Role of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes.

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Role of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes. is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00726-016-2270-8
P698PubMed publication ID27270573

P50authorThung-S LaiQ87605521
P2093author name stringCharles S Greenberg
Cheng-Jui Lin
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Identification of two GTP-independent alternatively spliced forms of tissue transglutaminase in human leukocytes, vascular smooth muscle, and endothelial cellsQ33289840
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Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomesQ33893946
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Tissue transglutaminase constitutively activates HIF-1α promoter and nuclear factor-κB via a non-canonical pathwayQ34489967
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Characterization of heparin-binding site of tissue transglutaminase: its importance in cell surface targeting, matrix deposition, and cell signalingQ35921509
The dynamic dialogue between cells and matrices: implications of fibronectin's elasticityQ35964046
Histamine receptors of the microvascular endothelium revealed in situ with a histamine-ferritin conjugate: characteristic high-affinity binding sites in venulesQ36208951
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γ-Glutamylamines and neurodegenerative diseasesQ36377238
Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nucleiQ36395820
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Identification of a novel recognition sequence for fibronectin within the NH2-terminal beta-sandwich domain of tissue transglutaminaseQ38327580
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Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E.Q39387300
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Cell-based assay for monitoring transglutaminase activityQ40510673
Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.Q40526299
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Lysine-rich histone (H1) is a lysyl substrate of tissue transglutaminase: possible involvement of transglutaminase in the formation of nuclear aggregates in (CAG)(n)/Q(n) expansion diseasesQ40735275
Interaction of tissue transglutaminase with nuclear transport protein importin-alpha3.Q40963729
Transglutaminase induced by epidermal growth factor negatively regulates the growth signal in primary cultured hepatocytesQ41766549
Residues in the synuclein consensus motif of the α-synuclein fragment, NAC, participate in transglutaminase-catalysed cross-linking to Alzheimer-disease amyloid βA4 peptideQ41830649
Exposure of βL-crystallin to oxidizing free radicals enhances its susceptibility to transglutaminase activityQ41884195
Beta-actin is a target for transglutaminase activity at synaptic endings in chicken telencephalic cell culturesQ42016431
Transglutaminase catalyses the modification of glutamine side chains in the C-terminal region of bovine beta-lactoglobulinQ42111128
Déjà vu with a twist: transglutaminases in bioenergetics and transcriptional dysfunction in Huntington's diseaseQ42204907
Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.Q42826591
Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminaseQ43577448
N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's diseaseQ43820046
Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surfaceQ43863360
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamineQ43873037
'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's diseaseQ44104440
Thrombospondin and fibrinogen bind serotonin-derivatized proteins on COAT-plateletsQ44155386
Tissue transglutaminase mediates activation of RhoA and MAP kinase pathways during retinoic acid-induced neuronal differentiation of SH-SY5Y cellsQ44195410
Differential incorporation of biotinylated polyamines by transglutaminase 2.Q44277951
Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminaseQ44387021
Histaminylation of fibrinogen by tissue transglutaminase-2 (TGM-2): potential role in modulating inflammationQ44389678
Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.Q44792358
Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease.Q45232035
Covalent blocking of fibril formation and aggregation of intracellular amyloidgenic proteins by transglutaminase-catalyzed intramolecular cross-linkingQ45255077
Paradoxical inhibition of protein aggregation and precipitation by transglutaminase-catalyzed intermolecular cross-linkingQ45282574
P433issue3
P304page(s)501-515
P577publication date2016-06-06
P1433published inAmino AcidsQ15757015
P1476titleRole of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes
P478volume49