Regulation of renal cell carcinoma cell proliferation, invasion and metastasis by connexin 32 gene

scientific article

Regulation of renal cell carcinoma cell proliferation, invasion and metastasis by connexin 32 gene is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1029118082
P356DOI10.1007/S00232-007-9020-5
P3181OpenCitations bibliographic resource ID1396427
P698PubMed publication ID17565422

P2093author name stringH Hagiwara
H Sato
T Yano
H Senba
Y Ohde
N Virgona
P2860cites workRegulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen speciesQ44270073
Down-Regulation of Connexin 32 Gene Expression through DNA Methylation in a Human Renal Cell Carcinoma CellQ44400129
Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of huQ44441901
Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cellsQ46598132
Negative growth control of renal cell carcinoma cell by connexin 32: possible involvement of Her-2.Q47271663
Expression of P-glycoprotein and multidrug resistance in renal cell carcinoma.Q54254455
Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesisQ74147687
Tumor-suppressive effect of connexin 32 in renal cell carcinoma from maintenance hemodialysis patientsQ78630779
Connexin 32 potentiates vinblastine-induced cytotoxicity in renal cell carcinoma cellsQ79448979
ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent mannerQ24293488
Induction of tight junctions in human connexin 32 (hCx32)-transfected mouse hepatocytes: connexin 32 interacts with occludinQ28139215
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylaseQ28302589
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stabilityQ29615945
Isolation and purification of gap junction channelsQ33237452
Biochemical, cellular, and pharmacological aspects of the multidrug transporterQ33636699
Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ionsQ33850321
Role of Src expression and activation in human cancerQ34103650
Structural and functional diversity of connexin genes in the mouse and human genomeQ34137753
ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial aciniQ34187916
Determinants of drug delivery and transport to solid tumorsQ34328553
Cadherin-6, a cell adhesion molecule specifically expressed in the proximal renal tubule and renal cell carcinomaQ34430889
Gap junctions as targets for cancer chemoprevention and chemotherapyQ35007606
Connexins and cancer.Q35059240
Dioxygenases as O2-dependent regulators of the hypoxic response pathwayQ36248284
Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF).Q36346473
Connexin 32 as an anti-invasive and anti-metastatic gene in renal cell carcinomaQ36610639
Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cellsQ37482990
Tumor promotion: models and assay systemsQ37593945
V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.Q38341587
Connexin 32 down-regulates the fibrinolytic factors in metastatic renal cell carcinoma cellsQ40351025
Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesisQ40377374
Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cellsQ40428389
Connexin32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell lineQ40443900
Cx32 formation and/or Cx32-mediated intercellular communication induces expression and function of tight junctions in hepatocytic cell lineQ40735661
Reduction of malignant phenotype of HEPG2 cell is associated with the expression of connexin 26 but not connexin 32.Q40778065
Gap junction function and cancer.Q40856354
Cell-cell communication and growth control of normal and cancer cells: evidence and hypothesisQ40877179
Endogenous and exogenous modulation of gap junctional intercellular communication: toxicological and pharmacological implicationsQ40919043
New functions for gap junctionsQ40952539
Role of connexin genes in growth controlQ41016565
Neoplastic phenotype of gap-junctional intercellular communication-deficient WB rat liver epithelial cells and its reversal by forced expression of connexin 32.Q41027670
Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype.Q41090544
Transfection of C6 glioma cells with connexin32: the effects of expression of a nonendogenous gap junction proteinQ41490509
Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function.Q41644938
Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasisQ41730288
Size limit of molecules permeating the junctional membrane channelsQ43457900
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectrenal cell carcinomaQ1164529
P1104number of pages5
P304page(s)17-21
P577publication date2007-03-01
P1433published inJournal of Membrane BiologyQ6295550
P1476titleRegulation of renal cell carcinoma cell proliferation, invasion and metastasis by connexin 32 gene
P478volume216

Reverse relations

cites work (P2860)
Q367344475-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene
Q42718282Age-dependent carcinogenic susceptibility in rat liver is related to potential of gap junctional intercellular communication
Q60938845Cancer Connectors: Connexins, Gap Junctions, and Communication
Q54454903Clinical significance of vascular endothelial growth factor and connexin43 for predicting pancreatic cancer clinicopathologic parameters.
Q24644982Connexin 32 increases the proliferative response of Schwann cells to neuregulin-1 (Nrg1)
Q36031173Connexin and pannexin channels in cancer.
Q37488508Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo
Q64915043Connexins and Gap Junctions in Cancer of the Urinary Tract.
Q21245510Connexins: a myriad of functions extending beyond assembly of gap junction channels
Q38303074Connexins: junctional and non-junctional modulators of proliferation
Q28080874Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death
Q46390138Endothelial connexin32 enhances angiogenesis by positively regulating tube formation and cell migration
Q35101972Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a
Q36403429Expression of connexin 32 and connexin 43 in acute myeloid leukemia and their roles in proliferation
Q90318334How does Helicobacter pylori cause gastric cancer through connexins: An opinion review
Q37722095Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis.
Q28571256Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity
Q52563269The Novel Roles of Connexin Channels and Tunneling Nanotubes in Cancer Pathogenesis.

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