The headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activation

scientific journal article

The headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.00237-08
P932PMC publication ID2493358
P698PubMed publication ID18505823
P5875ResearchGate publication ID5344757

P50authorAthar H ChishtiQ89175184
P2093author name stringMorvarid Mohseni
P2860cites workLoss of heterozygosity on 8p in prostate cancer implicates a role for dematin in tumor progressionQ22010806
Cloning of human erythroid dematin reveals another member of the villin familyQ24310645
Isoform cloning, actin binding, and chromosomal localization of human erythroid dematin, a member of the villin superfamilyQ24318833
Headpiece domain of dematin is required for the stability of the erythrocyte membraneQ24531210
Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathwayQ24671083
Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domainsQ24672461
Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G proteinQ28248311
Identification of a mouse p21Cdc42/Rac activated kinaseQ28289355
Interaction of focal adhesion kinase with cytoskeletal protein talinQ28294149
Cooperation between mDia1 and ROCK in Rho-induced actin reorganizationQ28587275
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesisQ29547538
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonQ29620156
Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domainQ30194432
Dematin interacts with the Ras-guanine nucleotide exchange factor Ras-GRF2 and modulates mitogen-activated protein kinase pathwaysQ34115142
Rho GTPases and the control of cell behaviourQ34462373
Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeabilityQ34470253
Partial purification and characterization of an actin-bundling protein, band 4.9, from human erythrocytesQ36211843
Activation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domainsQ36255267
Novel signaling pathways mediating reciprocal control of keratinocyte migration and wound epithelialization through M3 and M4 muscarinic receptorsQ36322315
Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in plateletsQ36532167
Villin: The major microfilament-associated protein of the intestinal microvillusQ37330654
MIP-1alpha as a critical macrophage chemoattractant in murine wound repairQ37380909
ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cellsQ38314143
The spectrin-actin junction of erythrocyte membrane skeletonsQ38596118
The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-delta to focal adhesions.Q42797509
Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP-kinase and focal adhesion kinase in cultured Swiss 3T3 cellsQ42807086
cDNA sequence, genomic structure, and expression of the mouse dematin gene (Epb4.9).Q47925262
Purification of erythrocyte dematin (protein 4.9) reveals an endogenous protein kinase that modulates actin-bundling activity.Q52246312
Abolition of actin-bundling by phosphorylation of human erythrocyte protein 4.9.Q52250577
Combined deletion of mouse dematin-headpiece and beta-adducin exerts a novel effect on the spectrin-actin junctions leading to erythrocyte fragility and hemolytic anemiaQ79401138
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectwound healingQ1509074
Dematin actin binding proteinQ21497475
P304page(s)4712–4718
P577publication date2008-08-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activation
P478volume28

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cites work (P2860)
Q39661349A specific isoform of glial cell line‐derived neurotrophic factor family receptor alpha 1 regulates RhoA expression and glioma cell migration
Q37076428Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia
Q24300718Headpiece domain of dematin regulates calcium mobilization and signaling in platelets
Q59793928Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation
Q35891195Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis
Q42134416Regulatory models of RhoA suppression by dematin, a cytoskeletal adaptor protein
Q24312481The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9)
Q37122360Transcriptional mechanisms underlying hemoglobin synthesis

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