| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Arthur Weiss | Q25939202 |
| P2093 | author name string | Ravindra Majeti | |
| Zheng Xu | |||
| Michelle L Hermiston | |||
| P2860 | cites work | Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation | Q22254014 |
| Subcellular localization of intracellular protein tyrosine phosphatases in T cells | Q24273420 | ||
| CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling | Q24290848 | ||
| Profound block in thymocyte development in mice lacking p56lck | Q24298882 | ||
| Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells | Q24315982 | ||
| SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF | Q24548380 | ||
| Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases | Q28143793 | ||
| Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge | Q28257943 | ||
| Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha | Q28374431 | ||
| Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development | Q28510142 | ||
| Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor | Q28584997 | ||
| Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation | Q30168286 | ||
| Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase | Q30175917 | ||
| Positive and negative regulation of Src-family membrane kinases by CD45. | Q33720532 | ||
| Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition | Q33867251 | ||
| The role of lipid rafts in T cell antigen receptor (TCR) signalling | Q33867254 | ||
| Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases. | Q33867275 | ||
| Signal transduction by the TCR for antigen | Q33898927 | ||
| IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled | Q33941375 | ||
| The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function | Q34038092 | ||
| Lymphocytes with a complex: adapter proteins in antigen receptor signaling | Q34091330 | ||
| Selected glimpses into the activation and function of Src kinase | Q34103644 | ||
| Constitutive activation of Src family kinases in mouse embryos that lack Csk. | Q34366689 | ||
| Regulatory mechanisms for receptor protein tyrosine phosphatases | Q34466027 | ||
| How regulated protein translocation can produce switch-like responses | Q34485181 | ||
| Membrane domains and the immunological synapse: keeping T cells resting and ready. | Q34502851 | ||
| ITAMs versus ITIMs: striking a balance during cell regulation | Q34502855 | ||
| Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk). | Q36369138 | ||
| Thymic tumorigenesis induced by overexpression of p56lck | Q37505339 | ||
| A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. | Q39450030 | ||
| Inhibitory tyrosine protein kinase p50csk is associated with protein-tyrosine phosphatase PTP-PEST in hemopoietic and non-hemopoietic cells | Q41091636 | ||
| Chk, a Csk family tyrosine protein kinase, exhibits Csk-like activity in fibroblasts, but not in an antigen-specific T-cell line. | Q41134884 | ||
| Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk | Q41528266 | ||
| Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice | Q41547257 | ||
| Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. | Q41565952 | ||
| Evidence for monomeric and dimeric forms of CD45 associated with a 30-kDa phosphorylated protein | Q41608433 | ||
| An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity | Q46113259 | ||
| Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase | Q46161173 | ||
| A point mutation in PTPRC is associated with the development of multiple sclerosis | Q57338217 | ||
| Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk | Q57371851 | ||
| T cell activation induces rapid tyrosine phosphorylation of a limited number of cellular substrates | Q69739741 | ||
| The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease | Q73606595 | ||
| The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck) | Q78162629 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | lymphocyte | Q715347 |
| P304 | page(s) | 9-14 | |
| P577 | publication date | 2002-01-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases | |
| P478 | volume | 109 |
| Q34811491 | A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4. |
| Q35011131 | A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs). |
| Q37150264 | A mechanism for SRC kinase-dependent signaling by noncatalytic receptors |
| Q24795134 | Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system |
| Q37370498 | Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus |
| Q35589667 | Alternative RNA splicing and cancer |
| Q39372815 | Alternative splicing networks regulated by signaling in human T cells. |
| Q37397652 | Antigen receptor signaling in the rheumatic diseases |
| Q46466021 | Association between the expression of IL-10 and T cell activation proteins loss in early breast cancer patients |
| Q24295854 | Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration |
| Q34652368 | BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling |
| Q24795003 | Basal immunoglobulin signaling actively maintains developmental stage in immature B cells |
| Q28278205 | CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts |
| Q34963679 | CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells |
| Q33370235 | Cellular phosphatases facilitate combinatorial processing of receptor-activated signals |
| Q40100408 | Combinatorial control of signal-induced exon repression by hnRNP L and PSF. |
| Q33639866 | Context-dependent regulatory mechanism of the splicing factor hnRNP L. |
| Q37877384 | Degrade, move, regroup: signaling control of splicing proteins |
| Q60582079 | Environmental influences on RNA processing: Biochemical, molecular and genetic regulators of cellular response |
| Q34528296 | Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy |
| Q45097366 | Expression of the peripheral benzodiazepine receptor triggers thymocyte differentiation. |
| Q30164830 | Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells |
| Q38174765 | Genomics of alternative splicing: evolution, development and pathophysiology |
| Q28584820 | Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development |
| Q36881697 | Host resistance and immune responses in advanced age. |
| Q40679291 | Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics. |
| Q37017265 | Immunosupportive therapies in aging |
| Q37625317 | Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling |
| Q35131486 | Lck regulates the threshold of activation in primary T cells, while both Lck and Fyn contribute to the magnitude of the extracellular signal-related kinase response |
| Q28288732 | Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts |
| Q34502851 | Membrane domains and the immunological synapse: keeping T cells resting and ready. |
| Q24799849 | Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system |
| Q90537292 | Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells |
| Q34018889 | Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation |
| Q24302148 | Phosphorylation-Dependent Regulation of PSF by GSK3 Controls CD45 Alternative Splicing |
| Q27021151 | Prostaglandin E2 and T cells: friends or foes? |
| Q41881723 | Protein tyrosine phosphatase non-receptor type 22 gene polymorphism C1858T is not associated with leprosy in Azerbaijan, Northwest Iran |
| Q24564615 | Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer |
| Q39989460 | Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus |
| Q24301383 | Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts |
| Q52689527 | Regulation of T-Cell Signaling by Post-Translational Modifications in Autoimmune Disease. |
| Q35176371 | Regulation of hematopoietic cell development and activation by adapter proteins |
| Q30164012 | Regulation of the Src family kinase Lck by Hsp90 and ubiquitination |
| Q33754402 | RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling |
| Q28741003 | Role of protein tyrosine phosphatases in cancer |
| Q83117322 | Signalling during hypoxia in human T lymphocytes--critical role of the src protein tyrosine kinase p56Lck in the O2 sensitivity of Kv1.3 channels |
| Q30493983 | Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells |
| Q36430287 | Synthetic multivalent ligands as probes of signal transduction |
| Q21245890 | Systematic identification of regulatory proteins critical for T-cell activation |
| Q35860040 | T-lymphocyte signalling in systemic lupus erythematosus: a lipid raft perspective |
| Q21090492 | The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells |
| Q54308180 | The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model. |
| Q38311601 | Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells |
| Q41226829 | hnRNP L and hnRNP A1 induce extended U1 snRNA interactions with an exon to repress spliceosome assembly |
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