Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells

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Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID1221780
P698PubMed publication ID11311127

P2093author name stringC Zhang
H Ma
Y Gong
D Chen
Z L Chen
C An
P2860cites workTransient Ca2+ changes in endothelial cells induced by low doses of reactive oxygen species: role of hydrogen peroxideQ73455609
Diabetic-induced endothelial dysfunction in rat aorta: role of hydroxyl radicalsQ73499505
Trichosanthin interacts with and enters cells via LDL receptor family membersQ73642439
Superoxide anion radical-triggered Ca2+ release from cardiac sarcoplasmic reticulum through ryanodine receptor Ca2+ channelQ74294152
Effect of trichosanthin an anti-leukemia protein on normal mouse spleen cellsQ74500813
Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugsQ77359861
DNA fragmentation and cell death mediated by T cell antigen receptor/CD3 complex on a leukemia T cell lineQ93527312
Trichosanthin, a potent HIV-1 inhibitor, can cleave supercoiled DNAin vitroQ24628330
Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptorsQ24671923
The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV-1 integraseQ28142047
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosisQ28250587
Biochemical characteristics of caspases-3, -6, -7, and -8Q28250824
Mechanisms and Functions of Cell DeathQ28261655
Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscleQ28583958
Caspases: enemies withinQ29547315
Calcium signalingQ29618093
GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineageQ33851013
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor toneQ34378188
Safety, activity, and pharmacokinetics of GLQ223 in patients with AIDS and AIDS-related complexQ34724499
Regulation of cellular calcium through signaling cross-talk involves an intricate interplay between the actions of receptors, G-proteins, and second messengersQ40412985
The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxinQ40421134
Mitochondrial decay in agingQ40437264
Apoptosis. Its significance in cancer and cancer therapyQ40739570
Calcium-dependent PAF-stimulated generation of reactive oxygen species in a human keratinocyte cell lineQ40948370
Role of oxygen free radicals in cancer developmentQ40960388
NADPH oxidase of neutrophilsQ40976674
Antioxidant and redox regulation of gene transcriptionQ40989720
Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosisQ41003504
Generation of reactive oxygen species in a human keratinocyte cell line: role of calciumQ41065033
Oxidants as stimulators of signal transductionQ41260199
Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signalingQ41363401
Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s).Q41718595
Oxygen radicals and signalingQ41750986
Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentrationQ43535256
Homology of trichosanthin and ricin A chainQ44518089
Neurological reactions in HIV-infected patients treated with trichosanthin.Q46202549
Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neuronsQ48157353
The safety and pharmacokinetics of GLQ223 in subjects with AIDS and AIDS-related complex: a phase I study.Q48852003
Induction of hydrogen peroxide production and Bax expression by caspase-3(-like) proteases in tyrosine kinase inhibitor-induced apoptosis in human small cell lung carcinoma cells.Q53896443
Effects of free oxygen radicals on Ca2+ release mechanisms in the sarcoplasmic reticulum of scallop (Pecten jacobaeus) adductor muscle.Q53965647
Shrinkage necrosis: a distinct mode of cellular death.Q54179855
A phase I/II study of trichosanthin treatment of HIV diseaseQ68382155
Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowiiQ69651660
Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stressQ69834894
[Treatment of malignant trophoblastic neoplasia with trichosanthin]Q70186430
Oxidation pathways for the intracellular probe 2',7'-dichlorofluoresceinQ72903152
P433issuePt 3
P407language of work or nameEnglishQ1860
P921main subjectchoriocarcinomaQ1076481
reactive oxygen speciesQ424361
P304page(s)653-61
P577publication date2001-05-01
P1433published inBiochemical JournalQ864221
P1476titleReactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells
P478volume355

Reverse relations

cites work (P2860)
Q28486683ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells
Q26864994Anti-tumor action of trichosanthin, a type 1 ribosome-inactivating protein, employed in traditional Chinese medicine: a mini review
Q42180926Arabidopsis Bax Inhibitor-1 inhibits cell death induced by pokeweed antiviral protein in Saccharomyces cerevisiae
Q51071237Balsamin induces apoptosis in breast cancer cells via DNA fragmentation and cell cycle arrest.
Q38352033CREB, a possible upstream regulator of Bcl-2 in trichosanthin-induced HeLa cell apoptosis
Q38725127DeBouganin Diabody Fusion Protein Overcomes Drug Resistance to ADCs Comprised of Anti-Microtubule Agents.
Q40538632Effect of extracts of trichosanthes root tubers on HepA-H cells and HeLa cells
Q90394569Engineering of Ribosome-inactivating Proteins for Improving Pharmacological Properties
Q33204844In vitro anti-coxsackievirus B(3) effect of ethyl acetate extract of Tian-hua-fen.
Q54631935Increase of cytosolic calcium induced by trichosanthin suppresses cAMP/PKC levels through the inhibition of adenylyl cyclase activity in HeLa cells.
Q39942947Induced apoptotic action of recombinant trichosanthin in human stomach adenocarcinoma MCG803 cells
Q33568201Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid
Q92879410Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
Q43256202Mechanism of the specific neuronal toxicity of a type I ribosome-inactivating protein, trichosanthin.
Q41918293Plant Ribosome-Inactivating Proteins: Progesses, Challenges and Biotechnological Applications (and a Few Digressions).
Q36308816Serum from rabbit orally administered cobra venom inhibits growth of implanted hepatocellular carcinoma cells in mice
Q58734587Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein
Q36728200The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3
Q36309105The sensitivity of digestive tract tumor cells to As2O3 is associated with the inherent cellular level of reactive oxygen species
Q37728221Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancer model by boosting the interaction between TSLC1 and CRTAM.
Q50318305Trichosanthin enhances sensitivity of non-small cell lung cancer (NSCLC) TRAIL-resistance cells.
Q28483437Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis
Q36490298Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway

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