scholarly article | Q13442814 |
P50 | author | David K Magnuson | Q59489257 |
Robert M. Brownstone | Q37834211 | ||
P2093 | author name string | Nath A | |
Geiger JD | |||
Knudsen BE | |||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | virus | Q808 |
neurotoxicity | Q3338704 | ||
toxic encephalopathy | Q7830379 | ||
P304 | page(s) | 373-380 | |
P577 | publication date | 1995-03-01 | |
P1433 | published in | Annals of Neurology | Q564414 |
P1476 | title | Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity | |
P478 | volume | 37 |
Q40923652 | A macrophage hippocampal slice co-culture system: application to the study of HIV-induced brain damage |
Q33954292 | A second exon splicing silencer within human immunodeficiency virus type 1 tat exon 2 represses splicing of Tat mRNA and binds protein hnRNP H. |
Q34777672 | AIDS dementia |
Q45748893 | Acute in vivo neurotoxicity of peptides from Maedi Visna virus transactivating protein Tat. |
Q48958311 | Altered outward-rectifying K(+) current reveals microglial activation induced by HIV-1 Tat protein |
Q34632979 | Anti-tat Hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages |
Q55315393 | Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation. |
Q37360984 | Apoptosis induced by HIV-1 infection of the central nervous system |
Q48345028 | Benzodiazepines, glia, and HIV-1 neuropathogenesis |
Q35114694 | Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier. |
Q36844731 | Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. |
Q34377373 | Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway |
Q45403949 | Ceftriaxone protects against the neurotoxicity of human immunodeficiency virus proteins |
Q36068289 | Cell death in HIV dementia |
Q42190715 | Cell membrane penetrating function of the nuclear localization sequence in human cytokine IL-1α. |
Q42127774 | Cell-specific actions of HIV-Tat and morphine on opioid receptor expression in glia. |
Q45434461 | Cerebrospinal fluid from human immunodeficiency virus--infected individuals facilitates neurotoxicity by suppressing intracellular calcium recovery |
Q45747316 | Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia |
Q44020129 | Choroid plexus macrophages proliferate and release toxic factors in response to feline immunodeficiency virus |
Q37175474 | Converging roles for sphingolipids and cell stress in the progression of neuro-AIDS |
Q48496328 | Cyclooxygenase-2 is involved in HIV-1 Tat-induced inflammatory responses in the brain |
Q53730529 | Decreased expression of AMPA receptor messenger RNA and protein in AIDS: A model for HIV-associated neurotoxicity |
Q36296748 | Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity |
Q34017924 | Direct effects of HIV-1 Tat on excitability and survival of primary dorsal root ganglion neurons: possible contribution to HIV-1-associated pain |
Q36993831 | Effect of HIV clade differences on the onset and severity of HIV-associated neurocognitive disorders |
Q28660034 | Effects of opiates and HIV proteins on neurons: the role of ferritin heavy chain and a potential for synergism |
Q36902304 | Effects of the HIV-1 viral protein TAT on central neurotransmission: role of group I metabotropic glutamate receptors |
Q37598636 | Effects of valproic acid coadministration on plasma efavirenz and lopinavir concentrations in human immunodeficiency virus-infected adults. |
Q40112882 | Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein |
Q57040576 | Endothelins in inflammatory neurological diseases |
Q37410928 | Enhanced human immunodeficiency virus Type 1 expression and neuropathogenesis in knockout mice lacking Type I interferon responses |
Q24796371 | Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine |
Q33686905 | Estrogen receptor alpha inhibits the estrogen-mediated suppression of HIV transcription in astrocytes: implications for estrogen neuroprotection in HIV dementia |
Q43717540 | Evaluation of HIV-1 Tat induced neurotoxicity in rat cortical cell culture |
Q24671184 | Evidence that Par-4 participates in the pathogenesis of HIV encephalitis |
Q43051856 | Excitatory effects of human immunodeficiency virus 1 Tat on cultured rat cerebral cortical neurons |
Q24683736 | Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes |
Q43657062 | Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages |
Q24813383 | Gonadal steroids differentially modulate neurotoxicity of HIV and cocaine: testosterone and ICI 182,780 sensitive mechanism |
Q33831637 | Gp120 in the pathogenesis of human immunodeficiency virus-associated pain |
Q34405882 | Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel |
Q27023968 | HIV Associated Neurocognitive Disorders |
Q40325425 | HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity. |
Q36565817 | HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors. |
Q38747519 | HIV-1 Tat Promotes Lysosomal Exocytosis in Astrocytes and Contributes to Astrocyte-mediated Tat Neurotoxicity |
Q54220812 | HIV-1 Tat alters neuronal intrinsic excitability. |
Q32061182 | HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors |
Q43496324 | HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells |
Q36944251 | HIV-1 Tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomes |
Q28210557 | HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity |
Q42097093 | HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-κB, AP-1, C/EBPα and C/EBPγ transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways |
Q28144137 | HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells |
Q48447211 | HIV-1 gp120 proteins and gp160 peptides are toxic to brain endothelial cells and neurons: possible pathway for HIV entry into the brain and HIV-associated dementia |
Q44722671 | HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise |
Q44342231 | HIV-1 tat protein upregulates inflammatory mediators and induces monocyte invasion into the brain |
Q30615171 | HIV-1-associated central nervous system dysfunction |
Q82182169 | HIV-TAT protein upregulates expression of multidrug resistance protein 1 in the blood-brain barrier |
Q36302056 | Human brain derived cell culture models of HIV-1 infection |
Q37572418 | Human immunodeficiency virus tat gene transfer to the murine central nervous system using a replication-defective herpes simplex virus vector stimulates transforming growth factor beta 1 gene expression |
Q44775961 | Human immunodeficiency virus type 1 Tat and methamphetamine affect the release and activation of matrix-degrading proteinases |
Q28212110 | Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures |
Q44459049 | Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site |
Q28182166 | Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells |
Q36148402 | Human immunodeficiency virus type-1 protein Tat induces tumor necrosis factor-alpha-mediated neurotoxicity |
Q37218005 | Human immunodeficiency virus-associated dementia: clinical aspects, biology, and treatment |
Q35856188 | Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic |
Q41499525 | Immunologically induced electrophysiological dysfunction: implications for inflammatory diseases of the CNS and PNS. |
Q33971765 | Implications of gliotransmission for the pharmacotherapy of CNS disorders |
Q34621972 | In vitro and animal models of human immunodeficiency virus infection of the central nervous system |
Q35980114 | Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia |
Q37399037 | Inhibition of GABAergic Neurotransmission by HIV-1 Tat and Opioid Treatment in the Striatum Involves μ-Opioid Receptors. |
Q36915824 | Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors |
Q92359782 | Inhibitory Control Deficits Associated with Upregulation of CB1R in the HIV-1 Tat Transgenic Mouse Model of Hand |
Q36984709 | Interactions of HIV and methamphetamine: cellular and molecular mechanisms of toxicity potentiation |
Q34145508 | Interactions of human immunodeficiency virus-1 proteins with neurons: possible role in the development of human immunodeficiency virus-1-associated dementia |
Q34197724 | Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload. |
Q36003890 | Involvement of quinolinic acid in AIDS dementia complex |
Q36166231 | Ketone bodies protection against HIV-1 Tat-induced neurotoxicity |
Q36482308 | Kynurenic Acid Metabolism in Various Types of Brain Pathology in HIV-1 Infected Patients |
Q33882476 | Mechanisms of HIV-tat-induced phosphorylation of N-methyl-D-aspartate receptor subunit 2A in human primary neurons: implications for neuroAIDS pathogenesis |
Q33566813 | Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells |
Q33799373 | Methamphetamine abuse, HIV infection, and neurotoxicity. |
Q33985461 | Methamphetamine toxicity and its implications during HIV-1 infection. |
Q34309557 | Microglia in HIV-associated neurological diseases |
Q33889326 | Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon |
Q36302067 | Molecular and cellular mechanisms of neuronal cell death in HIV dementia |
Q35879801 | Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells. |
Q36302045 | Mononuclear phagocytes in the pathogenesis of neurodegenerative diseases |
Q36109980 | Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice. |
Q28261344 | Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions |
Q36384046 | Multivariable analysis to determine if HIV-1 Tat dicysteine motif is associated with neurodevelopmental delay in HIV-infected children in Malawi |
Q47329696 | Network Analysis of Hippocampal Neurons by Microelectrode Array in the Presence of HIV-1 Tat and Cocaine |
Q35065220 | Neurologic aspects of HIV infection in infants and children: therapeutic approaches and outcome |
Q42745285 | Neuronal PINCH is regulated by TNF-α and is required for neurite extension. |
Q45757726 | Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein. |
Q45728995 | Neuronal injury in hippocampus with human immunodeficiency virus transactivating protein, Tat. |
Q38101560 | Neuronal toxicity in HIV CNS disease |
Q82029838 | Neuropharmacology of HIV/AIDS |
Q34098776 | Neurotoxicity and dysfunction of dopaminergic systems associated with AIDS dementia |
Q42408293 | Neurotoxicity of HIV-1 Tat protein: involvement of D1 dopamine receptor |
Q42493967 | Neurotoxicity of HIV-1 proteins gp120 and Tat in the rat striatum |
Q28578827 | Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism |
Q35557261 | Novel mechanisms of central nervous system damage in HIV infection. |
Q37547409 | Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication |
Q36335033 | Oxidative Stress Is Associated with Neuroinflammation in Animal Models of HIV-1 Tat Neurotoxicity |
Q37002797 | PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells |
Q40727055 | Pathogenic mechanisms of neuronal damage in the AIDS dementia complex |
Q34098796 | Pharmacological frontiers in the treatment of AIDS dementia |
Q40777702 | Pro-inflammatory and pro-oxidant properties of the HIV protein Tat in a microglial cell line: attenuation by 17 beta-estradiol |
Q33795961 | Progesterone protects normative anxiety-like responding among ovariectomized female mice that conditionally express the HIV-1 regulatory protein, Tat, in the CNS. |
Q48930794 | Protection of human cerebral neurons from neurodegenerative insults by gene delivery of soluble tumor necrosis factor p75 receptor |
Q40852719 | Protocol for Detection of HIV-Tat Protein in Cerebrospinal Fluid by a Sandwich Enzyme-Linked Immunosorbent Assay |
Q43717545 | Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat. |
Q93151527 | Reduced intrinsic excitability of CA1 pyramidal neurons in human immunodeficiency virus (HIV) transgenic rats |
Q48461014 | Reduction in phosphorylated heavy neurofilament in the cerebellum in HIV disease |
Q78106920 | Riluzole: a potential therapy for HIV dementia? |
Q44633319 | Role of Na+/H+ exchangers, excitatory amino acid receptors and voltage-operated Ca2+ channels in human immunodeficiency virus type 1 gp120-mediated increases in intracellular Ca2+ in human neurons and astrocytes |
Q26829535 | Role of Oxidative Stress in HIV-1-Associated Neurocognitive Disorder and Protection by Gene Delivery of Antioxidant Enzymes |
Q37519397 | Role of Tat protein in HIV neuropathogenesis |
Q27025573 | Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders |
Q42443945 | SDF-1alpha is expressed in astrocytes and neurons in the AIDS dementia complex: an in vivo and in vitro study. |
Q44276812 | Selective isolation and purification of tat protein via affinity membrane separation |
Q48939388 | Signaling mechanisms of HIV-1 Tat-induced alterations of claudin-5 expression in brain endothelial cells |
Q34162648 | Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia |
Q28354326 | Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro |
Q35613792 | T-cell and neuronal apoptosis in HIV infection: implications for therapeutic intervention |
Q28141149 | Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats |
Q31014821 | The AIDS dementia complex: clinical and basic neuroscience with implications for novel molecular therapies |
Q43822559 | The basic domain in HIV-1 Tat protein as a target for polysulfonated heparin-mimicking extracellular Tat antagonists |
Q33797102 | The human immunodeficiency virus type 1 Tat protein up-regulates the promoter activity of the beta-chemokine monocyte chemoattractant protein 1 in the human astrocytoma cell line U-87 MG: role of SP-1, AP-1, and NF-kappaB consensus sites |
Q45764762 | The human immunodeficiency virus type-1 (HIV-1) Tat protein and Bcl-2 gene expression |
Q44532509 | The human immunodeficiency virus-1 protein Tat and its discrete fragments evoke selective release of acetylcholine from human and rat cerebrocortical terminals through species-specific mechanisms. |
Q48485626 | The immunophilin ligand GPI1046 protects neurons from the lethal effects of the HIV-1 proteins gp120 and Tat by modulating endoplasmic reticulum calcium load |
Q51971267 | The phospholipid mediator platelet-activating factor mediates striatal synaptic facilitation. |
Q33599759 | The regulation of apoptosis by microbial pathogens. |
Q33643184 | The role of microglia and macrophages in the pathophysiology of the CNS. |
Q48377406 | The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system |
Q35024694 | Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C Tat protein |
Q35366778 | Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder |
Q73372679 | Tumor necrosis factor-a attenuates N-methyl-D-aspartate-mediated neurotoxicity in neonatal rat hippocampus |
Q35197030 | Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia |
Q28580077 | Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands |
Q45422129 | Virus replication and disease progression inversely correlate with SIV tat evolution in morphine-dependent and SIV/SHIV-infected Indian rhesus macaques |
Q37060468 | Viruses and the immune system: their roles in seizure cascade development. |
Q36859290 | XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells |
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