review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1002/PATH.1398 |
P698 | PubMed publication ID | 12845611 |
P2093 | author name string | Olivier De Wever | |
Marc Mareel | |||
P2860 | cites work | Structural basis for FGF receptor dimerization and activation | Q22010544 |
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7 | Q24299813 | ||
Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts | Q24303805 | ||
The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn) | Q24310022 | ||
Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells | Q24313011 | ||
Involvement of the tyrosine kinase fer in cell adhesion | Q24522716 | ||
HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers | Q24546185 | ||
Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway | Q24550898 | ||
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death | Q24563654 | ||
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Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways | Q24647244 | ||
The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1 | Q24673453 | ||
The nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage | Q24682886 | ||
Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion | Q24683255 | ||
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N-cadherin-mediated adhesion and aberrant catenin expression in anaplastic thyroid-carcinoma cell lines. | Q52536650 | ||
Cancer: stuck at first base. | Q53386975 | ||
Cyclosporine induces cancer progression by a cell-autonomous mechanism. | Q53426083 | ||
Metastasis is driven by sequential elevation of H-ras and Smad2 levels. | Q54297451 | ||
A juvenile polyposis tumor suppressor locus at 10q22 is deleted from nonepithelial cells in the lamina propria. | Q54568654 | ||
Chemotactic factors, passive invasion and metastasis of cancer cells | Q57584824 | ||
ONCOGENESIS: Landscaping the Cancer Terrain | Q57636195 | ||
An anchor for activation | Q58994527 | ||
Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1 | Q59066124 | ||
Myofibroblasts differentiate from fibroblasts when plated at low density | Q37633281 | ||
Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via the proteolytically activated receptor-1 and a protein kinase C-dependent pathway | Q38296390 | ||
Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach. | Q38302488 | ||
Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways | Q38307195 | ||
Inhibition of RhoA by p120 catenin | Q38525924 | ||
The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells | Q40342271 | ||
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells | Q40444996 | ||
Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation | Q40728276 | ||
Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly | Q40733139 | ||
Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion | Q40740891 | ||
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways | Q40757186 | ||
Single alteration of p53 or E-cadherin genes can alter the surgical resection benefit in an experimental model of colon cancer | Q40782283 | ||
Identification of Src phosphorylation sites in the catenin p120ctn | Q40802423 | ||
Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-beta1-dependent mechanism in vitro. | Q40818094 | ||
Induction of invasion in vivo of alpha-catenin-positive HCT-8 human colon-cancer cells | Q40843226 | ||
Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. | Q40897597 | ||
N-Cadherin expression in human prostate carcinoma cell lines. An epithelial-mesenchymal transformation mediating adhesion withStromal cells. | Q40928947 | ||
Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. | Q40968846 | ||
Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: evidence for a role of hepatocyte growth factor | Q41077052 | ||
Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease | Q41078715 | ||
TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis | Q41159403 | ||
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells | Q41164260 | ||
Role of stromal myofibroblasts infiltrating colon cancer in tumor invasion | Q41176300 | ||
CAM-FGF receptor interactions: a model for axonal growth | Q41212600 | ||
In vivo and in vitro invasiveness of a rat colon-cancer cell line maintaining E-cadherin expression: an enhancing role of tumor-associated myofibroblasts | Q41487536 | ||
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role | Q41674960 | ||
Mammalian RGS proteins: barbarians at the gate | Q41682826 | ||
Beta-catenin: a key mediator of Wnt signaling | Q41732761 | ||
Regulated binding of PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of beta-catenin | Q41863168 | ||
Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis | Q41909060 | ||
The compliance of collagen gels regulates transforming growth factor-beta induction of alpha-smooth muscle actin in fibroblasts | Q42275088 | ||
Pentoxifylline reduces in vitro renal myofibroblast proliferation and collagen secretion | Q42482695 | ||
Apigenin decreases expression of the myofibroblast phenotype | Q42511080 | ||
A novel family of cyclic peptide antagonists suggests that N-cadherin specificity is determined by amino acids that flank the HAV motif | Q42805775 | ||
Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo | Q42824510 | ||
MMP inhibitors augment fibroblast adhesion through stabilization of focal adhesion contacts and up-regulation of cadherin function | Q42826486 | ||
Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells | Q42831369 | ||
In fibroblasts Vegf-D expression is induced by cell-cell contact mediated by cadherin-11. | Q42833515 | ||
Transforming growth factor beta 1 and interleukin 4 induced alpha smooth muscle actin expression and myofibroblast-like differentiation in human synovial fibroblasts in vitro: modulation by basic fibroblast growth factor | Q43053651 | ||
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells | Q43107815 | ||
Ligands of peroxisome proliferator-activated receptor-gamma block activation of pancreatic stellate cells | Q43770515 | ||
Novel anti-inflammatory effects of the inhaled corticosteroid fluticasone propionate during lung myofibroblastic differentiation. | Q43775081 | ||
Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts. | Q43902871 | ||
Effects of transforming growth factor-beta1 and tumour necrosis factor-alpha on cultured fibroblasts from skin fibroma as modulated by toremifene. | Q43956031 | ||
Proximal tubular cells promote fibrogenesis by TGF-beta1-mediated induction of peritubular myofibroblasts | Q44004829 | ||
Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization | Q44049207 | ||
Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion | Q44164981 | ||
Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways | Q44165066 | ||
PTP1B modulates the association of beta-catenin with N-cadherin through binding to an adjacent and partially overlapping target site | Q44177992 | ||
Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta | Q44225473 | ||
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis. | Q44266290 | ||
Invasion of retinal pigment epithelial cells: N-cadherin, hepatocyte growth factor, and focal adhesion kinase | Q44295556 | ||
TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice | Q45345227 | ||
Mutations in the SMAD4/DPC4 gene in juvenile polyposis | Q45345229 | ||
ECM signalling: orchestrating cell behaviour and misbehaviour. | Q45971375 | ||
Human breast carcinoma desmoplasia is PDGF initiated. | Q46033815 | ||
TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis | Q46272247 | ||
Cadherin function is required for axon outgrowth in retinal ganglion cells in vivo. | Q46328098 | ||
Inhibitory effects of tranilast on expression of transforming growth factor-beta isoforms and receptors in injured arteries | Q47987270 | ||
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis | Q36316373 | ||
The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure | Q36324654 | ||
The nonreceptor tyrosine kinase fer mediates cross-talk between N-cadherin and beta1-integrins | Q36328276 | ||
Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta | Q36352371 | ||
N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility | Q36360384 | ||
Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions | Q36377967 | ||
The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness | Q36381379 | ||
Identification and characterization of a fibroblast marker: FSP1 | Q36382596 | ||
Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes | Q36672550 | ||
Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing | Q37359804 | ||
Human fetal enterocytes in vitro: modulation of the phenotype by extracellular matrix | Q37435596 | ||
Molecular themes in oncogenesis | Q37625792 | ||
PTPmu regulates N-cadherin-dependent neurite outgrowth | Q24685817 | ||
The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion. | Q24801456 | ||
Structural basis of cell-cell adhesion by cadherins | Q27730408 | ||
Epithelial-mesenchymal transitions in tumour progression | Q27860487 | ||
Angiogenesis in cancer and other diseases | Q27861015 | ||
Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing | Q28131793 | ||
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis | Q28137622 | ||
Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology | Q28138090 | ||
Receptor protein-tyrosine phosphatase RPTPmu binds to and dephosphorylates the catenin p120(ctn) | Q28141206 | ||
TGFbeta signaling in growth control, cancer, and heritable disorders | Q28142605 | ||
The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin | Q28145531 | ||
Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542 | Q28204648 | ||
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway | Q28240585 | ||
Functional interaction of beta-catenin with the transcription factor LEF-1 | Q28286884 | ||
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis | Q28359718 | ||
Identification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture model | Q28363408 | ||
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues | Q28366493 | ||
Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE) | Q28366662 | ||
Deactivation of cultured human liver myofibroblasts by trans-resveratrol, a grapevine-derived polyphenol | Q28374333 | ||
Thrombospondin-1 is a major activator of TGF-beta1 in vivo | Q28513856 | ||
Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro | Q28579283 | ||
The many faces of G protein signaling | Q28608944 | ||
Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells | Q28609640 | ||
Angiogenesis in cancer, vascular, rheumatoid and other disease | Q29547165 | ||
New functions for the matrix metalloproteinases in cancer progression | Q29547738 | ||
Metastasis to bone: causes, consequences and therapeutic opportunities | Q29614310 | ||
The distribution of secondary growths in cancer of the breast. 1889 | Q29614314 | ||
TGF-beta signaling in tumor suppression and cancer progression | Q29615427 | ||
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma | Q29615947 | ||
Marrow stromal cells as stem cells for nonhematopoietic tissues | Q29618770 | ||
The microenvironment of the tumour-host interface | Q29620375 | ||
Discovery of novel tumor markers of pancreatic cancer using global gene expression technology | Q31048088 | ||
p120 catenin regulates the actin cytoskeleton via Rho family GTPases | Q33180846 | ||
Effects of pentoxifylline, pentifylline and gamma-interferon on proliferation, differentiation, and matrix synthesis of human renal fibroblasts | Q33181128 | ||
Genetic events and the role of TGF beta in epithelial tumour progression | Q33643339 | ||
Mechanisms of myofibroblast activity and phenotypic modulation. | Q33691240 | ||
What might a stromal response mean to prostate cancer progression? | Q33715210 | ||
Evidence that metastasis is less common in cirrhotic than normal liver: a systematic review of post-mortem case-control studies. | Q33762474 | ||
FGFs, heparan sulfate and FGFRs: complex interactions essential for development | Q33828280 | ||
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging | Q33946993 | ||
Molecular mechanisms of cancer pain | Q33958925 | ||
Colorectal cancer—prognostic signs in “local disease” | Q34048121 | ||
The age of cancer | Q34088387 | ||
Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells | Q34094070 | ||
Transforming growth factor-beta activation in irradiated murine mammary gland | Q34128453 | ||
G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells | Q34130876 | ||
Regulation of Rho GTPases by p120-catenin | Q34360623 | ||
Defective E-cadherin/catenin complexes in human cancer | Q34491016 | ||
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo | Q34503877 | ||
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation | Q34527075 | ||
Lymphatic dissemination of tumour cells and the formation of micrometastases | Q34571762 | ||
Role of myofibroblasts at the invasion front | Q34584808 | ||
Vascular growth factors and lymphangiogenesis | Q34711216 | ||
Beta-catenin and the morphogenesis of colorectal cancer | Q34732468 | ||
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis | Q34790518 | ||
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. | Q34792468 | ||
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects | Q34792580 | ||
A reevaluation of integrins as regulators of angiogenesis | Q34805783 | ||
Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression | Q35065708 | ||
Clinical, cellular, and molecular aspects of cancer invasion | Q35094102 | ||
Differential expression of CD34 in normal colorectal tissue, peritumoral inflammatory tissue, and tumour stroma | Q35570992 | ||
Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis | Q35746891 | ||
Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation | Q35746896 | ||
Tumorigenic conversion of immortal human keratinocytes through stromal cell activation | Q35787577 | ||
Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasion | Q35788695 | ||
Expression of smooth muscle-specific proteins in myoepithelium and stromal myofibroblasts of normal and malignant human breast tissue | Q36085371 | ||
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion | Q36220888 | ||
Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin | Q36222838 | ||
TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors | Q36235100 | ||
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression | Q36294742 | ||
P433 | issue | 4 | |
P304 | page(s) | 429-447 | |
P577 | publication date | 2003-07-01 | |
P1433 | published in | Journal of Pathology | Q400296 |
P1476 | title | Role of tissue stroma in cancer cell invasion | |
P478 | volume | 200 |