scholarly article | Q13442814 |
P2093 | author name string | Jun Qin | |
Chuanyue Wu | |||
Sudhiranjan Gupta | |||
Ka Chen | |||
Koichi Fukuda | |||
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The protein kinase complement of the human genome | Q24324497 | ||
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A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction | Q24679147 | ||
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The Structure of -Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly | Q27650706 | ||
Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase | Q27651185 | ||
Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin | Q27652592 | ||
Structure of the Pseudokinase VRK3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site | Q27653415 | ||
ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity | Q27653416 | ||
Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors | Q27653491 | ||
ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor | Q27655851 | ||
The atomic structure of protein-protein recognition sites | Q27861113 | ||
Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343 | Q28213632 | ||
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair | Q28295270 | ||
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation | Q28585627 | ||
Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation | Q28610904 | ||
Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA | Q28910196 | ||
Regulation of protein kinases; controlling activity through activation segment conformation | Q29620471 | ||
Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase | Q30661698 | ||
Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. | Q33762935 | ||
Emerging roles of pseudokinases | Q34552850 | ||
The PINCH-ILK-parvin complexes: assembly, functions and regulation. | Q35832718 | ||
Integrin-linked kinase: a cancer therapeutic target unique among its ILK. | Q35998768 | ||
Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane | Q36379951 | ||
ILK, PINCH and parvin: the tIPP of integrin signalling | Q36403372 | ||
A helix scaffold for the assembly of active protein kinases | Q36871421 | ||
Spatial coordination of actin polymerization and ILK-Akt2 activity during endothelial cell migration | Q37216047 | ||
Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus | Q41869916 | ||
cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer | Q42844060 | ||
C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes | Q43996515 | ||
Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1. | Q44101117 | ||
Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension | Q44970101 | ||
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Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. | Q45986472 | ||
Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor | Q46127942 | ||
Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival. | Q52564100 | ||
Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling. | Q52572083 | ||
Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR | Q57236274 | ||
A modular polycistronic expression system for overexpressing protein complexes in Escherichia coli | Q73404849 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 819-30 | |
P577 | publication date | 2009-12-11 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions | |
P478 | volume | 36 |
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Q34376382 | A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties |
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Q35065294 | Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase. |
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Q50878637 | Characterization of Ligand Binding to Pseudokinases Using a Thermal Shift Assay. |
Q38122228 | Dawn of the dead: protein pseudokinases signal new adventures in cell biology |
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Q37874363 | Extracellular matrix receptors in branched organs |
Q37452962 | Focal adhesion complex proteins in epidermis and squamous cell carcinoma. |
Q38307398 | Going for broke: targeting the human cancer pseudokinome |
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Q38122232 | ILK: a pseudokinase with a unique function in the integrin-actin linkage |
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Q50993502 | Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease. |
Q37220527 | Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer. |
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Q28749480 | Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation |
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Q35180008 | Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi |
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Q24310715 | Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling |
Q91734519 | Kindlin-2 interacts with a highly conserved surface of ILK to regulate focal adhesion localization and cell spreading |
Q30588724 | LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase |
Q35987858 | LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration. |
Q27640530 | Molecular Basis of Kindlin-2 Binding to Integrin-linked Kinase Pseudokinase for Regulating Cell Adhesion |
Q28508913 | Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice |
Q27670909 | NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold |
Q58115566 | Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion |
Q39226865 | Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases |
Q38641286 | Nucleotide-binding mechanisms in pseudokinases |
Q38974336 | Opportunities to Target Specific Contractile Abnormalities with Smooth Muscle Protein Kinase Inhibitors |
Q35147563 | PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma |
Q42021259 | Parvin-ILK: An intimate relationship |
Q35035005 | Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence |
Q92237404 | Prospects for pharmacological targeting of pseudokinases |
Q36060746 | Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog |
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Q38122245 | Pseudokinase drug intervention: a potentially poisoned chalice. |
Q37809200 | Pseudokinases-remnants of evolution or key allosteric regulators? |
Q30397636 | Pseudokinases: update on their functions and evaluation as new drug targets |
Q28485871 | Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex |
Q61806740 | Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage |
Q54356684 | Role of integrin signalling through integrin-linked kinase in skin physiology and pathology. |
Q36124192 | Rsu1 contributes to cell adhesion and spreading in MCF10A cells via effects on P38 map kinase signaling |
Q37468130 | Rsu1 contributes to regulation of cell adhesion and spreading by PINCH1-dependent and - independent mechanisms |
Q39126951 | Scaffolding Function of PI3Kgamma Emerges from Enzyme's Shadow |
Q33916456 | Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy |
Q28512119 | Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response |
Q24295139 | Structural basis for paxillin binding and focal adhesion targeting of β-parvin |
Q33627422 | Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding |
Q42611868 | Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association |
Q30360903 | Suppressor mutations suggest a surface on PAT-4 (Integrin-linked Kinase) that interacts with UNC-112 (Kindlin). |
Q38122229 | Techniques to examine nucleotide binding by pseudokinases |
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Q34283543 | The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases |
Q47297232 | The binding interface of kindlin-2 and ILK involves Asp344/Asp352/Thr356 in kindlin-2 and Arg243/Arg334 in ILK. |
Q39038865 | The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation |
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