Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

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Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M408130200
P698PubMed publication ID15569683

P50authorShigetsugu HatakeyamaQ39908557
P2093author name stringKeiichi I Nakayama
Hisato Saitoh
Hidehisa Takahashi
P2860cites workIdentification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1Q22009137
A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteinsQ22010974
Regulation and localization of the Bloom syndrome protein in response to DNA damageQ24291133
Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modificationQ24291154
U box proteins as a new family of ubiquitin-protein ligasesQ24291397
PML colocalizes with and stabilizes the DNA damage response protein TopBP1Q24303540
Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.Q38330113
SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activitiesQ42816242
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Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperonesQ44930825
Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylaseQ47724741
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p300 Transcriptional Repression Is Mediated by SUMO ModificationQ60304936
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2Q24317523
Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylaseQ24320042
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-cateninQ24534109
Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnoverQ24534803
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylaseQ24534918
SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damageQ24682811
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1Q24685095
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.Q27937465
The nucleoporin RanBP2 has SUMO1 E3 ligase activityQ28115025
The polycomb protein Pc2 is a SUMO E3Q28115324
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.Q28117154
The transcriptional role of PML and the nuclear bodyQ28144176
Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motifQ28144708
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3Q28145507
An E3-like factor that promotes SUMO conjugation to the yeast septinsQ28188846
Involvement of PIAS1 in the sumoylation of tumor suppressor p53Q28189956
PML protein isoforms and the RBCC/TRIM motifQ28204823
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activationQ28282094
Identification of three major sentrinization sites in PMLQ28284098
Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1Q28512334
The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiersQ28616490
Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding ProteinsQ29619145
Nuclear and unclear functions of SUMOQ29903594
Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting proteinQ33615409
SUMO, ubiquitin's mysterious cousinQ33939449
A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systemsQ33951379
SUMO: of branched proteins and nuclear bodiesQ34435551
Role and fate of PML nuclear bodies in response to interferon and viral infectionsQ34435571
Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2.Q34452072
A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligasesQ34455419
A superfamily of protein tags: ubiquitin, SUMO and related modifiersQ35162583
RanBP2 associates with Ubc9p and a modified form of RanGAP1Q36105014
Preferential interaction of sentrin with a ubiquitin-conjugating enzyme, Ubc9.Q36888922
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
thymineQ171973
Thymine DNA glycosylaseQ21989641
P304page(s)5611-5621
P577publication date2004-11-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleNoncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein
P478volume280

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