| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Samson T Jacob | |
| Tasneem Motiwala | |||
| P2860 | cites work | Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1 | Q22009966 |
| PTPROt: an alternatively spliced and developmentally regulated B-lymphoid phosphatase that promotes G0/G1 arrest | Q22010571 | ||
| Translating the Histone Code | Q22065840 | ||
| A phosphotyrosine displacement mechanism for activation of Src by PTPalpha | Q22253266 | ||
| Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73 | Q24302209 | ||
| Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo | Q24311296 | ||
| Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density | Q24324756 | ||
| Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21 | Q24561369 | ||
| Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer | Q24564615 | ||
| Tyrosine kinase - Role and significance in Cancer. | Q24791430 | ||
| Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design | Q27748273 | ||
| PTEN and myotubularin: novel phosphoinositide phosphatases | Q27937321 | ||
| HD-PTP: A novel protein tyrosine phosphatase gene on human chromosome 3p21.3 | Q28138743 | ||
| Signaling to chromatin through histone modifications | Q28142598 | ||
| The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP | Q28145888 | ||
| Oncogenic kinase signalling | Q28189493 | ||
| Nitric oxide-induced inhibition of aortic smooth muscle cell motility: role of PTP-PEST and adaptor proteins p130cas and Crk | Q28201060 | ||
| Protein tyrosine phosphatase genes downregulated in melanoma | Q28205715 | ||
| Synthesis and biological activity of a novel class of pyridazine analogues as non-competitive reversible inhibitors of protein tyrosine phosphatase 1B (PTP1B). | Q40714214 | ||
| Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes | Q40721131 | ||
| Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias : combination analysis with cDNA expression array and tissue microarray | Q40777171 | ||
| Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation | Q40784834 | ||
| Leukocyte common antigen-related tyrosine phosphatase receptor: increased expression and neuronal-type splicing in breast cancer cells and tissue | Q40809922 | ||
| Expression of protein tyrosine phosphatases and its significance in esophageal cancer | Q40879139 | ||
| Both HPV and carcinogen contribute to the development of resistance to apoptosis during oral carcinogenesis | Q40899917 | ||
| The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells | Q40993616 | ||
| The selective reduction in PTPdelta expression in hepatomas. | Q41051118 | ||
| The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells. | Q41167843 | ||
| Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. | Q41438658 | ||
| Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system | Q41734970 | ||
| Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia | Q41772799 | ||
| Insulin expression in livers of diabetic mice mediated by hydrodynamics-based administration | Q41848708 | ||
| Expression of Fas and Fas-related molecules in human hepatocellular carcinoma | Q43556897 | ||
| A nuclear protein tyrosine phosphatase induces shortening of G1 phase and increase in c-Myc protein level | Q43561718 | ||
| Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases | Q44108229 | ||
| Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas. | Q44220722 | ||
| In vivo correction of murine tyrosinemia type I by DNA-mediated transposition. | Q44260023 | ||
| An adenovirus carrying the rat protein tyrosine phosphatase eta suppresses the growth of human thyroid carcinoma cell lines in vitro and in vivo. | Q44319405 | ||
| Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells | Q44323339 | ||
| Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism | Q44504194 | ||
| Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease | Q44542243 | ||
| Expression of a structurally unique osteoclastic protein-tyrosine phosphatase is driven by an alternative intronic, cell type-specific promoter | Q44569156 | ||
| Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer | Q44652158 | ||
| A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells | Q44714283 | ||
| Protein tyrosine phosphatase epsilon activates Yes and Fyn in Neu-induced mammary tumor cells | Q44774251 | ||
| Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets | Q44826936 | ||
| Methylation of SHP1 gene and loss of SHP1 protein expression are frequent in systemic anaplastic large cell lymphoma | Q45022834 | ||
| An osteoclastic protein-tyrosine phosphatase may play a role in differentiation and activity of human monocytic U-937 cell-derived, osteoclast-like cells. | Q45050331 | ||
| Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas. | Q45182737 | ||
| Molecular cytogenetic evaluation of virus-associated and non-viral hepatocellular carcinoma: analysis of 26 carcinomas and 12 concurrent dysplasias | Q45740459 | ||
| Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements. | Q45855517 | ||
| Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer | Q45862956 | ||
| Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system | Q45879828 | ||
| Target-site preferences of Sleeping Beauty transposons. | Q45880767 | ||
| SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway | Q38344554 | ||
| Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells | Q38362451 | ||
| Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1). | Q39540211 | ||
| Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure | Q39675513 | ||
| Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis | Q40402337 | ||
| Identification of metastasis-associated genes in prostate cancer by genetic profiling of human prostate cancer cell lines | Q40437699 | ||
| PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis | Q40443869 | ||
| A novel mechanism for imatinib mesylate (STI571) resistance in CML cell line KT-1: role of TC-PTP in modulating signals downstream from the BCR-ABL fusion protein | Q40493222 | ||
| Antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and depsipeptide on Raji lymphoma cells. | Q40556982 | ||
| Expression and function of the receptor protein tyrosine phosphatase zeta and its ligand pleiotrophin in human astrocytomas | Q40604566 | ||
| Activated proliferation of B-cell lymphomas/leukemias with the SHP1 gene silencing by aberrant CpG methylation | Q40604741 | ||
| Aberrant methylation of the negative regulators RASSFIA, SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia. | Q46414243 | ||
| Therapy-related acute myeloid leukemia in a child with Noonan syndrome and clonal duplication of the germline PTPN11 mutation | Q46632829 | ||
| Functional involvement of PTP-U2L in apoptosis subsequent to terminal differentiation of monoblastoid leukemia cells | Q47724155 | ||
| Loss of heterozygosity at the familial RCC t(3;8) locus in most clear cell renal carcinomas | Q48069229 | ||
| Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn. | Q48203636 | ||
| Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. | Q53358479 | ||
| Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes in Barrett's adenocarcinoma. | Q53367270 | ||
| Protein tyrosine phosphatase epsilon increases the risk of mammary hyperplasia and mammary tumors in transgenic mice. | Q53415824 | ||
| Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA | Q53650118 | ||
| Cytogenetical assignment and physical mapping of the human R-PTP-kappa gene (PTPRK) to the putative tumor suppressor gene region 6q22.2-q22.3. | Q55067836 | ||
| Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530 | Q58134938 | ||
| Induction of p53 dependent apoptosis upon overexpression of a nuclear protein tyrosine phosphatase | Q58214636 | ||
| Overexpression of a nuclear protein tyrosine phosphatase increases cell proliferation | Q58214639 | ||
| Increased mRNA expression of the receptor-like protein tyrosine phosphatase α in late stage colon carcinomas | Q58451300 | ||
| The FHIT and PTPRG genes are deleted in benign proliferative breast disease associated with familial breast cancer and cytogenetic rearrangements of chromosome band 3p14 | Q71733958 | ||
| Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate | Q71973575 | ||
| Overexpression of the protein tyrosine phosphatase, nonreceptor type 6 (PTPN6), in human epithelial ovarian cancer | Q72297344 | ||
| Spontaneous down-regulation of Fas-associated phosphatase-1 may contribute to excessive apoptosis in myelodysplastic marrows | Q73021171 | ||
| Expression of protein tyrosine phosphatase alpha (RPTPalpha) in human breast cancer correlates with low tumor grade, and inhibits tumor cell growth in vitro and in vivo | Q73104360 | ||
| PTP LAR expression compared to prognostic indices in metastatic and non-metastatic breast cancer | Q73478305 | ||
| Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer | Q73803404 | ||
| Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation | Q74457509 | ||
| Hot spots for molecular genetic alterations in lung cancer | Q77801662 | ||
| In vivo expression of soluble Fas and FAP-1: possible mechanisms of Fas resistance in human hepatoblastomas | Q77976709 | ||
| Expression of the transmembrane protein tyrosine phosphatase RPTPalpha in human oral squamous cell carcinoma | Q77992927 | ||
| Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas | Q78109218 | ||
| Decitabine | Q79303700 | ||
| Gene copy number change events at chromosome 20 and their association with recurrence in gastric cancer patients | Q81383337 | ||
| Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers | Q28207853 | ||
| A role for receptor tyrosine phosphatase zeta in glioma cell migration | Q28209273 | ||
| Chromatin remodeling: nucleosomes bulging at the seams | Q28213296 | ||
| Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers | Q28213364 | ||
| Differential induction of glioblastoma migration and growth by two forms of pleiotrophin | Q28252154 | ||
| A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome 1q32.1 | Q28259555 | ||
| Germ-line and somatic PTPN11 mutations in human disease | Q28264474 | ||
| Cdc25 phosphatases and cancer | Q28278269 | ||
| Chromosomal localization of the protein tyrosine phosphatase G1 gene and characterization of the aberrant transcripts in human colon cancer cells | Q28285731 | ||
| Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer | Q28287018 | ||
| Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST | Q28295462 | ||
| Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases | Q28344656 | ||
| Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer | Q28362064 | ||
| 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal | Q28384242 | ||
| Cloning and expression of a protein-tyrosine-phosphatase | Q28577079 | ||
| High-resolution genome-wide mapping of transposon integration in mammals | Q28769896 | ||
| Induction of apoptosis in fibroblasts by c-myc protein | Q29614346 | ||
| Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer | Q29615066 | ||
| Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells | Q29617246 | ||
| FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. | Q31027511 | ||
| Human pancreatic cancer cells disable function of Fas receptors at several levels in Fas signal transduction pathway | Q31922520 | ||
| Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas | Q33193334 | ||
| Cell signaling by protein tyrosine phosphorylation | Q33724532 | ||
| Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells | Q33859413 | ||
| Reduced expression of protein tyrosine phosphatase gamma in lung and ovarian tumors | Q33865606 | ||
| Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas | Q33940349 | ||
| Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents | Q34115488 | ||
| Induction of apoptosis by stomach cancer-associated protein-tyrosine phosphatase-1. | Q34137296 | ||
| Novel tumor suppressor loci on 6q22-23 in primary central nervous system lymphomas | Q34178075 | ||
| Downregulation of stomach cancer-associated protein tyrosine phosphatase-1 (SAP-1) in advanced human hepatocellular carcinoma | Q34216777 | ||
| PTP-MEG2 is activated in polycythemia vera erythroid progenitor cells and is required for growth and expansion of erythroid cells | Q34222776 | ||
| Function analysis of estrogenically regulated protein tyrosine phosphatase gamma (PTPgamma) in human breast cancer cell line MCF-7. | Q34283941 | ||
| Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins | Q34289354 | ||
| Sleeping beauty transposition: biology and applications for molecular therapy | Q34294570 | ||
| Mutational analysis of the tyrosine phosphatome in colorectal cancers | Q34322220 | ||
| Sleeping beauty transposon-mediated gene therapy for prolonged expression | Q34442366 | ||
| Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy | Q34528296 | ||
| Gene repair and transposon-mediated gene therapy | Q34565709 | ||
| Chromatin remodeling enzymes: taming the machines. Third in review series on chromatin dynamics | Q34594432 | ||
| HDAC's at work: everyone doing their part | Q34671229 | ||
| 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy | Q34770609 | ||
| Low molecular weight protein tyrosine phosphatases: small, but smart. | Q34777984 | ||
| DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias. | Q35032147 | ||
| The function of the protein tyrosine phosphatase SHP-1 in cancer | Q35092309 | ||
| The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting | Q35100856 | ||
| Protein tyrosine phosphatase alpha (PTPalpha): a Src family kinase activator and mediator of multiple biological effects | Q35100861 | ||
| Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation | Q35146110 | ||
| Phosphatases in cell-matrix adhesion and migration | Q35542014 | ||
| Epigenetic targets in hematopoietic malignancies | Q35551110 | ||
| A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage | Q35626652 | ||
| Linking the epigenetic 'language' of covalent histone modifications to cancer | Q35670206 | ||
| Protein tyrosine phosphatases: strategies for distinguishing proteins in a family containing multiple drug targets and anti-targets | Q35743560 | ||
| Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter | Q35745808 | ||
| Reversal of gene silencing as a therapeutic target for cancer--roles for DNA methylation and its interdigitation with chromatin | Q35788665 | ||
| Histones and histone modifications | Q35842800 | ||
| Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells | Q35847802 | ||
| Protein tyrosine phosphatases and signalling | Q36092317 | ||
| Dual specificity protein phosphatases: therapeutic targets for cancer and Alzheimer's disease | Q36094604 | ||
| Antisense therapy for cancer | Q36133133 | ||
| Adeno-associated virus vectors: potential applications for cancer gene therapy | Q36165834 | ||
| Awakening gene therapy with Sleeping Beauty transposons | Q36220906 | ||
| Linking covalent histone modifications to epigenetics: the rigidity and plasticity of the marks | Q36238549 | ||
| Innovative approaches to the clinical development of DNA methylation inhibitors as epigenetic remodeling drugs | Q36279318 | ||
| Clinical development of decitabine as a prototype for an epigenetic drug program | Q36279322 | ||
| Drug insight: Histone deacetylase inhibitors--development of the new targeted anticancer agent suberoylanilide hydroxamic acid | Q36303956 | ||
| Insertional mutagenesis of the Drosophila genome with single P elements | Q36312073 | ||
| Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression | Q36757232 | ||
| Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning. | Q38342926 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 297-329 | |
| P577 | publication date | 2006-01-01 | |
| P1433 | published in | Progress in Molecular Biology and Translational Science | Q15753415 |
| P1476 | title | Role of protein tyrosine phosphatases in cancer | |
| P478 | volume | 81 |
| Q33775528 | Aberrant PTPRO methylation in tumor tissues as a potential biomarker that predicts clinical outcomes in breast cancer patients |
| Q35891112 | Blockade of dual-specificity phosphatase 28 decreases chemo-resistance and migration in human pancreatic cancer cells |
| Q26863333 | Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor |
| Q37106891 | Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity |
| Q54275612 | Expression and clinical significance of SHP2 in gastric cancer. |
| Q40180313 | Expression and prognosis value of SHP2 in patients with pancreatic ductal adenocarcinoma |
| Q58736397 | Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients |
| Q90179514 | Label-Free Assay of Protein Tyrosine Phosphatase Activity in Single Cells |
| Q33952692 | Lyn kinase and ZAP70 are substrates of PTPROt in B-cells: Lyn inactivation by PTPROt sensitizes leukemia cells to VEGF-R inhibitor pazopanib |
| Q24619893 | Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia |
| Q34349289 | Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate |
| Q39569628 | PTP1B expression contributes to gastric cancer progression |
| Q37828546 | PTPN13/PTPL1: an important regulator of tumor aggressiveness |
| Q89184688 | PTPN6 regulates the cell-surface expression of TRPM4 channels in HEK293 cells |
| Q39919462 | PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells |
| Q44038757 | Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case-Control Study in Inner Mongolia, China |
| Q24612533 | Tumour suppressor function of protein tyrosine phosphatase receptor-T |
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