| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0002-9440(10)64675-5 |
| P8608 | Fatcat ID | release_ejhnnidubfenjndkf4ga3p6wrq |
| P3181 | OpenCitations bibliographic resource ID | 4781928 |
| P932 | PMC publication ID | 1891970 |
| P698 | PubMed publication ID | 11395381 |
| P2093 | author name string | M R D'Andrea | |
| P Andrade-Gordon | |||
| C K Derian | |||
| R J Santulli | |||
| P2860 | cites work | Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2 | Q24309500 |
| Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1 | Q24309637 | ||
| Thrombin receptor overexpression in malignant and physiological invasion processes | Q24323035 | ||
| Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2 | Q24336125 | ||
| Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation | Q24337851 | ||
| The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells | Q24562218 | ||
| Molecular cloning of a potential proteinase activated receptor | Q24563694 | ||
| Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility | Q30471919 | ||
| Molecular cloning of the rat vascular smooth muscle thrombin receptor. Evidence for in vitro regulation by basic fibroblast growth factor | Q30984087 | ||
| The role of stroma in breast carcinoma growth in vivo | Q33923789 | ||
| Solid tumor cells express functional "tethered ligand" thrombin receptor. | Q34317063 | ||
| Interactions of mast cell tryptase with thrombin receptors and PAR-2. | Q34415372 | ||
| Characterization of protease-activated receptor-2 immunoreactivity in normal human tissues | Q34454176 | ||
| Enhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor-activating peptides | Q35601886 | ||
| Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin | Q35943993 | ||
| Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor | Q36530923 | ||
| Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation | Q36618743 | ||
| Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis | Q37370158 | ||
| Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. | Q37821791 | ||
| The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells | Q40342271 | ||
| The role of thrombin in tumor cell metastasis | Q40472721 | ||
| Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity | Q40628941 | ||
| Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium | Q40923257 | ||
| A human prostatic stromal myofibroblast cell line WPMY-1: a model for stromal-epithelial interactions in prostatic neoplasia | Q40945599 | ||
| Cellular consequences of thrombin-receptor activation | Q40952373 | ||
| Proteinase-activated receptor-2-mediated signaling and inhibition of DNA synthesis in human pancreatic cancer cells | Q40994701 | ||
| Protease-mediated signalling: new paradigms for cell regulation and drug development | Q41098006 | ||
| The role of fibroblasts in tumor behavior | Q41121042 | ||
| Human mast cells activate fibroblasts: tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis. | Q41125883 | ||
| Trypsinogen expression in human ovarian carcinomas | Q41283685 | ||
| The role of transforming growth factor beta 1 in the fibroblastic reaction associated with rat colorectal tumor development | Q41410521 | ||
| Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line | Q41437645 | ||
| Thrombin stimulates fibroblast chemotaxis and replication | Q41551367 | ||
| The role of protease-activated receptor-2 (PAR2) in the modulation of beating of the mouse isolated ureter: lack of involvement of mast cells or sensory nerves | Q41791288 | ||
| A prothrombinase complex of mouse peritoneal macrophages | Q43440357 | ||
| Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo | Q46286760 | ||
| Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration | Q48543950 | ||
| Altered vascular injury responses in mice deficient in protease-activated receptor-1. | Q50515256 | ||
| A combined histochemical and double immunohistochemical labeling protocol for simultaneous evaluation of four cellular markers in restenotic arteries. | Q50515900 | ||
| Multiple secretion of matrix serine proteinases by human gastric carcinoma cell lines | Q67901729 | ||
| Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen | Q68198443 | ||
| Presence of the seven transmembrane thrombin receptor on human tumour cells: effect of activation on tumour adhesion to platelets and tumor tyrosine phosphorylation | Q71005097 | ||
| Cellular localization of enzymatically active thrombin in intact human tissues by hirudin binding | Q71543614 | ||
| Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family | Q71734019 | ||
| Thrombin increases the metastatic potential of tumor cells | Q72086572 | ||
| Thrombin-induced degranulation of cultured bone marrow-derived mast cells | Q72748263 | ||
| The thrombin receptor | Q72792663 | ||
| Cytoskeletal and cytocontractile protein composition of smooth muscle cells in developing and obstructed rabbit bladder | Q72863988 | ||
| Smooth muscle myosin regulation by serum and cell density in cultured rat lung connective tissue cells | Q72917465 | ||
| Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2 | Q73382005 | ||
| Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2 | Q73441679 | ||
| Mechanisms involved in the early interaction between HeLa cells, platelets and endothelial cells in vitro under the influence of thrombin. Effects of acetylsalicylic acid and Na-salicylate | Q73454702 | ||
| Localization of protease-activated receptors-1 and -2 in human mast cells: indications for an amplified mast cell degranulation cascade | Q74168119 | ||
| Characterization of functional thrombin receptors in human pancreatic tumor cells (MIA PACA-2) | Q74336397 | ||
| Protease-activated receptor 1 (PAR-1) is required and rate-limiting for thrombin-enhanced experimental pulmonary metastasis | Q77531791 | ||
| Increased expression of protease activated receptor-2 (PAR-2) in balloon-injured rat carotid artery | Q77871834 | ||
| Coagulative properties of cancers | Q78381145 | ||
| On the mechanism of thrombin-induced angiogenesis: inhibition of attachment of endothelial cells on basement membrane components | Q79097186 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2031-41 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues | |
| P478 | volume | 158 |
| Q54577576 | A functional comparison of canine and murine bone marrow derived cultured mast cells. |
| Q35749110 | Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells |
| Q28512580 | Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis |
| Q35363647 | Activation of protease-activated receptors (PARs)-1 and -2 promotes alpha-smooth muscle actin expression and release of cytokines from human lung fibroblasts |
| Q33289128 | Analysis of protease-activated receptor-1 and -2 in human scar formation. |
| Q64989395 | Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease. |
| Q92803243 | Breast cancer stromal clotting activation (Tissue Factor and thrombin): A pre-invasive phenomena that is prognostic in invasion |
| Q36423991 | Characterization of PAR1 and FGFR1 expression in invasive breast carcinomas: Prognostic significance. |
| Q24810282 | Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts |
| Q40503317 | Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2. |
| Q41585571 | Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells |
| Q38746986 | Deregulated matriptase activity in oral squamous cell carcinoma promotes the infiltration of cancer-associated fibroblasts by paracrine activation of protease-activated receptor 2. |
| Q44126415 | Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein |
| Q40646901 | Enhanced Serine Palmitoyltransferase Expression in Proliferating Fibroblasts, Transformed Cell Lines, and Human Tumors |
| Q33614606 | Evaluation on potential contributions of protease activated receptors related mediators in allergic inflammation |
| Q35791283 | Expression of protease-activated receptor-1, -2, -3, and -4 in control and experimentally inflamed mouse bladder |
| Q81281892 | Expression of protease-activated receptors and tissue factor in human liver |
| Q37766499 | Expression of proteinase-activated receptor 1-4 (PAR 1-4) in human cancer |
| Q45224424 | Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer |
| Q34037992 | Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1). |
| Q40401241 | Human peripheral blood monocytes express protease receptor-2 and respond to receptor activation by production of IL-6, IL-8, and IL-1{beta}. |
| Q38712691 | Inhibitory effect of FSLLRY-NH2 on inflammatory responses induced by hydrogen peroxide in HepG2 cells |
| Q54517201 | Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors. |
| Q39792935 | Kallikrein-related peptidase-4 initiates tumor-stroma interactions in prostate cancer through protease-activated receptor-1. |
| Q35082007 | Mast cells in the pathogenesis of fibrosis |
| Q24816796 | Ovarian cancer, the coagulation pathway, and inflammation |
| Q27001552 | PAR-1 and thrombin: the ties that bind the microenvironment to melanoma metastasis |
| Q43053645 | PAR-2 regulates dental pulp inflammation associated with caries. |
| Q37246397 | PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study |
| Q44630306 | PAR2-induced inflammatory responses in human kidney tubular epithelial cells |
| Q36273274 | Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer. |
| Q36734061 | Potential physiological and pathophysiological roles for protease-activated receptor-2 in the kidney |
| Q85166333 | Prognostic Value of Protease-Activated Receptor 2 Expression in Oesophageal Squamous Cell Carcinoma |
| Q35684158 | Progress in the understanding of protease-activated receptors |
| Q40580473 | Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation |
| Q37286948 | Protease-activated receptor-1 is upregulated in reactive stroma of primary prostate cancer and bone metastasis |
| Q40067879 | Protease-activated receptor-2 (PAR-2) in cervical cancer proliferation. |
| Q40260379 | Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor receptor trans-activation and proliferation. |
| Q35107634 | Protease-activated receptors |
| Q36322931 | Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis. |
| Q64105617 | Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases |
| Q36121203 | Protease-activated receptors in cancer: A systematic review |
| Q35204291 | Protease-activated receptors in the Achilles tendon-a potential explanation for the excessive pain signalling in tendinopathy |
| Q37323621 | Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration |
| Q34770095 | Regulation of gene expression and inhibition of experimental prostate cancer bone metastasis by dietary genistein |
| Q35139963 | Resistance mechanisms of gastrointestinal cancers: why does conventional chemotherapy fail? |
| Q33378232 | Role of protease activated receptor-2 in lymph node metastasis of uterine cervical cancers |
| Q53255805 | Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis. |
| Q35170428 | Role of tissue stroma in cancer cell invasion |
| Q33818974 | Serine proteases and protease-activated receptor 2-dependent allodynia: a novel cancer pain pathway. |
| Q33745103 | Serum cellular apoptosis susceptibility protein is a potential prognostic marker for metastatic colorectal cancer |
| Q35056626 | Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo. |
| Q36334912 | Targeting the stromal fibroblasts: a novel approach to melanoma therapy |
| Q37591794 | Teleocidin A2 inhibits human proteinase-activated receptor 2 signaling in tumor cells |
| Q28290701 | The emerging roles of human tissue kallikreins in cancer |
| Q36511032 | The pathogenesis of venous thromboembolism in cancer: emerging links with tumour biology |
| Q34269077 | Thrombin and Phenotypic Modulation of the Endothelium |
| Q53652220 | Thrombin receptor expression is upregulated in prostate cancer. |
| Q38836736 | Thrombin-unique coagulation system protein with multifaceted impacts on cancer and metastasis. |
| Q79906656 | Tissue factor and PAR signaling in tumor progression |
| Q37903955 | Tissue factor and cell signalling in cancer progression and thrombosis |
| Q33726774 | Tissue factor-factor VIIa signaling |
| Q36476136 | Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. |
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