scholarly article | Q13442814 |
P2093 | author name string | Jun Qin | |
Chuanyue Wu | |||
P2860 | cites work | Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily | Q24290812 |
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading | Q24291182 | ||
Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility | Q24295189 | ||
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression | Q24296236 | ||
Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase | Q24312707 | ||
EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility | Q24312896 | ||
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase | Q24314398 | ||
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation | Q24314737 | ||
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites | Q24318346 | ||
The protein kinase complement of the human genome | Q24324497 | ||
The structural basis of integrin-linked kinase-PINCH interactions | Q24324678 | ||
Integrin-linked kinase--essential roles in physiology and cancer biology. | Q37272385 | ||
Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails | Q37360853 | ||
Pseudokinases-remnants of evolution or key allosteric regulators? | Q37809200 | ||
How integrins control mammary epithelial differentiation: a possible role for the ILK-PINCH-Parvin complex | Q37875475 | ||
Integrin-linked kinase: not so 'pseudo' after all. | Q37878251 | ||
A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells | Q39656305 | ||
Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure | Q41866389 | ||
Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae | Q42066604 | ||
Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation | Q42164315 | ||
C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo | Q42442207 | ||
C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes | Q43996515 | ||
Analysis of PINCH function inDrosophilademonstrates its requirement in integrin-dependent cellular processes | Q44433257 | ||
Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension | Q44970101 | ||
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. | Q45986472 | ||
UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle | Q47068850 | ||
Functional analysis of parvin and different modes of IPP-complex assembly at integrin sites during Drosophila development. | Q47072405 | ||
Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor. | Q54527822 | ||
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells | Q24554520 | ||
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization | Q24655829 | ||
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction | Q24679147 | ||
The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions | Q27646573 | ||
The Structure of -Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly | Q27650706 | ||
Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin | Q27652592 | ||
PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival | Q28208706 | ||
Integrin-linked kinase is an adaptor with essential functions during mouse development | Q28261429 | ||
Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase | Q28297327 | ||
Integrin signalling adaptors: not only figurants in the cancer story | Q28299126 | ||
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation | Q28585627 | ||
Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality | Q28586464 | ||
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage | Q28586746 | ||
PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes | Q28586847 | ||
Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling | Q28588987 | ||
Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation | Q28749480 | ||
The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! | Q33668166 | ||
Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy | Q33916456 | ||
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha | Q33968025 | ||
Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase. | Q34039002 | ||
Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival | Q34337340 | ||
Emerging roles of pseudokinases | Q34552850 | ||
A central multifunctional role of integrin-linked kinase at muscle attachment sites. | Q34727923 | ||
Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase. | Q35065294 | ||
The PINCH-ILK-parvin complexes: assembly, functions and regulation. | Q35832718 | ||
Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes | Q35941444 | ||
LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration. | Q35987858 | ||
The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1. | Q36082636 | ||
Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle | Q36095693 | ||
PINCH, N(i)ck and the ILK: network wiring at cell-matrix adhesions | Q36220227 | ||
CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt | Q36323145 | ||
Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane | Q36379951 | ||
Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly | Q37002952 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 607-13 | |
P577 | publication date | 2012-10-01 | |
P1433 | published in | Current Opinion in Cell Biology | Q13505682 |
P1476 | title | ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling | |
P478 | volume | 24 |
Q90440019 | A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation |
Q37622579 | A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease |
Q38122230 | A pickup in pseudokinase activity |
Q41510993 | Activated Integrin-Linked Kinase Negatively Regulates Muscle Cell Enhancement Factor 2C in C2C12 Cells |
Q38075788 | Cell-matrix adhesion of podocytes in physiology and disease |
Q36373441 | Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis |
Q27680416 | Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus |
Q92619249 | Coordinated Expression of Ras Suppressor 1 (RSU-1) and Growth Differentiation Factor 15 (GDF15) Affects Glioma Cell Invasion |
Q34264538 | Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation |
Q36041722 | Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury |
Q93118372 | Emerging regulators of vascular smooth muscle cell migration |
Q38805359 | Endothelial cell-derived matrix promotes the metabolic functional maturation of hepatocyte via integrin-Src signalling. |
Q36257598 | Evidence for Integrin - Venus Kinase Receptor 1 Alliance in the Ovary of Schistosoma mansoni Females Controlling Cell Survival. |
Q38754752 | Exploring the diversity of protein modifications: special bacterial phosphorylation systems |
Q49808354 | Expression of Wnt and integrin pathways in colorectal laterally spreading tumors and their correlation with endoscopic subtypes |
Q27005889 | Extracellular and Intracellular Signaling for Neuronal Polarity |
Q91986620 | ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling |
Q33689045 | Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach |
Q61133333 | Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin |
Q60920838 | Inhibition of Breast Cancer Cell Invasion by Ras Suppressor-1 (RSU-1) Silencing Is Reversed by Growth Differentiation Factor-15 (GDF-15) |
Q92480194 | Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance |
Q47140528 | Integrin and FAK Regulation of Human Pluripotent Stem Cells. |
Q26823123 | Integrin cytoplasmic tail interactions |
Q51087956 | Integrin linked kinase regulates syncytialization of BeWo trophoblast cells. |
Q90124520 | Integrin α9 depletion promotes β-catenin degradation to suppress triple-negative breast cancer tumor growth and metastasis |
Q38748841 | Integrin-Linked Kinase Regulates Bone Formation by Controlling Cytoskeletal Organization and Modulating BMP and Wnt Signaling in Osteoprogenitors. |
Q50993502 | Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease. |
Q44121201 | Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF). |
Q97524384 | Integrin-linked kinase improves uterine receptivity formation by activating Wnt/β-catenin signaling and up-regulating MMP-3/9 expression |
Q50232950 | Integrin-linked kinase inhibition attenuates permeability of the streptozotocin-induced diabetic rat retina |
Q33762944 | Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. |
Q44963993 | Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation. |
Q39096530 | Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer |
Q42829073 | Integrins as Modulators of Transforming Growth Factor Beta Signaling in Dermal Fibroblasts During Skin Regeneration After Injury |
Q36715966 | Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia. |
Q36553567 | Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases |
Q27640530 | Molecular Basis of Kindlin-2 Binding to Integrin-linked Kinase Pseudokinase for Regulating Cell Adhesion |
Q38869424 | Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology. |
Q37021563 | Molecular interactions of ErbB1 (EGFR) and integrin-β1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance |
Q58115566 | Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion |
Q39226865 | Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases |
Q34619203 | Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways. |
Q37176638 | Overexpression of FXYD-3 is involved in the tumorigenesis and development of esophageal squamous cell carcinoma |
Q91698199 | PINCH-1 interacts with myoferlin to promote breast cancer progression and metastasis |
Q90031702 | Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt |
Q38940494 | Podocyte-actin dynamics in health and disease |
Q61806740 | Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage |
Q36124192 | Rsu1 contributes to cell adhesion and spreading in MCF10A cells via effects on P38 map kinase signaling |
Q37468130 | Rsu1 contributes to regulation of cell adhesion and spreading by PINCH1-dependent and - independent mechanisms |
Q38945219 | Signaling via PINCH: Functions, binding partners and implications in human diseases |
Q43529005 | Small interfering RNA targeting ILK inhibits metastasis in human tongue cancer cells through repression of epithelial-to-mesenchymal transition |
Q37725588 | Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells. |
Q24310471 | The EHEC-host interactome reveals novel targets for the translocated intimin receptor |
Q35561072 | The coordinate cellular response to insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-2 (IGFBP-2) is regulated through vimentin binding to receptor tyrosine phosphatase β (RPTPβ) |
Q27026837 | The functional sites of miRNAs and lncRNAs in gastric carcinogenesis |
Q38263509 | The importance of podocyte adhesion for a healthy glomerulus |
Q35078592 | The integrin-linked kinase-PINCH-parvin complex supports integrin αIIbβ3 activation |
Q26825105 | The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration |
Q38181120 | The role of integrins in the development and homeostasis of the epidermis and skin appendages |
Q37636949 | The tumor suppressor gene ARHI (DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms |
Q93275066 | Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish |
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