A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea]).

scientific article published on February 2012

A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea]). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1517/13543784.2012.655422
P698PubMed publication ID22292483

P50authorFatih M. UckunQ89542817
Sanjive QaziQ129085860
P2093author name stringOsmond J D'Cruz
Seang Yiv
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A study of the potential of the pig as a model for the vaginal irritancy of benzalkonium chloride in comparison to the nonirritant microbicide PHI-443 and the spermicide vanadocene dithiocarbamateQ46612809
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Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. COL-1492 Phase II Study GroupQ39547647
Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781.Q39634548
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Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogsQ42553182
Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel.Q43007169
Carraguard Vaginal Gel Safety in HIV-Positive Women and Men in South AfricaQ44811371
Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptivesQ44884891
A randomized Phase I vaginal safety study of three concentrations of C31G vs. Extra Strength Gynol II.Q44904458
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P433issue3
P407language of work or nameEnglishQ1860
P304page(s)265-279
P577publication date2012-02-01
P1433published inExpert Opinion on Investigational DrugsQ5421208
P1476titleA novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea]).
P478volume21

Reverse relations

cites work (P2860)
Q35163175Application of Design of Experiment and Simulation Methods to Liquid Chromatography Analysis of Topical HIV Microbicides Stampidine and HI443.
Q58692742Disubstituted 4-Chloro-3-nitrophenylthiourea Derivatives: Antimicrobial and Cytotoxic Studies
Q40231384New thiourea and 1,3-thiazolidin-4-one derivatives effective on the HIV-1 virus
Q38186138Vaginal microbicides and their delivery platforms

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