Oncology Drug Dosing in Gilbert Syndrome Associated with UGT1A1: A Summary of the Literature

scientific article published on 11 May 2017

Oncology Drug Dosing in Gilbert Syndrome Associated with UGT1A1: A Summary of the Literature is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1002/PHAR.1946
P8608Fatcat IDrelease_lv5zhgxztvfvxi7vzgwoo3jf34
P698PubMed publication ID28494109

P50authorJennifer C Y JuppQ89254976
P2093author name stringRoger Y Tsang
Vincent H Ha
P2860cites workThe UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergenceQ24311466
Function, genetic polymorphism, and transcriptional regulation of human UDP-glucuronosyltransferase (UGT) 1A1Q27004072
Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome)Q28295988
Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer.Q33425469
Molecular genetic basis of Gilbert's syndromeQ33756586
Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphismQ33834417
Hepatotoxicity of chemotherapyQ33942794
Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxicsQ34041139
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndromeQ34057969
Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancerQ34565071
Pharmacogenetic study in Hodgkin lymphomas reveals the impact of UGT1A1 polymorphisms on patient prognosis.Q34820468
Ancestry and pharmacogenetics of antileukemic drug toxicityQ35828717
Therapeutic drug monitoring of cancer chemotherapy.Q37018328
Irinotecan and uridine diphosphate glucuronosyltransferase 1A1 pharmacogenetics: to test or not to test, that is the questionQ37249563
Population pharmacokinetic analysis of axitinib in healthy volunteersQ37635202
Gilbert syndromeQ37967241
Mortality outcomes after busulfan-containing conditioning treatment and haemopoietic cell transplantation in patients with Gilbert's syndrome: a retrospective cohort studyQ39101901
Outcome and toxicities associated to chemotherapy in children with acute lymphoblastic leukemia and Gilbert syndrome. Usefulness of UGT1A1 mutational screening.Q41099201
UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenibQ43293587
Hyperbilirubinemia in pazopanib- or sunitinib-treated patients in COMPARZ is associated with UGT1A1 polymorphisms.Q43963256
Association between severe toxicity of nilotinib and UGT1A1 polymorphisms in Japanese patients with chronic myelogenous leukemia.Q44302313
Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia.Q44384003
Glucuronidation of Etoposide in Human Liver Microsomes Is Specifically Catalyzed by UDP-Glucuronosyltransferase 1A1Q44403623
Gilbert's syndrome and fluorouracil toxicity in colorectal cancer patients: which correlation?Q44791732
Doxorubicin dosage guidelines in a patient with hyperbilirubinemia of Gilbert's syndromeQ45114480
Nilotinib-induced hyperbilirubinemia: is it a negligible adverse event?Q45984197
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectGilbert syndromeQ752216
P304page(s)956-972
P577publication date2017-05-11
P1433published inPharmacotherapyQ7180800
P1476titleOncology Drug Dosing in Gilbert Syndrome Associated with UGT1A1: A Summary of the Literature
P478volume37

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cites work (P2860)
Q64114732Association Study Among Candidate Genetic Polymorphisms and Chemotherapy-Related Severe Toxicity in Testicular Cancer Patients
Q89678032Carbon monoxide breath test assessment of mild hemolysis in Gilbert's syndrome
Q99711709Gilbert syndrome with systemic lupus erythematosus presenting with persistent unconjugated hyperbilirubinemia: A case report
Q58695636UGT1A1 (TA)n promoter genotype: Diagnostic and population pharmacogenetic marker in Serbia

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