Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn.

scientific article published in May 1999

Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0960-9822(99)80238-3
P8608Fatcat IDrelease_bgawktxyprfl7cglsttanoc4e4
P698PubMed publication ID10339428

P50authorCatherine J. PallenQ42859967
P2093author name stringLim KL
Wang DZ
Ponniah S
P2860cites workPhysical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fynQ24322293
Cloning and expression of a widely expressed receptor tyrosine phosphataseQ24557510
Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphataseQ28188457
Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphataseQ28246466
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-srcQ34580219
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.Q36793338
The when and how of Src regulationQ40487537
CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and developmentQ40661212
Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.Q41075059
Leukocyte common antigen-related phosphatase (LRP) gene structure: conservation of the genomic organization of transmembrane protein tyrosine phosphatasesQ48111716
pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cellsQ63226061
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)535-538
P577publication date1999-05-01
P1433published inCurrent BiologyQ1144851
P1476titleTargeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn.
P478volume9

Reverse relations

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Q34116130c-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin/Efs without altering the kinetics of ERK activation

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