Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

scientific article

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9440(10)62551-5
P932PMC publication ID1867224
P698PubMed publication ID11943709
P5875ResearchGate publication ID11422295

P50authorRalph H. HrubanQ21063634
Charles J YeoQ96191880
Raheela AshfaqQ114316683
N Tjarda van HeekQ114398786
Grace L Shen-OngQ114439494
Michael A. HollingsworthQ115598791
Christine A Iacobuzio-DonahueQ58327762
Anirban MaitraQ63019787
Michael GogginsQ63021511
P2093author name stringScott E Kern
John L Cameron
Karin Berg
Kimberly Walter
Renee Meyer
P2860cites workClaudin multigene family encoding four-transmembrane domain protein components of tight junction strandsQ22008687
CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cellsQ24291469
Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cellsQ28139134
Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activationQ28141319
cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like geneQ28144158
Cancer statistics, 2001Q28189339
The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesisQ28191029
Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing proteinQ28240208
Human Trop-2 is a tumor-associated calcium signal transducerQ28272535
Expression of the ATDC (ataxia telangiectasia group D-complementing) gene in A431 human squamous carcinoma cellsQ28280512
Expression of a candidate ataxia-telangiectasia group D gene in cultured fibroblast cell lines and human tissuesQ28287375
S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional rolesQ29620465
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).Q30781823
Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancerQ30809756
Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma.Q30991221
Relationships and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression.Q31037582
Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancerQ31833417
Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expressionQ33873179
cDNA cloning of a novel bHLH-PAS transcription factor superfamily gene, BMAL2: its mRNA expression, subcellular distribution, and chromosomal localizationQ33915836
Tumor therapy with targeted atomic nanogeneratorsQ34102138
AML1/CBFbeta transcription complex: its role in normal hematopoiesis and leukemiaQ34257991
Integrin signaling revisitedQ34446298
Location, location, location: membrane targeting directed by PX domainsQ34453921
Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer.Q34514616
Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasionQ35788695
Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancerQ35809752
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.Q40683219
Invasion-specific genes in malignancy: serial analysis of gene expression comparisons of primary and passaged cancers.Q40716089
Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell linesQ40783622
Reduction of transglutaminase 2 expression is associated with an induction of drug sensitivity in the PC-14 human lung cancer cell lineQ40962841
Cationic trypsinogen produced by human pancreatic ductal cancer has the characteristics of spontaneous activation and gelatinolytic activity in the presence of proton.Q40988497
Localization of GTPase-activating protein-(GAP) like immunoreactivity in mouse cerebral regionsQ42472692
Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.Q42818041
Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivationQ43719938
Retrovirus-mediated transfer of the herpes simplex virus thymidine kinase and connexin26 genes in pancreatic cells results in variable efficiency on the bystander killing: implications for gene therapyQ43773454
Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of the herpes simplex virus thymidine kinase geneQ45747423
Expression of a candidate ataxia-telangieetasia group D gene in cultured fibroblast cell lines and human tissuesQ47682236
Amplification of HER-2/neu and topoisomerase IIalpha in primary and metastatic breast cancer.Q49230662
Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.Q54069950
Intensified adjuvant therapy for pancreatic and periampullary adenocarcinoma: survival results and observations regarding patterns of failure, radiotherapy dose and CA19-9 levels.Q54085358
Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: a comparison with alpha-actinin.Q55034914
TGF-?-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator systemQ60609528
Balance of expression of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in chronic pancreatitisQ60609552
CD44 isoform expression in primary and metastatic pancreatic adenocarcinomaQ71690149
Induction of platelet‐derived growth factor A and B chains and over‐expression of their receptors in human pancreatic cancerQ72036047
Characterization of a transglutaminase expressed in human pancreatic adenocarcinoma cellsQ72655848
Duct epithelial cells cultured from human pancreas processed for transplantation retain differentiated ductal characteristicsQ73803440
Cytokeratins 7, 17, and 20 reactivity in pancreatic and ampulla of vater adenocarcinomas. Percentage of positivity and distribution is affected by the cut-point thresholdQ73858077
Expression of laminin-5-gamma-2 chain in intraductal papillary-mucinous and invasive ductal tumors of the pancreasQ73881726
Identifying markers for pancreatic cancer by gene expression analysisQ74263354
Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expressionQ77464625
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpancreatic cancerQ212961
P304page(s)1239-1249
P577publication date2002-04-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleDiscovery of novel tumor markers of pancreatic cancer using global gene expression technology
P478volume160

Reverse relations

cites work (P2860)
Q38723957"NextGen" Biologics: Bispecific Antibodies and Emerging Clinical Results
Q35304445A multistep high-content screening approach to identify novel functionally relevant target genes in pancreatic cancer
Q39554498A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis
Q33992146A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma
Q37497757Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma
Q39888180Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility
Q37263038Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors
Q38089806Applications of microarray technology to pancreatic cancer research and drug development
Q33531856Biobanking of human pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality.
Q28276398Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach
Q28834154Bioorthogonal labeling cell-surface proteins expressed in pancreatic cancer cells to identify potential diagnostic/therapeutic biomarkers
Q35017547CD109 Overexpression in Pancreatic Cancer Identified by Cell-Surface Glycoprotein Capture
Q31121505Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays
Q39842549Characterizing DNA methylation patterns in pancreatic cancer genome.
Q90262599Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells
Q42759235Claudin-1 required for HCV virus entry has high potential for phosphorylation and O-glycosylation
Q46915043Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer
Q35588895Comparison of the novel quantitative ARMS assay and an enriched PCR-ASO assay for K-ras mutations with conventional cytology on endobiliary brush cytology from 312 consecutive extrahepatic biliary stenoses
Q36344287Comprehensive Dissection of Transcriptome Data and Regulatory Factors in Pancreatic Cancer Cells.
Q42053166CpG island methylation profile of pancreatic intraepithelial neoplasia
Q40447853D-TMPP: a novel androgen-regulated gene preferentially expressed in prostate and prostate cancer that is the first characterized member of an eukaryotic gene family.
Q85995613Development of a cytokine-modified allogeneic whole cell pancreatic cancer vaccine
Q38311218Differential expression of insulin-like growth factor binding protein-5 in pancreatic adenocarcinomas: identification using DNA microarray
Q51488757Differentiation of multiple types of pancreatico-biliary tumors by molecular analysis of clinical specimens.
Q42721594Distinct pathways of pathogenesis of intraductal oncocytic papillary neoplasms and intraductal papillary mucinous neoplasms of the pancreas.
Q38945099Down regulated expression of Claudin-1 and Claudin-5 and up regulation of β-catenin: association with human glioma progression
Q35099833Down-regulation of nicotinamide N-methyltransferase induces apoptosis in human breast cancer cells via the mitochondria-mediated pathway
Q39690173Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines
Q24813318Evaluation of the similarity of gene expression data estimated with SAGE and Affymetrix GeneChips
Q28185685Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
Q53301032Expression of PSCA, PIWIL1 and TBX2 and its correlation with HPV16 infection in formalin-fixed, paraffin-embedded cervical squamous cell carcinoma specimens.
Q24337345Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer
Q81370836Expression of novel markers of pancreatic ductal adenocarcinoma in pancreatic nonductal neoplasms: additional evidence of different genetic pathways
Q37190226Expression profile and prognostic value of NNMT in patients with pancreatic cancer
Q33280569Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade
Q92826260Ferlin Overview: From Membrane to Cancer Biology
Q36899872Functional p38 MAPK identified by biomarker profiling of pancreatic cancer restrains growth through JNK inhibition and correlates with improved survival
Q35115628Gene Expression in Neoplasms of the Pancreas: Applications to Diagnostic Pathology
Q31156199Gene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinoma
Q94332166Gene expression profile after cardiopulmonary bypass and cardioplegic arrest
Q38294269Gene expression profiles in primary pancreatic tumors and metastatic lesions of Ela-c-myc transgenic mice
Q51599172Gene expression profiles of microdissected pancreatic ductal adenocarcinoma.
Q35094629Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas
Q30887318Gene expression profiling in islet biology and diabetes research
Q34928555Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays
Q36032931Gene overexpression in pancreatic adenocarcinoma: diagnostic and therapeutic implications
Q37772497Gene-expression profiling in pancreatic cancer
Q24798750Genetic alteration and gene expression modulation during cancer progression
Q34589293Genetics and pathology of pancreatic cancer
Q31041732Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection
Q35140486Genomics and the search for novel biomarkers in toxicology
Q42147260Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer
Q36944033High expression of TROP2 correlates with poor prognosis in pancreatic cancer.
Q40490949High-resolution genomic and expression profiling reveals 105 putative amplification target genes in pancreatic cancer
Q36326330Identification and characterization of the gene expression profiles for protein coding and non-coding RNAs of pancreatic ductal adenocarcinomas
Q40273975Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples
Q52789821Identification of candidate miRNA biomarkers for pancreatic ductal adenocarcinoma by weighted gene co-expression network analysis.
Q28238147Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling
Q35791572Identification of novel cellular targets in biliary tract cancers using global gene expression technology
Q24656609Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer
Q47433524Independent value of fascin immunoreactivity for predicting lymph node metastases in typical and atypical pulmonary carcinoids.
Q58689165Investigation of Archived Formalin-Fixed Paraffin-Embedded Pancreatic Tissue with Whole-Genome Gene Expression Microarray
Q35576601Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer
Q35627068Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma
Q28188395Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast
Q37620679Metabolism addiction in pancreatic cancer
Q34082610MicroRNA alterations of pancreatic intraepithelial neoplasias
Q35639853Microarray-based gene expression profiling in pancreatic ductal carcinoma: status quo and perspectives
Q38350940Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent
Q37614592Molecular changes in pancreatic cancer
Q57422493Molecular diagnostics in pancreatic cancer
Q36485336Molecular genetics of pancreatic ductal adenocarcinomas and recent implications for translational efforts
Q36829524Molecular genetics of pancreatic intraepithelial neoplasia
Q53359744Molecular imaging of prostate cancer.
Q37081461Molecular markers of pancreatic cancer: development and clinical relevance
Q47620397Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray
Q41096139NMDA receptors are important regulators of pancreatic cancer and are potential targets for treatment
Q30489770New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.
Q90216387Nicotinamide N‑methyltransferase induces the proliferation and invasion of squamous cell carcinoma cells
Q73614651Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
Q33391858Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.
Q54422958Novel blood biomarkers of pancreatic cancer-associated diabetes mellitus identified by peripheral blood-based gene expression profiles.
Q26825644Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
Q99567378N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells
Q36124027Osteopontin expression is associated with improved survival in patients with pancreatic adenocarcinoma
Q30797702Overexpressed Claudin-1 Can Be Visualized Endoscopically in Colonic Adenomas In Vivo
Q33234488Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma
Q35032539Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer
Q36308123Overexpression of annexin 1 in pancreatic cancer and its clinical significance
Q38774676Overexpression of trophoblast cell surface antigen 2 as an independent marker for a poor prognosis and as a potential therapeutic target in epithelial ovarian carcinoma
Q92715653Overexpression of trophoblast cell surface antigen 2 is associated with BRAF V600E mutation and aggressive behavior in papillary thyroid cancer
Q37104978PSCA and Oct-4 expression in the benign and malignant lesions of gallbladder: implication for carcinogenesis, progression, and prognosis of gallbladder adenocarcinoma
Q30483618Pancreatic Expression database: a generic model for the organization, integration and mining of complex cancer datasets
Q39870304Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma.
Q24170403Pancreatic cancer
Q35013204Pancreatic cancer biology and genetics
Q38354856Pancreatic cancer: diagnosis and treatments
Q37125627Pancreatic carcinogenesis
Q34526464Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortality
Q41859957Poly(A) RT-PCR measurement of diagnostic genes in pancreatic juice in pancreatic cancer
Q54391141Prognostic roles of human equilibrative transporter 1 (hENT-1) and ribonucleoside reductase subunit M1 (RRM1) in resected pancreatic cancer.
Q37448935Prognostic signature for pancreatic cancer: are we close?
Q37186552Prostate stem cell antigen: a prospective therapeutic and diagnostic target
Q40295403Proteomic analysis of primary cell lines identifies protein changes present in renal cell carcinoma
Q36026306Proteomic profiling of pancreatic cancer for biomarker discovery
Q53620234Quantitative proteomic profiling of pancreatic cancer juice.
Q30534663Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs).
Q58714472Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem
Q36297522Role of adjuvant therapy in the management of pancreatic cancer
Q35170428Role of tissue stroma in cancer cell invasion
Q47806512Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma
Q51799739Serum levels of nicotinamide N-methyltransferase in patients with lung cancer.
Q40070727Stat3 up-regulates expression of nicotinamide N-methyltransferase in human cancer cells
Q33862088Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer
Q36685675Target discovery and validation in pancreatic cancer
Q35062469The OSBP-related proteins: a novel protein family involved in vesicle transport, cellular lipid metabolism, and cell signalling.
Q47866664The Role of Drebrin in Cancer Cell Invasion
Q37302556The claudin family of proteins in human malignancy: a clinical perspective
Q40603608The efficacy of tyrosine kinase inhibitors on human pancreatic cancer cell lines
Q37817143The pancreatic cancer proteome - recent advances and future promise
Q36542828The role of epigenetic alterations in pancreatic cancer
Q34476583Trop-2 protein overexpression is an independent marker for predicting disease recurrence in endometrioid endometrial carcinoma
Q38957238Universal antibody conjugation to nanoparticles using the Fcγ receptor I (FcγRI): quantitative profiling of membrane biomarkers

Search more.