
Cancer genetics and the cardiotoxicity of the therapeutics.Q38074793
Zebrafish as a genetic model in pre-clinical drug testing and screeningQ38092194
Mitophagy and neurodegeneration: the zebrafish model systemQ38128482
Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.Q38314794
Germ-line transmission of a myocardium-specific GFP transgene reveals critical regulatory elements in the cardiac myosin light chain 2 promoter of zebrafishQ38350936
In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryosQ38408299
Toxicity assessment of zebrafish following exposure to CdTe QDs.Q38425201
Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafishQ39135063
Acute cardiovascular toxicity of sterilizers, PHMG, and PGH: severe inflammation in human cells and heart failure in zebrafishQ39229661
Alginate based 3D hydrogels as an in vitro co-culture model platform for the toxicity screening of new chemical entities.Q39490904
Why the toxic substances control act needs an overhaul, and how to strengthen oversight of chemicals in the interimQ39752316
Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish developmentQ40001260
Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore waterQ41171822
The effects of carbaryl on the development of zebrafish (Danio rerio) embryosQ41774893
Studies on sensitivity of zebrafish as a model organism for Parkinson's disease: Comparison with rat modelQ41929128
In vivo quantitative study of sized-dependent transport and toxicity of single silver nanoparticles using zebrafish embryosQ41936069
Exxon Valdez to Deepwater Horizon: comparable toxicity of both crude oils to fish early life stagesQ41967038
A rapid throughput approach identifies cognitive deficits in adult zebrafish from developmental exposure to polybrominated flame retardants.Q41979033
Maternal smoking and elevation of catecholamines and metabolites in the amniotic fluidQ42270525
20 years of toxicologyQ42434942
Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicalsQ42710932
P433issue4
P921main subjectDanio rerioQ169444
ichthyotoxicityQ113562277
P304page(s)341-352
P577publication date2014-09-01
P1433published inCurrent Environmental Health ReportsQ23930045
P1476titleZebrafish: A marvel of high-throughput biology for 21(st) century toxicology
P478volume1

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cites work (P2860)
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Q42694450Comparative Developmental Toxicity of Flavonoids Using an Integrative Zebrafish System
Q42374032Comparative study of herbal plants on the phenolic and flavonoid content, antioxidant activities and toxicity on cells and zebrafish embryo.
Q39030456Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models
Q60300757Folic acid-nanoscale gadolinium-porphyrin metal-organic frameworks: fluorescence and magnetic resonance dual-modality imaging and photodynamic therapy in hepatocellular carcinoma
Q38726285High throughput in vitro and in vivo screening of inland waters of Southern California
Q39652047High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance of Intact Zebrafish Embryos Detects Metabolic Changes Following Exposure to Teratogenic Polymethoxyalkenes from Algae
Q35930494In Vivo Screening Using Transgenic Zebrafish Embryos Reveals New Effects of HDAC Inhibitors Trichostatin A and Valproic Acid on Organogenesis
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Q33632087Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs
Q37495218MicroRNA-based screens for synthetic lethal interactions with c-Myc
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Q39564698Optimizing multi-dimensional high throughput screening using zebrafish.
Q37548456PFOS, PFNA, and PFOA sub-lethal exposure to embryonic zebrafish have different toxicity profiles in terms of morphometrics, behavior and gene expression
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Q60049521Silica-gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity
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Q93180069Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish

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