| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.BPG.2010.07.007 |
| P953 | full work available at URL | https://api.elsevier.com/content/article/PII:S1521691810000867?httpAccept=text/plain |
| https://api.elsevier.com/content/article/PII:S1521691810000867?httpAccept=text/xml | ||
| P3181 | OpenCitations bibliographic resource ID | 2709737 |
| P698 | PubMed publication ID | 20955959 |
| P2093 | author name string | Christian P. Strassburg | |
| P2860 | cites work | Alteration of drug metabolism in Gilbert's syndrome | Q24541387 |
| UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer | Q24648015 | ||
| Genome-wide association meta-analysis for total serum bilirubin levels | Q24658179 | ||
| UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients | Q24806179 | ||
| Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial | Q28036747 | ||
| Human UDP-glucuronosyltransferases: metabolism, expression, and disease | Q28145608 | ||
| Irinotecan treatment in cancer patients with UGT1A1 polymorphisms | Q28178430 | ||
| Chronic idiopathic jaundice with unidentified pigment in liver cells; a new clinicopathologic entity with a report of 12 cases | Q28210828 | ||
| Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity | Q28218156 | ||
| Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan | Q28249001 | ||
| Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia | Q28292517 | ||
| The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1 | Q28574039 | ||
| The linear effects of alpha-thalassaemia, the UGT1A1 and HMOX1 polymorphisms on cholelithiasis in sickle cell disease | Q33288909 | ||
| Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk | Q33379000 | ||
| Heme oxygenase-carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide? | Q33643464 | ||
| Hepatobiliary transport | Q33870213 | ||
| Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene | Q33922044 | ||
| Mechanism of indinavir-induced hyperbilirubinemia | Q33947992 | ||
| Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer | Q33959136 | ||
| Chronic unconjugated hyperbilirubinemia without overt signs of hemolysis in adolescents and adults | Q34026356 | ||
| The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome | Q34057969 | ||
| Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome | Q34374626 | ||
| In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation | Q34445138 | ||
| New insights into the classification and mechanisms of hereditary, chronic, non-haemolytic hyperbilirubinaemias | Q34474465 | ||
| Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. | Q34568821 | ||
| Gilbert syndrome, UGT1A1*28 allele, and cardiovascular disease risk: possible protective effects and therapeutic applications of bilirubin. | Q34762005 | ||
| Pharmacogenetic study in Hodgkin lymphomas reveals the impact of UGT1A1 polymorphisms on patient prognosis. | Q34820468 | ||
| Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan. | Q34975510 | ||
| Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes | Q35045611 | ||
| Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient | Q35603726 | ||
| Bilirubin: an endogenous product of heme degradation with both cytotoxic and cytoprotective properties | Q35842947 | ||
| The apical conjugate efflux pump ABCC2 (MRP2). | Q36539096 | ||
| Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition | Q36544905 | ||
| Rapid allelic discrimination by TaqMan PCR for the detection of the Gilbert's syndrome marker UGT1A1*28. | Q36944278 | ||
| Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism | Q37105826 | ||
| Genetic variations in UGT1A1 and UGT2B7 and endometrial cancer risk | Q37155153 | ||
| Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice | Q37337621 | ||
| Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study. | Q37364279 | ||
| Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes | Q37378223 | ||
| Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10. | Q39755078 | ||
| Gilbert??s Syndrome and Drug Metabolism | Q39806220 | ||
| Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans | Q40895512 | ||
| Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds | Q41130997 | ||
| Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups | Q42528413 | ||
| Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach | Q42989157 | ||
| Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg? | Q43195722 | ||
| Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization | Q43957689 | ||
| Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). | Q44104279 | ||
| A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2). | Q44185435 | ||
| Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment | Q44554472 | ||
| Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects | Q44743146 | ||
| The functional UGT1A1 promoter polymorphism decreases endometrial cancer risk | Q44761827 | ||
| Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). | Q44772647 | ||
| Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 (UGT1A1) and risk of breast cancer | Q44866168 | ||
| Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease | Q44966651 | ||
| Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients | Q45009159 | ||
| Biliary Excretion of Conjugated Sulfobromophthalein (BSP) in Constitutional Conjugated Hyperbilirubinemias | Q45089299 | ||
| Identification and characterization of a functional TATA box polymorphism of the UDP glucuronosyltransferase 1A7 gene | Q45269995 | ||
| Effects of Japanese herbal medicine, Kampo, on human UGT1A1 activity. | Q45943082 | ||
| UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients. | Q46038296 | ||
| Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. | Q46448062 | ||
| Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia | Q46710172 | ||
| Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions | Q46813333 | ||
| Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue | Q46843909 | ||
| UGT1A1 variation and gallstone formation in sickle cell disease | Q47317656 | ||
| Bilirubin and the risk of common non-hepatic diseases. | Q53620391 | ||
| Rotor-type hyperbilirubinaemia has no defect in the canalicular bilirubin export pump | Q59527350 | ||
| The contribution of intestinal UDP-glucuronosyltransferases in modulating 7-ethyl-10-hydroxy-camptothecin (SN-38)-induced gastrointestinal toxicity in rats | Q64377492 | ||
| Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11 | Q68248525 | ||
| A mutation in bilirubin uridine 5'-diphosphate-glucuronosyltransferase isoform 1 causing Crigler-Najjar syndrome type II | Q70767683 | ||
| Hepatic transport of serum bilirubin, bromsulfophthalein, and indocyanine green in patients with congenital non-hemolytic hyperbilirubinemia and patients with constitutional indocyanine green excretory defect | Q71188987 | ||
| Jaundice, genes and promoters | Q73044045 | ||
| Persistent non-hemolytic hyperbilirubinemia associated with lipochrome-like pigment in liver cells: report of four cases | Q73642778 | ||
| UGT1A1 genotypes and glucuronidation of SN-38, the active metabolite of irinotecan | Q77467827 | ||
| Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus | Q77920429 | ||
| Gilbert's disease and atazanavir: from phenotype to UDP-glucuronosyltransferase haplotype | Q79291107 | ||
| Further evidence that the UGT1A1*28 allele is not associated with coronary heart disease: The ECTIM Study | Q79397270 | ||
| UGT1A1 promoter genotype correlates with SN-38 pharmacokinetics, but not severe toxicity in patients receiving low-dose irinotecan | Q80495875 | ||
| Association between the UGT1A1 TA-repeat polymorphism and bilirubin concentration in patients with intermittent claudication: results from the CAVASIC study | Q80979261 | ||
| Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A) | Q82579267 | ||
| Coinheritance of Gilbert syndrome-associated UGT1A1 mutation increases gallstone risk in cystic fibrosis | Q82931817 | ||
| Irinogenetics: what is the right star? | Q83195709 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | bilirubin metabolic disorder | Q390475 |
| Rotor syndrome | Q1512812 | ||
| P304 | page(s) | 555-71 | |
| P577 | publication date | 2010-10-01 | |
| P1433 | published in | Best Practice and Research: Clinical Gastroenterology | Q15754316 |
| P1476 | title | Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome) | |
| P478 | volume | 24 |
| Q54727983 | A Case of Acquired Gilbert's Syndrome. |
| Q64229351 | A Case of Dubin-Johnson Syndrome in Pregnancy |
| Q43973645 | Assessment of safety in hepatic resection for hepatocellular carcinoma focusing on indirect hyperbilirubinemia |
| Q28071435 | Bilirubin in coronary artery disease: Cytotoxic or protective? |
| Q38957221 | Chronically elevated bilirubin protects from cardiac reperfusion injury in the male Gunn rat. |
| Q28257094 | Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver |
| Q34872275 | Crigler-Najjar syndrome type II in a Chinese boy resulting from three mutations in the bilirubin uridine 5'-diphosphate-glucuronosyltransferase (UGT1A1) gene and a family genetic analysis |
| Q45316497 | Defective UGT1A1 causes hyperbilirubinemia |
| Q45316498 | Defective UGT1A4 causes hyperbilirubinemia |
| Q38254730 | Effect of drug transporter pharmacogenetics on cholestasis |
| Q89455763 | Enhanced recovery after surgery with intrathecal opioid in a patient of Gilbert's syndrome undergoing mitral valve replacement |
| Q36746173 | External validation of the bilirubin-atazanavir nomogram for assessment of atazanavir plasma exposure in HIV-1-infected patients |
| Q35079764 | General anesthesia in a patient with Gilbert's syndrome |
| Q37967241 | Gilbert syndrome |
| Q99711709 | Gilbert syndrome with systemic lupus erythematosus presenting with persistent unconjugated hyperbilirubinemia: A case report |
| Q37997047 | Gilbert syndrome: the UGT1A1*28 promoter polymorphism as a biomarker of multifactorial diseases and drug metabolism |
| Q38888365 | Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites |
| Q26776470 | Inherited disorders of bilirubin clearance |
| Q34460668 | Intracytoplasmic crystalline inclusions in the hepatocytes of an antelope |
| Q37714981 | Multicenter phase II clinical trial of nilotinib for patients with imatinib-resistant or -intolerant chronic myeloid leukemia from the East Japan CML study group evaluation of molecular response and the efficacy and safety of nilotinib |
| Q33732910 | NEW INSIGHTS INTO THE PRESENCE OF BILIRUBIN IN A PLANT SPECIES STRELITZIA NICOLAI (STRELITZIACEAE). |
| Q39298701 | Oncology Drug Dosing in Gilbert Syndrome Associated with UGT1A1: A Summary of the Literature |
| Q41099201 | Outcome and toxicities associated to chemotherapy in children with acute lymphoblastic leukemia and Gilbert syndrome. Usefulness of UGT1A1 mutational screening. |
| Q34053116 | PPARα: A Master Regulator of Bilirubin Homeostasis |
| Q35238390 | Perinatal gene transfer to the liver |
| Q50041762 | Perioperative Anesthetic Management of Patients Having Liver Transplantation for Uncommon Conditions |
| Q34307589 | Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects |
| Q92469593 | Serum bilirubin is negatively associated with white blood cell count |
| Q48275297 | Serum total bilirubin concentrations are inversely associated with total white blood cell counts in an adult population |
| Q44384003 | Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia. |
| Q34333710 | The SLCO (former SLC21) superfamily of transporters |
| Q28388309 | Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle |
| Q42181720 | UGT1A1 gene mutation due to Crigler-Najjar syndrome in Iranian patients: identification of a novel mutation. |
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