Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus

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Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus is …
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scholarly articleQ13442814

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P356DOI10.1016/S0960-894X(99)00235-8
P698PubMed publication ID10386942

P2093author name stringC Mao
T K Venkatachalam
F M Uckun
E A Sudbeck
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Structure-based design of N-[2-(1-piperidinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptaseQ42537167
5-Alkyl-2-[(methylthiomethyl)thio]-6-(benzyl)-pyrimidin-4-(1H)-ones as potent non-nucleoside reverse transcriptase inhibitors of S-DABO seriesQ42537190
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LUDI: rule-based automatic design of new substituents for enzyme inhibitor leadsQ44114180
Scintillation proximity assayQ59062768
Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reserve transcriptaseQ77634517
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1593-8
P577publication date1999-06-07
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleRational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus
P478volume9

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