| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1990PNAS...87.9426S |
| P356 | DOI | 10.1073/PNAS.87.23.9426 |
| P932 | PMC publication ID | 55178 |
| P698 | PubMed publication ID | 2251284 |
| P5875 | ResearchGate publication ID | 20905356 |
| P2093 | author name string | S Aoki | |
| H Mitsuya | |||
| S Broder | |||
| K Murakami | |||
| H Ford | |||
| J A Kelley | |||
| T Shirasaka | |||
| H Yoshioka | |||
| E Kojima | |||
| P2860 | cites work | 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro | Q24609215 |
| Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS | Q28262859 | ||
| Molecular targets for AIDS therapy | Q28323494 | ||
| Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV | Q28329208 | ||
| Cyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitro | Q28334680 | ||
| Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents | Q28335025 | ||
| The role of mononuclear phagocytes in HTLV-III/LAV infection | Q29618676 | ||
| Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay | Q29619255 | ||
| The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial | Q29620785 | ||
| Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT). | Q33444047 | ||
| Lipid solubility and drug penetration of the blood brain barrier | Q34052243 | ||
| Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex | Q34558599 | ||
| Strategies for antiviral therapy in AIDS. | Q38172146 | ||
| Response of human-immunodeficiency-virus-associated neurological disease to 3'-azido-3'-deoxythymidine | Q41343118 | ||
| Synthesis of the 2-chloro analogues of 3'-deoxyadenosine, 2',3'-dideoxyadenosine, and 2',3'-didehydro-2',3'-dideoxyadenosine as potential antiviral agents | Q42199295 | ||
| Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives | Q42211960 | ||
| The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro | Q42216582 | ||
| In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine | Q43471767 | ||
| Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection | Q44134576 | ||
| Sequence of a yeast DNA fragment containing a chromosomal replicator and the TRP1 gene | Q48413159 | ||
| Nucleophilic displacement of the trimethylammonio-group as a new route to fluoropurines | Q70735354 | ||
| Adenosine aminohydrolase. Binding and hydrolysis of 2-and 6-substituted purine ribonucleosides and 9-substituted adenine nucleosides | Q72252692 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 9426-30 | |
| P577 | publication date | 1990-12-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Lipophilic halogenated congeners of 2',3'-dideoxypurine nucleosides active against human immunodeficiency virus in vitro | |
| P478 | volume | 87 |
| Q74511154 | Absorption and intestinal metabolism of purine dideoxynucleosides and an adenosine deaminase-activated prodrug of 2',3'-dideoxyinosine in the mesenteric vein cannulated rat ileum |
| Q46006243 | Acute oral toxicity and liver oxidant/antioxidant stress of halogenated benzene, phenol, and diphenyl ether in mice: a comparative and mechanism exploration. |
| Q35341682 | Anti-AIDS drug development: challenges and strategies |
| Q35322871 | Antiretroviral therapy: reverse transcriptase inhibition |
| Q35114114 | Antiviral activities of isometric dideoxynucleosides of D- and L-related stereochemistry |
| Q40874319 | Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact. |
| Q35118261 | Antiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4(S)-(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol |
| Q36757759 | Central nervous system targeting of 2',3'-dideoxyinosine via adenosine deaminase-activated 6-halo-dideoxypurine prodrugs |
| Q35174403 | Correlations Between theIn VitroandIn VivoActivity of Anti-HIV Agents: Implications for Future Drug Deyelopment |
| Q33933498 | Development and optimization of anti-HIV nucleoside analogs and prodrugs: A review of their cellular pharmacology, structure-activity relationships and pharmacokinetics |
| Q35174341 | Development of Inhibitors of Reverse Transcriptase and Protease as Therapeutics Against HIV Infection |
| Q35331251 | Didanosine. A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection |
| Q43781834 | Enhanced oral bioavailability of 2'- beta-fluoro-2',3'-dideoxyadenosine (F-ddA) through local inhibition of intestinal adenosine deaminase |
| Q71575299 | Enhanced oral bioavailability of DDI after administration of 6-Cl-ddP, an adenosine deaminase-activated prodrug, to chronically catheterized rats |
| Q28378709 | In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine |
| Q39989119 | In vitro evaluation of experimental agents for anti-HIV activity |
| Q28318476 | In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations |
| Q48846114 | Localization of purine metabolizing enzymes in bovine brain microvessel endothelial cells: an enzymatic blood-brain barrier for dideoxynucleosides? |
| Q35115096 | Pharmacokinetics of dideoxypurine nucleoside analogs in plasma and cerebrospinal fluid of rhesus monkeys |
| Q36069767 | Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs |
| Q28377462 | Synthesis, lipophilicity and anti-HIV activity of a new brominated analog of zidovudine |
| Q33933489 | Transport, metabolism and elimination mechanisms of anti-HIV agents |