Target discovery and validation in pancreatic cancer

scientific article published on January 2007

Target discovery and validation in pancreatic cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1385/1-59745-165-7:57
P932PMC publication ID2662995
P698PubMed publication ID17172725
P5875ResearchGate publication ID6626821

P50authorAnirban MaitraQ63019787
Jonathan R. PollackQ73921770
P2093author name stringMads Gronborg
Robert M Beaty
P2860cites workPancreatic cancerQ24170403
NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteinsQ24558592
Cluster analysis and display of genome-wide expression patternsQ24644463
MicroSAGE: a modified procedure for serial analysis of gene expression in limited amounts of tissue.Q39727385
Comprehensive transcript analysis in small quantities of mRNA by SAGE-liteQ39729762
Epithelial tight junction proteins as potential antibody targets for pancarcinoma therapy.Q40449793
Claudin-4: a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin.Q40783616
Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250.Q45012593
Pancreatic intraepithelial neoplasiaQ47636868
Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma.Q47985761
Claudin 4 protein expression in primary and metastatic pancreatic cancer: support for use as a therapeutic target.Q51019711
Comprehensive Proteomic Analysis of Human Pancreatic JuiceQ57979970
Microcolumns with self-assembled particle frits for proteomicsQ58447080
Improvement and simplification of low-background silver staining of proteins by using sodium dithioniteQ69057110
Immunohistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasmsQ71048246
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomasQ73555144
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesisQ73614651
Serial analysis of gene expressionQ27860777
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Large-scale analysis of the yeast proteome by multidimensional protein identification technologyQ28131778
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarraysQ28185685
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumoursQ28206040
An automated multidimensional protein identification technology for shotgun proteomicsQ28214478
Mesothelin: a new target for immunotherapyQ28268571
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinomaQ28300339
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1Q29616726
Use of a cDNA microarray to analyse gene expression patterns in human cancerQ29618814
Pancreatic cancerQ29622871
SAGEmap: a public gene expression resourceQ30651577
The Stanford Microarray Database: data access and quality assessment toolsQ30760675
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).Q30781823
A public database for gene expression in human cancersQ30809646
Identification of hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein I as a biomarker for pancreatic ductal adenocarcinoma by protein biochip technologyQ30827839
Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma.Q30991221
Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.Q31034362
Relationships and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression.Q31037582
Discovery of novel tumor markers of pancreatic cancer using global gene expression technologyQ31048088
Substantially enhanced cloning efficiency of SAGE (Serial Analysis of Gene Expression) by adding a heating step to the original protocolQ31933958
Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma: final results of a GERCOR multicenter phase II studyQ33341477
Proteomics to study genes and genomesQ33906818
Gene discovery using the serial analysis of gene expression technique: implications for cancer researchQ34270355
Molecular pathology of pancreatic cancerQ34372454
A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridizationQ34396036
A highly sensitive silver stain for detecting proteins and peptides in polyacrylamide gelsQ34454905
Early detection of pancreatic carcinomaQ34684186
An introduction to pancreatic adenocarcinoma genetics, pathology and therapy.Q35087212
BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implicationsQ35810230
Serial analysis of gene expression (SAGE): unraveling the bioinformatics toolsQ35845621
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patientsQ36399737
Amplified RNA synthesized from limited quantities of heterogeneous cDNA.Q37705357
Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocolsQ39543462
P407language of work or nameEnglishQ1860
P921main subjectpancreatic cancerQ212961
P304page(s)57-89
P577publication date2007-01-01
P1433published inMethods in Molecular BiologyQ15752859
P1476titleTarget discovery and validation in pancreatic cancer
P478volume360

Reverse relations

Q30409158Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivitycites workP2860

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