Angiostatin effects on endothelial cells mediated by ceramide and RhoA.

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Angiostatin effects on endothelial cells mediated by ceramide and RhoA. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/EMBO-REPORTS/KVE115
P932PMC publication ID1083909
P698PubMed publication ID11415988
P5875ResearchGate publication ID11924232

P2093author name stringBeckett MA
Gupta N
Khodarev NN
Khorasani L
Kufe DW
Nodzenski E
Weichselbaum RR
Yu J
P2860cites workAngiostatin binds ATP synthase on the surface of human endothelial cellsQ22009028
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signalingQ22009049
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinaseQ22010473
Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinaseQ24290361
Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formationQ24290939
Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape changeQ24313072
Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2Q24670491
Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motilityQ24682432
Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinaseQ28646403
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinomaQ29615947
Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD.Q30454412
Ceramide mediates radiation-induced death of endothelium.Q33916405
C3 toxin activates the stress signaling pathways, JNK and p38, but antagonizes the activation of AP-1 in rat-1 cellsQ38328989
Growth factor signal transduction immediately after two-thirds partial hepatectomy in the rat.Q38500706
Rho and Rab small G proteins coordinately reorganize stress fibers and focal adhesions in MDCK cellsQ38613114
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motilityQ39714519
rho gene products, botulinum C3 exoenzyme and cell adhesionQ40886136
Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrateQ41035564
Regulation of the RhoA pathway in human endothelial cell spreading on type IV collagen: role of calcium influxQ42478138
RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.Q42799714
Clostridium botulinum C3 exoenzyme stimulates GLUT4-mediated glucose transport, but not glycogen synthesis, in 3T3-L1 adipocytes--a potential role of rho?Q42806179
Alterations of blood vessel development by endothelial cells overexpressing fibroblast growth factor-2.Q42806710
Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen speciesQ43506772
Involvement of de novo ceramide biosynthesis in tumor necrosis factor-alpha/cycloheximide-induced cerebral endothelial cell deathQ47954345
Regulation of astrocyte morphology by RhoA and lysophosphatidic acidQ48329978
Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinaseQ71148377
Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumorsQ73121301
Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiencyQ73430532
Angiogenic balance in human melanoma: expression of VEGF, bFGF, IL-8, PDGF and angiostatin in relation to vascular density of xenografts in vivoQ73863756
Cytoskeletal disruption accelerates caspase-3 activation and alters the intracellular membrane reorganization in DNA damage-induced apoptosisQ74172291
Angiostatin induces mitotic cell death of proliferating endothelial cellsQ74241398
Endostatin induces endothelial cell apoptosisQ77335987
Rho A regulates sustained smooth muscle contraction through cytoskeletal reorganization of HSP27Q77649580
Multiple forms of angiostatin induce apoptosis in endothelial cellsQ77655144
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
ceramidesQ424213
P304page(s)536-540
P577publication date2001-06-01
P1433published inEMBO ReportsQ5323356
P1476titleAngiostatin effects on endothelial cells mediated by ceramide and RhoA.
P478volume2

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cites work (P2860)
Q35747758Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells
Q24310005Angiomotin regulates endothelial cell-cell junctions and cell motility
Q31123431Angiostatin up-regulation in gastric cancer cell SGC7901 inhibits tumorigenesis in nude mice
Q48289937Brain microvessel endothelin type A receptors are coupled to ceramide production
Q42285769Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism
Q44760028Dose-dependent response of tumor vasculature to radiation therapy in combination with Sunitinib depicted by three-dimensional high-frequency power Doppler ultrasound
Q33237979EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV.
Q45096402Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium
Q44203329Identification of the LIM kinase-1 as a ceramide-regulated gene in renal mesangial cells
Q33510915Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression
Q35983863Involvement of ceramide in cell death responses in the pulmonary circulation
Q37727048Measles virus-induced immunosuppression: from effectors to mechanisms
Q35151099Mechanism and its regulation of tumor-induced angiogenesis
Q37375507Membrane signaling induced by high doses of ionizing radiation in the endothelial compartment. Relevance in radiation toxicity
Q45831726Plasma levels of angiostatin and endostatin remain unchanged for the first 3 weeks after colorectal cancer surgery
Q88532146RACking up ceramide-induced islet β-cell dysfunction
Q38418407The role of sphingolipids in endothelial barrier function.
Q38008461Vascular strategies for enhancing tumour response to radiation therapy

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