Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion

scientific article published on January 2002

Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1515/BC.2002.016
P698PubMed publication ID11928810

P50authorChristophe StoveQ40479091
Marc BrackeQ55232071
P2093author name stringMarc Goethals
Joël Vandekerckhove
Erik Bruyneel
Marc Mareel
Filip Ryniers
Liesbeth Brackenier
Veerle Noë
P2860cites workActivation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasionQ28142815
Induction of tyrosine phosphorylation and association of beta-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluenceQ28244489
The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasisQ34165118
The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrowQ34223998
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherinQ34290465
Role of myofibroblasts at the invasion frontQ34584808
Soluble E-cadherin fragments increased in circulation of cancer patientsQ35978360
Characterization of soluble E-cadherin as a disease marker in gastric cancer patientsQ36115556
Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasionQ36115941
Cell adhesion molecules in bladder cancer: soluble serum E-cadherin correlates with predictors of recurrenceQ36135912
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC geneQ36232389
An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signalingQ36237334
In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell deathQ36382475
Soluble forms of the adhesion molecule E-cadherin in urineQ39642989
Oncogenic activation of tyrosine kinasesQ40757534
Cleavage and shedding of E-cadherin after induction of apoptosisQ40842886
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumorsQ40949632
Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive propertiesQ41126999
TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragmentQ41233767
Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA).Q41260093
Cadherin-dependent cell aggregation is affected by decapeptide derived from rat extracellular super-oxide dismutase.Q41349178
The urokinase-type plasminogen activator system in cancer metastasis: A reviewQ41522331
E-cadherin/catenin/cytoskeleton complex: a regulator of cancer invasionQ41640504
ECM and cell surface proteolysis: regulating cellular ecologyQ41656253
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient miceQ45754755
Purification and characterization of NCAD90, a soluble endogenous form of N-cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function.Q52223290
P433issue1
P304page(s)159-165
P577publication date2002-01-01
P1433published inBiological ChemistryQ4914948
P1476titlePlasmin produces an E-cadherin fragment that stimulates cancer cell invasion
P478volume383

Reverse relations

cites work (P2860)
Q33878896ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.
Q80503595ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis
Q44366812Altered gene expression in mouse livers after dichloroacetic acid exposure
Q36615956Assessment of a fragment of e-cadherin as a serum biomarker with predictive value for prostate cancer.
Q38679713Beyond a tumor suppressor: Soluble E-cadherin promotes the progression of cancer.
Q24629108Cancer Cells Cut Homophilic Cell Adhesion Molecules and Run
Q42734789Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA.
Q37428089Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis
Q101124627Curcumin Inhibits the Migration and Invasion of Non-Small-Cell Lung Cancer Cells Through Radiation-Induced Suppression of Epithelial-Mesenchymal Transition and Soluble E-Cadherin Expression
Q31134141DC-CLM, a cadherin-like molecule cloned from human dendritic cells, inhibits growth of breast cancer cells
Q40796445Differential downregulation of e-cadherin and desmoglein by epidermal growth factor.
Q34471105Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
Q26865483E-cadherin's dark side: possible role in tumor progression
Q39453489EGF promotes the shedding of soluble E-cadherin in an ADAM10-dependent manner in prostate epithelial cells.
Q40511545Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3.
Q35884866Epithelial-mesenchymal transition in oral squamous cell carcinoma
Q41430438Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism
Q39104038Exploiting the Gastric Epithelial Barrier: Helicobacter pylori's Attack on Tight and Adherens Junctions
Q35017040Fate of E-cadherin in early RPE cultures: transient accumulation of truncated peptides at nonjunctional sites
Q30319058Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10.
Q85166357Increased Levels of Soluble Vascular Endothelial Cadherin are Associated with Poor Outcome in Severe Sepsis
Q28292665Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin
Q40036786Lysophosphatidic acid (LPA) promotes E-cadherin ectodomain shedding and OVCA429 cell invasion in an uPA-dependent manner
Q33906860MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis
Q37565430MT2-MMP induces proteolysis and leads to EMT in carcinomas
Q48312486Mangiferin blocks proliferation and induces apoptosis of breast cancer cells via suppression of the mevalonate pathway and by proteasome inhibition
Q90665051MicroRNA-200 family governs ovarian inclusion cyst formation and mode of ovarian cancer spread
Q40074094Nuclear E-cadherin and VHL immunoreactivity are prognostic indicators of clear-cell renal cell carcinoma
Q40715721Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes
Q34584808Role of myofibroblasts at the invasion front
Q35170428Role of tissue stroma in cancer cell invasion
Q34279705Soluble E-cadherin: more than a symptom of disease.
Q40222376Soluble N-cadherin fragment promotes angiogenesis
Q36977717Soluble cadherins as cancer biomarkers
Q36326605Targeting Cathepsin B for Cancer Therapies
Q30362587Use of silicon chip technology to detect protein-based tumor markers in bladder cancer

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