Cancer stem cell niche: the place to be

scientific article

Cancer stem cell niche: the place to be is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1158/0008-5472.CAN-10-3220
P3181OpenCitations bibliographic resource ID755746
P698PubMed publication ID21266356

P50authorJan Paul MedemaQ89296672
P2093author name stringLouis Vermeulen
Tijana Borovski
Felipe De Sousa E Melo
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectstem cell nicheQ16729831
neoplastic stem cellsQ1638475
P304page(s)634-9
P577publication date2011-02-01
P1433published inCancer ResearchQ326097
P1476titleCancer stem cell niche: the place to be
P478volume71

Reverse relations

cites work (P2860)
Q359945483D tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and radiation
Q34500627A 41-gene signature derived from breast cancer stem cells as a predictor of survival
Q50318144A Simple 3-Parameter Model for Cancer Incidences
Q90590032A novel model of liver cancer stem cells developed from induced pluripotent stem cells
Q92543800A novel reporter construct for screening small molecule inhibitors that specifically target self-renewing cancer cells
Q28486414A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept
Q33577624A unified model of the hierarchical and stochastic theories of gastric cancer
Q34251174ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice
Q37639483Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor.
Q37006135Acidic extracellular pH of tumors induces octamer-binding transcription factor 4 expression in murine fibroblasts in vitro and in vivo
Q42729198Activity of cytokine-induced killer cells against bone and soft tissue sarcoma
Q37266548Aiming to immune elimination of ovarian cancer stem cells
Q28534236Aldehyde dehydrogenase 1 identifies cells with cancer stem cell-like properties in a human renal cell carcinoma cell line
Q90647900An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment
Q90455008Anchorage-dependent multicellular aggregate formation induces a quiescent stem-like intractable phenotype in pancreatic cancer cells
Q39264002Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses
Q36064793Arsenic-transformed malignant prostate epithelia can convert noncontiguous normal stem cells into an oncogenic phenotype
Q37580275Autocrine glutamatergic transmission for the regulation of embryonal carcinoma stem cells
Q37689058Autocrine interleukin-23 promotes self-renewal of CD133+ ovarian cancer stem-like cells
Q38800430Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism.
Q91622832BRCA1 regulates the cancer stem cell fate of breast cancer cells in the context of hypoxia and histone deacetylase inhibitors
Q39279276Biliary tract cancer stem cells - translational options and challenges.
Q38035206CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges
Q34468655CD133+ and Nestin+ Glioma Stem-Like Cells Reside Around CD31+ Arterioles in Niches that Express SDF-1α, CXCR4, Osteopontin and Cathepsin K.
Q38922806CD133, Stem Cells, and Cancer Stem Cells: Myth or Reality?
Q36262890CD44 variant 6 is correlated with peritoneal dissemination and poor prognosis in patients with advanced epithelial ovarian cancer
Q90452178Can Stemness and Chemoresistance Be Therapeutically Targeted via Signaling Pathways in Ovarian Cancer?
Q27022017Can nanomedicines kill cancer stem cells?
Q36763883Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features.
Q38707592Cancer Stem Cells: Plasticity Works against Therapy
Q38724218Cancer Stem cells and their cellular origins in primary liver and biliary tract cancers
Q37712209Cancer cell dormancy in novel mouse models for reversible pancreatic cancer: a lingering challenge in the development of targeted therapies
Q38239661Cancer stem cell immunology: key to understanding tumorigenesis and tumor immune escape?
Q39113924Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells
Q26747144Cancer stem cells (CSCs), cervical CSCs and targeted therapies
Q38472322Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies
Q37288044Cancer stem cells as a potential therapeutic target in thyroid carcinoma
Q42330818Cancer stem cells don't waste their time cleaning-low proteasome activity, a marker for cancer stem cell function
Q38639008Cancer stem cells in laryngeal cancer: what we know.
Q26766132Cancer stem cells: Radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments
Q38950219Cancer stem cells: Role in tumor growth, recurrence, metastasis, and treatment resistance
Q38062840Cancer stem cells: the 'heartbeat' of gastric cancer
Q86523719Cancer stem cells: the challenges ahead
Q38034167Cancerous ovarian stem cells: obscure targets for therapy but relevant to chemoresistance.
Q36562747Cell budding from normal appearing epithelia: a predictor of colorectal cancer metastasis?
Q34200211Cellular phenotype-dependent and -independent effects of vitamin C on the renewal and gene expression of mouse embryonic fibroblasts
Q35971721Challenges in cancer molecular targets and therapeutics.
Q35058046Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary note
Q30843748Chitosan promotes cancer progression and stem cell properties in association with Wnt signaling in colon and hepatocellular carcinoma cells
Q61806531Collective radioresistance of T47D breast carcinoma cells is mediated by a Syncytin-1 homologous protein
Q33836972Colorectal adenoma stem-like cell populations: associations with adenoma characteristics and metachronous colorectal neoplasia
Q35772708Concise Review: Targeting Cancer Stem Cells Using Immunologic Approaches
Q39394303Current understanding of cancer stem cells: Review of their radiobiology and role in head and neck cancers
Q37499770DEspR roles in tumor vasculo-angiogenesis, invasiveness, CSC-survival and anoikis resistance: a 'common receptor coordinator' paradigm
Q49936710DJ-1 as a Therapeutic Target Against Cancer
Q42150992DNA damage responses in cancer stem cells: Implications for cancer therapeutic strategies
Q36284940Deciphering the Key Features of Malignant Tumor Microenvironment for Anti-cancer Therapy
Q26827732Defining stem cell types: understanding the therapeutic potential of ESCs, ASCs, and iPS cells
Q26864497Desmoplasia and chemoresistance in pancreatic cancer
Q39102930Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle
Q35053270Differential effects of drugs targeting cancer stem cell (CSC) and non-CSC populations on lung primary tumors and metastasis
Q97543194Dissecting and rebuilding the glioblastoma microenvironment with engineered materials
Q38955517Drugs in early clinical development for the treatment of osteosarcoma
Q38725554Emerging importance of dietary phytochemicals in fight against cancer: Role in targeting cancer stem cells
Q41329894Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells
Q47879589Endothelial Cells Promote Formation of Medulloblastoma Stem-Like Cells via Notch Pathway Activation.
Q34658803Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway
Q46509951Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.
Q34249060Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of Twist and the transforming growth factor β (TGF-β)-Snail signaling axis
Q28553738Expression of Cell-Surface Marker ABCB5 Causes Characteristic Modifications of Glucose, Amino Acid and Phospholipid Metabolism in the G3361 Melanoma-Initiating Cell Line
Q89769212Extracellular matrix as a driver of progressive fibrosis
Q64075384Facets of Communication: Gap Junction Ultrastructure and Function in Cancer Stem Cells and Tumor Cells
Q38786707From tumour heterogeneity to advances in precision treatment of colorectal cancer
Q27002840Gastric cancer stem cells: a novel therapeutic target
Q41571715Gefitinib-loaded DSPE-PEG2000 nanomicelles with CD133 aptamers target lung cancer stem cells
Q37269596Glioma stem cells enhance endothelial cell migration and proliferation via the Hedgehog pathway
Q36212296Head and Neck Cancer Stem Cells: From Identification to Tumor Immune Network
Q37936020Head and neck cancer stem cells
Q92442197Hematopoietic Cells Derived from Cancer Stem Cells Generated from Mouse Induced Pluripotent Stem Cells
Q36165598Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche
Q93112956Heterogeneity of Mesenchymal Stromal Cells in Myelodysplastic Syndrome-with Multilineage Dysplasia (MDS-MLD)
Q37675939High Infiltration of Polarized CD163+ Tumor-Associated Macrophages Correlates with Aberrant Expressions of CSCs Markers, and Predicts Prognosis in Patients with Recurrent Gastric Cancer
Q38097519Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy
Q48264446How the growth rate of host cells affects cancer risk in a deterministic way.
Q42152209Hypothesis about Transdifferentiation As Backbone of Malignancy
Q38924905Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells.
Q35066326Hypoxia-shaped vascular niche for cancer stem cells
Q38918537Hypoxic Microenvironment Induces EMT and Upgrades Stem-Like Properties of Gastric Cancer Cells
Q39727803IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence
Q90288485Identification of a stemness-related gene panel associated with BET inhibition in triple negative breast cancer
Q35410105Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib
Q27025151Identifying new small molecule anti-invasive compounds for glioma treatment
Q38416836Imaging Early Fate of Cancer Stem Cells in Mouse Hindlimbs with Sodium Iodide Symporter Gene and I-124 PET.
Q27324507Imaging of Angiotropism/Vascular Co-Option in a Murine Model of Brain Melanoma: Implications for Melanoma Progression along Extravascular Pathways.
Q41078974Impact of extracellular alkalinization on the survival of human CD24-/CD44+ breast cancer stem cells associated with cellular metabolic shifts
Q104111290Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells
Q38799821Induction of protumoral CD11c(high) macrophages by glioma cancer stem cells through GM-CSF.
Q38197931Interaction between gastric cancer stem cells and the tumor microenvironment
Q54969376Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness.
Q97067035Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies
Q39095733Interrogating open issues in cancer precision medicine with patient-derived xenografts.
Q53275437Intratumoral heterogeneity in the self-renewal and tumorigenic differentiation of ovarian cancer.
Q64075548Iron Metabolism in Liver Cancer Stem Cells
Q98289965Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway
Q90443148It's Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
Q34328494Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling
Q44357715Low probability activation of Bax/Bak can induce selective killing of cancer cells by generating heterogeneity in apoptosis
Q52087016Lung cancer-associated brain metastasis: Molecular mechanisms and therapeutic options.
Q57296952MDA-MB-231 Breast Cancer Cells and Their CSC Population Migrate Towards Low Oxygen in a Microfluidic Gradient Device
Q47224069Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway.
Q46265960Management and potentialities of primary cancer cultures in preclinical and translational studies
Q64993228Mechanobiology of Cancer Stem Cells and Their Niche.
Q27007499Mesenchymal stem cell secretome and regenerative therapy after cancer
Q36163766Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism
Q37420604Microenvironmental Niches and Sanctuaries: A Route to Acquired Resistance
Q26860238Midbody: from cellular junk to regulator of cell polarity and cell fate
Q38807462Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration
Q46362794Model of vascular desmoplastic multispecies tumor growth
Q35719210Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells
Q59795056Molecular Mechanisms Governing the Stem Cell's Fate in Brain Cancer: Factors of Stemness and Quiescence
Q33635399Molecular culprits generating brain tumor stem cells
Q38931516Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging
Q37687326Multi-cycle chemotherapy with the glycolipid-like polymeric micelles evade cancer stem cell enrichment in breast cancer therapy
Q47161788NRAS destines tumor cells to the lungs
Q38324456Nanocarrier-mediated drugs targeting cancer stem cells: an emerging delivery approach
Q37955957Nanoparticle mediated targeting of VEGFR and cancer stem cells for cancer therapy
Q39125508Neoplasms in the bone marrow niches: disturbance of the microecosystem
Q26771894New Findings on Breast Cancer Stem Cells: A Review
Q39363673Niche construction game cancer cells play
Q35073159Niche-dependent gene expression profile of intratumoral heterogeneous ovarian cancer stem cell populations
Q34499490Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen.
Q61805196Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells
Q52522309On-slide detection of enzymatic activities in selected single cells.
Q40697271Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment.
Q26741215Pancreatic cancer stem cell markers and exosomes - the incentive push
Q26863365Pancreatic cancer stem cells: emerging target for designing novel therapy
Q47235352Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins
Q38030287Perivascular stem cell niche in head and neck cancer
Q47105970Phenotypic heterogeneity in modeling cancer evolution.
Q92005572Photodynamic therapy of cervical cancer by eradication of cervical cancer cells and cervical cancer stem cells
Q38967602Potential effect of matrix stiffness on the enrichment of tumor initiating cells under three-dimensional culture conditions
Q37564113Pro-inflammatory-Related Loss of CXCL12 Niche Promotes Acute Lymphoblastic Leukemic Progression at the Expense of Normal Lymphopoiesis
Q34205351Proliferation and enrichment of CD133(+) glioblastoma cancer stem cells on 3D chitosan-alginate scaffolds
Q38668605Prostate cancer stem cells: from theory to practice.
Q58092065Reciprocal reprogramming of cancer cells and associated Mesenchymal Stem Cells in gastric cancer
Q37072641Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen.
Q37513688Regulation of stem cell populations by microRNAs
Q30526491Remnant living cells that escape cell loss in late-stage tumors exhibit cancer stem cell-like characteristics
Q58709905Replacement and desmoplastic histopathological growth patterns: A pilot study of prediction of outcome in patients with uveal melanoma liver metastases
Q92875468Role of Cancer Stem Cells in Cholangiocarcinoma and Therapeutic Implications
Q57596254Role of Cancer Stem Cells in Metastasis
Q38137820Role of Hippo signaling in cancer stem cells.
Q98184212Roniciclib down-regulates stemness and inhibits cell growth by inducing nucleolar stress in neuroblastoma
Q91741027STOCHASTIC DYNAMICS OF CELL LINEAGE IN TISSUE HOMEOSTASIS
Q91809243SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets
Q36346439SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity.
Q36891437Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
Q90361446Similarities Between Stem Cell Niches in Glioblastoma and Bone Marrow: Rays of Hope for Novel Treatment Strategies
Q35023931Spherical cancer models in tumor biology
Q48860154Stem Cell Plasticity and Niche Dynamics in Cancer Progression
Q38038562Stem cell bioengineering at the interface of systems-based models and high-throughput platforms
Q26746223Stem cell technology in breast cancer: current status and potential applications
Q28079205Stem-like plasticity and heterogeneity of circulating tumor cells: current status and prospect challenges in liver cancer
Q33572252Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment.
Q44484616Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro
Q41463557Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer.
Q39321673Targeting Lung Cancer Stem Cells: Research and Clinical Impacts
Q38149736Targeting cancer stem cells to suppress acquired chemotherapy resistance
Q64101613The Carcinogenic Role of the Notch Signaling Pathway in the Development of Hepatocellular Carcinoma
Q38006838The Eph/Ephrin family in cancer metastasis: communication at the service of invasion
Q91828615The Exosome And Breast Cancer Cell Plasticity
Q90066925The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance
Q46553742The PI3K/AKT/c-MYC Axis Promotes the Acquisition of Cancer Stem-Like Features in Esophageal Squamous Cell Carcinoma
Q57584305The Role of Biomaterials on Cancer Stem Cell Enrichment and Behavior
Q90179401The Role of Cancer Stem Cells in Radiation Resistance
Q92856177The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance
Q39407264The Role of Skeletal Stem Cells in the Reconstruction of Bone Defects
Q26824147The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?
Q37909375The clinical and therapeutic implications of cancer stem cell biology
Q35107800The culture of cancer cell lines as tumorspheres does not systematically result in cancer stem cell enrichment
Q37980960The developing cancer stem-cell model: clinical challenges and opportunities
Q38896944The hypoxic microenvironment: A determinant of cancer stem cell evolution
Q36187755The mesenchymal tumor microenvironment: a drug-resistant niche
Q38018809The metastatic niche and stromal progression
Q38287226The molecular mechanisms underlying the therapeutic resistance of cancer stem cells
Q35070157The role of breast cancer stem cells in metastasis and therapeutic implications
Q38961276The role of stem cells in benign tumors
Q37583296The roles of FOXM1 in pancreatic stem cells and carcinogenesis
Q27687567The tumor microenvironment shapes hallmarks of mature B-cell malignancies
Q47284097The unveiling of the Warburg effect and the inscribed innovative approach to a radical non toxic anticancer therapy
Q64075525Therapeutic Targeting of Cancer Stem Cells: Integrating and Exploiting the Acidic Niche
Q38218018Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.
Q38041427Thyroid hormone actions in liver cancer
Q43258268Tracing and targeting cancer stem cells: New venture for personalized molecular cancer therapy
Q37269535Transcriptional regulation of tenascin-W by TGF-beta signaling in the bone metastatic niche of breast cancer cells
Q37548863Treatment of agarose-agarose RENCA macrobeads with docetaxel selects for OCT4(+) cells with tumor-initiating capability
Q33889185Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent
Q38584340Tumor Microenvironment Versus Cancer Stem Cells in Cholangiocarcinoma: Synergistic Effects?
Q38824383Tumor-Initiating Cells: Emerging Biophysical Methods of Isolation
Q37649057Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies.
Q54960614Tumor-associated macrophages recruited by periostin in intrahepatic cholangiocarcinoma stem cells.
Q39241435Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway
Q92800229Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies
Q55126311Understanding the biology of urothelial cancer metastasis.
Q87423481[Tumor pathophysiology]
Q36763148cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse
Q38836415iRGD-conjugated DSPE-PEG2000 nanomicelles for targeted delivery of salinomycin for treatment of both liver cancer cells and cancer stem cells
Q36580342β4 Integrin signaling induces expansion of prostate tumor progenitors

Search more.