review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1048795058 |
P356 | DOI | 10.1038/35008000 |
P3181 | OpenCitations bibliographic resource ID | 273949 |
P698 | PubMed publication ID | 10783877 |
P5875 | ResearchGate publication ID | 12532653 |
P50 | author | Norbert Perrimon | Q38523404 |
P2093 | author name string | M Bernfield | |
P2860 | cites work | Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome | Q24320198 |
The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate | Q24323532 | ||
Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated? | Q24561731 | ||
Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans | Q28213234 | ||
Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2 | Q28273441 | ||
Regulated diversity of heparan sulfate | Q28282444 | ||
The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate | Q28284035 | ||
Matrix proteoglycans: from molecular design to cellular function | Q28284300 | ||
The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes | Q28288396 | ||
Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme | Q28586968 | ||
??? | Q22009535 | ||
Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase | Q28589603 | ||
Heparin is essential for the storage of specific granule proteases in mast cells | Q28589787 | ||
Comparative genomics of the eukaryotes | Q29547504 | ||
Functions of cell surface heparan sulfate proteoglycans | Q29618521 | ||
The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila | Q33869131 | ||
Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity | Q34481268 | ||
OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner. | Q36255453 | ||
Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase | Q36316404 | ||
Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation. | Q42439019 | ||
Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing | Q46769553 | ||
Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling | Q47070638 | ||
Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo | Q47070848 | ||
Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan | Q47071002 | ||
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion | Q47072416 | ||
Syndecans, heparan sulfate proteoglycans, maintain the proteolytic balance of acute wound fluids. | Q52186911 | ||
Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan | Q52225676 | ||
Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion | Q64146688 | ||
Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice | Q73977149 | ||
P433 | issue | 6779 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 725-8 | |
P577 | publication date | 2000-04-13 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Specificities of heparan sulphate proteoglycans in developmental processes | |
P478 | volume | 404 |
Q48773643 | 'Heparin'--from anticoagulant drug into the new biology |
Q27650294 | 2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis |
Q28188262 | A 4-Mb BAC/PAC contig and complete genomic structure of the GPC5/GPC6 gene cluster on chromosome 13q32 |
Q27490518 | A Turn-like Structure "KKPE" Segment Mediates the Specific Binding of Viral Protein A27 to Heparin and Heparan Sulfate on Cell Surfaces |
Q38972454 | A combinatorial approach to biophysically characterise chemokine-glycan binding affinities for drug development |
Q30800594 | A focused microarray approach to functional glycomics: transcriptional regulation of the glycome |
Q28943481 | A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis |
Q28253785 | A heparan sulfate-facilitated and raft-dependent macropinocytosis of eosinophil cationic protein |
Q99716350 | A multi-layered and dynamic apical extracellular matrix shapes the vulva lumen in Caenorhabditis elegans |
Q44816865 | A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase. |
Q41442587 | A new sequencing approach for N-unsubstituted heparin/heparan sulfate oligosaccharides |
Q33492749 | A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells |
Q24291238 | A novel human Gal-3-O-sulfotransferase: molecular cloning, characterization, and its implications in biosynthesis of (SO(4)-3)Galbeta1-4(Fucalpha1-3)GlcNAc |
Q40504156 | A novel strategy for defining critical amino acid residues involved in protein/glycosaminoglycan interactions |
Q34096196 | A quantitative structure-activity relationship (QSAR) study on glycan array data to determine the specificities of glycan-binding proteins |
Q41895425 | A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor |
Q35219603 | A starting place for the road to function |
Q46594680 | A unique role for 6-O sulfation modification in zebrafish vascular development |
Q33951903 | Akt/PKB regulates laminin and collagen IV isotypes of the basement membrane |
Q28587283 | Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification |
Q30488977 | Altered heparan sulfate structure in mice with deleted NDST3 gene function. |
Q38338415 | Analysis of Glycosaminoglycans Using Mass Spectrometry |
Q90260004 | Analysis of Heparan sulfate/heparin from Colla corii asini by liquid chromatography-electrospray ion trap mass spectrometry |
Q47073784 | Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry. |
Q37225793 | Apoptosis regulates notochord development in Xenopus |
Q28215514 | Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy |
Q28237570 | Autocrine/paracrine secreted Frizzled-related protein 2 induces cellular resistance to apoptosis: a possible mechanism of mammary tumorigenesis |
Q35551123 | Axis of evil: molecular mechanisms of cancer metastasis |
Q34152297 | BMP signaling is required locally to pattern the dorsal telencephalic midline |
Q52902554 | Benzylidene Acetal Protecting Group as Carboxylic Acid Surrogate: Synthesis of Functionalized Uronic Acids and Sugar Amino Acids. |
Q24529120 | Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway |
Q38936714 | Biological roles of glycans |
Q34594698 | Biosynthesis of chondroitin and heparan sulfate in chinese hamster ovary cells depends on xylosyltransferase II. |
Q24535653 | Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties |
Q24291240 | Bipartite interaction between neurofibromatosis type I protein (neurofibromin) and syndecan transmembrane heparan sulfate proteoglycans |
Q46905196 | Brain heparanase expression is up-regulated during postnatal development and hypoxia-induced neovascularization in adult rats |
Q36635814 | Building from the Ground up: Basement Membranes in Drosophila Development |
Q24544140 | CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells |
Q44450082 | Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis |
Q45085052 | Caprine mucopolysaccharidosis IIID: fetal and neonatal brain and liver glycosaminoglycan and morphological perturbations |
Q27660652 | Catalytic Mechanism of Heparinase II Investigated by Site-directed Mutagenesis and the Crystal Structure with Its Substrate |
Q39657115 | Cell behavior on extracellular matrix mimic materials based on mussel adhesive protein fused with functional peptides |
Q42775907 | Cell surface glycoconjugate abnormalities and corneal epithelial wound healing in the pax6+/- mouse model of aniridia-related keratopathy |
Q34464575 | Cell surface heparan sulfate and its roles in assisting viral infections |
Q34873899 | Cell surface proteins Nasrat and Polehole stabilize the Torso-like extracellular determinant in Drosophila oogenesis |
Q37716635 | Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells |
Q38363614 | Cell-surface prion protein interacts with glycosaminoglycans |
Q28592534 | Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function |
Q54656265 | Cervical dysplasia: assessing methylation status (Methylight) of CCNA1, DAPK1, HS3ST2, PAX1 and TFPI2 to improve diagnostic accuracy. |
Q38931511 | Characterization and mechanisms of photoageing-related changes in skin. Damages of basement membrane and dermal structures |
Q41755909 | Characterization of METH-1/ADAMTS1 processing reveals two distinct active forms |
Q40993911 | Characterization of Ovine Dermal Papilla Cell Aggregation |
Q38308225 | Characterization of heparin-protein interaction by saturation transfer difference (STD) NMR. |
Q38306497 | Characterization of the stromal cell-derived factor-1alpha-heparin complex |
Q37371753 | Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals |
Q24685603 | Chondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I |
Q38308566 | Chondroitin 4-O-sulfotransferase-1 regulates E disaccharide expression of chondroitin sulfate required for herpes simplex virus infectivity |
Q28586264 | Chondroitin 4-O-sulfotransferase-1 regulates the chain length of chondroitin sulfate in co-operation with chondroitin N-acetylgalactosaminyltransferase-2 |
Q96952170 | Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1 |
Q44450085 | Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans |
Q50569319 | Chondroitin sulfate effects on neural stem cell differentiation. |
Q28588352 | Chondroitin sulfate synthase-2 is necessary for chain extension of chondroitin sulfate but not critical for skeletal development |
Q34232172 | Chondroitin sulfate synthase-2/chondroitin polymerizing factor has two variants with distinct function. |
Q30747604 | Chondroitin sulfate/dermatan sulfate hybrid chains from embryonic pig brain, which contain a higher proportion of L-iduronic acid than those from adult pig brain, exhibit neuritogenic and growth factor binding activities |
Q39094473 | Chondroitin sulfates and their binding molecules in the central nervous system |
Q35881486 | Cleavage of PGRP-LC receptor in the Drosophila IMD pathway in response to live bacterial infection in S2 cells |
Q33188043 | Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration |
Q35154990 | Community-based network study of protein-carbohydrate interactions in plant lectins using glycan array data |
Q33584274 | Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features |
Q39518015 | Computational analysis of interactions in structurally available protein-glycosaminoglycan complexes |
Q39178586 | Computational drill down on FGF1-heparin interactions through methodological evaluation |
Q47071823 | Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity |
Q36980418 | Control of cell fate decisions |
Q24564054 | Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A |
Q27640414 | Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis |
Q34505592 | Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product |
Q24534902 | Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling |
Q24816968 | D-glucuronyl C5-epimerase acts in dorso-ventral axis formation in zebrafish |
Q35697330 | Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin. |
Q34113087 | Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation |
Q28273746 | Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32) |
Q42975266 | Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation |
Q79260067 | Determining Heparan Sulfate Structure in the Vicinity of Specific Sulfotransferase Recognition Sites by Mass Spectrometry |
Q35068997 | Development and maintenance of neuronal architecture at the ventral midline of C. elegans. |
Q52134689 | Developmental biology. Fishing for morphogens. |
Q35219661 | Developmental roles of heparan sulfate proteoglycans in Drosophila |
Q38325965 | Differential Characterization and Classification of Tissue Specific Glycosaminoglycans by Tandem Mass Spectrometry and Statistical Methods. |
Q45119849 | Differential expression of heparan sulfate 6-O-sulfotransferase isoforms in the mouse embryo suggests distinctive roles during organogenesis |
Q28394538 | Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells |
Q48202252 | Differential sulfations and epimerization define heparan sulfate specificity in nervous system development |
Q37379770 | Differentiation of 3-O-sulfated heparin disaccharide isomers: identification of structural aspects of the heparin CCL2 binding motif |
Q73339920 | Direct isolation and sequencing of specific protein-binding glycosaminoglycans |
Q45261009 | Distinct substrate specificities of bacterial heparinases against N-unsubstituted glucosamine residues in heparan sulfate |
Q34970023 | Distribution of syndecan-1 protein in developing mouse teeth |
Q28577838 | Diurnal pineal 3-O-sulphotransferase 2 expression controlled by beta-adrenergic repression |
Q38101685 | Does mammographic density reflect the expression of breast cancer markers? |
Q34279840 | Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist Noggin |
Q56395838 | Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase |
Q48360653 | Drosophila perlecan modulates FGF and hedgehog signals to activate neural stem cell division |
Q43726761 | Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events |
Q52137443 | Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan gene. |
Q44301511 | EXT gene family member rib-2 is essential for embryonic development and heparan sulfate biosynthesis in Caenorhabditis elegans |
Q37875379 | Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives |
Q35281711 | Effects of culture on PAMPS/PDMAAm double-network gel on chondrogenic differentiation of mouse C3H10T1/2 cells: in vitro experimental study |
Q73176598 | Effects of platelet factor 4 on expression of bone marrow heparan sulfate in syngenic bone marrow transplantation mice |
Q36095569 | Efficient and stereocontrolled synthesis of chondroitin mono- and disaccharide linked to variously sulfated biotinylated trisaccharides of the linkage region of proteoglycans. |
Q44367072 | Efficient selective preparation of methyl-1,2,4-tri-O-acetyl-3-O-benzyl-beta-L-idopyranuronate from methyl 3-O-benzyl-L-iduronate |
Q35801306 | Elastin-based biomaterials and mesenchymal stem cells |
Q42724030 | Embryo emergent: elucidating the cell biology of development. The Santa Cruz Conference on Developmental Biology 2000. |
Q39431959 | Endocan in cancers: a lesson from a circulating dermatan sulfate proteoglycan |
Q24291764 | Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity |
Q35967045 | Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall |
Q44660320 | Enzymatic Synthesis of Chondroitin and Its Derivatives Catalyzed by Hyaluronidase |
Q52100047 | Essential role of glycosaminoglycans in Fgf signaling during mouse gastrulation. |
Q42378449 | Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells |
Q27015054 | Exploring mechanisms of FGF signalling through the lens of structural biology |
Q48494708 | Expression analysis of Sulf1 in the chick forebrain at early and late stages of development |
Q52135220 | Expression and localization of proteoglycans during limb myogenic activation. |
Q33325701 | Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas |
Q26851937 | Extracellular distribution of diffusible growth factors controlled by heparan sulfate proteoglycans during mammalian embryogenesis |
Q34633398 | Extracellular matrix-modulated Heartless signaling in Drosophila blood progenitors regulates their differentiation via a Ras/ETS/FOG pathway and target of rapamycin function. |
Q33946703 | Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body |
Q36083438 | Fibroblast growth factor signaling and the function and assembly of basement membranes |
Q28142123 | Fibroblast growth factor-binding protein is a novel partner for perlecan protein core |
Q35129459 | Formation of the long range Dpp morphogen gradient |
Q28143123 | Fringe is a glycosyltransferase that modifies Notch |
Q28469504 | Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans |
Q42154353 | Functional abnormalities of heparan sulfate in mucopolysaccharidosis-I are associated with defective biologic activity of FGF-2 on human multipotent progenitor cells |
Q46828499 | Functional analysis of proteoglycan galactosyltransferase II RNA interference mutant flies. |
Q28510831 | Functional analysis of the chondroitin 6-sulfotransferase gene in relation to lymphocyte subpopulations, brain development, and oversulfated chondroitin sulfates |
Q26865592 | Functional aspects of the interaction between interleukin-8 and sulfated glycosaminoglycans |
Q34026281 | Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila |
Q52681142 | Functional conservation of the human EXT1 tumor suppressor gene and its Drosophila homolog tout velu. |
Q36448809 | Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females. |
Q35138095 | Galactosyltransferase--still up and running |
Q33811652 | Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coli |
Q44366919 | Gene expression of EXT1 and EXT2 during mouse brain development |
Q52727531 | Glycobiology of syndecan-1 in bacterial infections. |
Q37002911 | Glycoform quantification of chondroitin/dermatan sulfate using a liquid chromatography-tandem mass spectrometry platform |
Q34205805 | Glycohistochemistry: the why and how of detection and localization of endogenous lectins. |
Q35906116 | Glycomics: a pathway to a class of new and improved therapeutics |
Q33391706 | Glycosaminoglycan (GAG) Biosynthesis and GAG-Binding Proteins |
Q26823079 | Glycosaminoglycan glycomics using mass spectrometry |
Q34982927 | Glycosaminoglycans modulate RANKL-induced osteoclastogenesis |
Q37012083 | Glypican-1 as a Biomarker for Prostate Cancer: Isolation and Characterization |
Q37351931 | Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis |
Q52714362 | Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden. |
Q36124126 | Glypican-3 and alphafetoprotein as diagnostic tests for hepatocellular carcinoma |
Q40609659 | Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells |
Q73638685 | Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma |
Q28285447 | Glypican-3: from the mutations of Simpson-Golabi-Behmel genetic syndrome to a tumor marker for hepatocellular carcinoma |
Q30874185 | Glypicans. |
Q35234613 | Golgi during development |
Q36321055 | Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells |
Q28609767 | HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient |
Q37095486 | Harnessing glycomics technologies: integrating structure with function for glycan characterization |
Q34366233 | Heads or tails: Wnts and anterior-posterior patterning |
Q33817351 | Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans. |
Q47917119 | Heparan Sulfate Proteoglycans Mediate the Invasion of Cardiomyocytes by Trypanosoma cruzi |
Q42363800 | Heparan Sulfate: A Potential Candidate for the Development of Biomimetic Immunomodulatory Membranes |
Q35219652 | Heparan sulfate 2-O-sulfotransferase (Hs2st) and mouse development. |
Q43215860 | Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin |
Q44463036 | Heparan sulfate 6-o-sulfotransferase is essential for muscle development in zebrafish. |
Q38306324 | Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development |
Q30433400 | Heparan sulfate acts as a bone morphogenetic protein coreceptor by facilitating ligand-induced receptor hetero-oligomerization |
Q34989516 | Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes |
Q34174472 | Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase |
Q35531571 | Heparan sulfate differences in rheumatoid arthritis versus healthy sera |
Q34989559 | Heparan sulfate fine structure and specificity of proteoglycan functions |
Q73881083 | Heparan sulfate glycosaminoglycan expression in the intestinal tract and ovary of fully engorged adult females of the cattle tick Boophilus microplus and in their laid eggs |
Q47070189 | Heparan sulfate polymerization in Drosophila |
Q34413225 | Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation. |
Q34029158 | Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1. |
Q28344801 | Heparan sulfate proteoglycans as regulators of fibroblast growth factor-2 receptor binding in breast carcinomas |
Q28204970 | Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients |
Q34328750 | Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena |
Q34310368 | Heparan sulfate proteoglycans: intricate molecules with intriguing functions. |
Q51889188 | Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. |
Q44462178 | Heparan sulfate-FGF10 interactions during lung morphogenesis |
Q40530698 | Heparan sulfate-independent infection attenuates high-neurovirulence GDVII virus-induced encephalitis |
Q38134808 | Heparan sulfate-protein binding specificity |
Q31882323 | Heparan sulfate: decoding a dynamic multifunctional cell regulator |
Q34328757 | Heparan sulfate: growth control with a restricted sequence menu |
Q30689506 | Heparan sulfate: lessons from knockout mice |
Q28180966 | Heparan sulfates expressed in the distal lung are required for Fgf10 binding to the epithelium and for airway branching |
Q37119533 | Heparan sulphate biosynthesis and disease |
Q40661301 | Heparan sulphate glycosaminoglycans derived from endothelial cells and smooth muscle cells differentially modulate fibroblast growth factor-2 biological activity through fibroblast growth factor receptor-1. |
Q27626606 | Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I |
Q41504553 | Heparanase Inhibitors Facilitate the Assembly of the Basement Membrane in Artificial Skin |
Q24303785 | Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin |
Q33927046 | Heparin and heparan sulfate: biosynthesis, structure and function |
Q38352991 | Heterogeneity of the chondroitin sulfate portion of phosphacan/6B4 proteoglycan regulates its binding affinity for pleiotrophin/heparin binding growth-associated molecule. |
Q26995332 | Human genetic disorders and knockout mice deficient in glycosaminoglycan |
Q24533427 | Human glycosaminoglycan glucuronyltransferase I gene and a related processed pseudogene: genomic structure, chromosomal mapping and characterization |
Q24631229 | Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis |
Q38358997 | Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans. Two novel homologs exhibit broad specificity toward |
Q28566524 | Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage |
Q35077801 | Identification of amino acid residues important for heparan sulfate proteoglycan interaction within variable region 3 of the feline immunodeficiency virus surface glycoprotein |
Q50335972 | Identification of chondroitin sulfate glucuronyltransferase as chondroitin synthase-3 involved in chondroitin polymerization: chondroitin polymerization is achieved by multiple enzyme complexes consisting of chondroitin synthase family members |
Q37462495 | Impact of Sulfatase-2 on cancer progression and prognosis in patients with renal cell carcinoma |
Q57242318 | Improved de novo sequencing of heparin/heparan sulfate oligosaccharides by propionylation of sites of sulfation |
Q42931605 | Improved workup for glycosaminoglycan disaccharide analysis using CE with LIF detection |
Q44542416 | In vitro heparan sulfate polymerization: crucial roles of core protein moieties of primer substrates in addition to the EXT1-EXT2 interaction |
Q24314370 | In vitro polymerization of heparan sulfate backbone by the EXT proteins |
Q40205392 | In vivo and in vitro degradation of heparan sulfate (HS) proteoglycans by HPR1 in pancreatic adenocarcinomas. Loss of cell surface HS suppresses fibroblast growth factor 2-mediated cell signaling and proliferation |
Q44765740 | In vivo hyaluronan synthesis upon expression of the mammalian hyaluronan synthase gene in Drosophila |
Q39304663 | Inhibition of human respiratory syncytial virus infectivity by a dendrimeric heparan sulfate-binding peptide. |
Q42155968 | Involvement of chondroitin sulfate synthase-3 (chondroitin synthase-2) in chondroitin polymerization through its interaction with chondroitin synthase-1 or chondroitin-polymerizing factor |
Q40602026 | Involvement of glycosylphosphatidylinositol-linked ceruloplasmin in the copper/zinc-nitric oxide-dependent degradation of glypican-1 heparan sulfate in rat C6 glioma cells |
Q39253947 | Kidney development and perspectives for organ engineering |
Q24290392 | LDL-receptor-related proteins in Wnt signal transduction |
Q28469158 | LPS responsiveness and neutrophil chemotaxis in vivo require PMN MMP-8 activity |
Q56895736 | Large, tissue-regulated domain diversity of heparan sulfates demonstrated by phage display antibodies |
Q34219410 | Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus |
Q33315465 | Loss of Endocan tumorigenic properties after alternative splicing of exon 2. |
Q28587262 | Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development |
Q44520479 | Major glycosaminoglycan species in the developing retina: synthesis, tissue distribution and effects upon cell death |
Q28588474 | Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate |
Q28587947 | Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation |
Q51848445 | Mapping candidate regions and genes for congenital anomalies of the kidneys and urinary tract (CAKUT) by array-based comparative genomic hybridization. |
Q96222241 | Mature oligodendrocytes bordering lesions limit demyelination and favor myelin repair via heparan sulphate production |
Q38186487 | Mesenchymal stem cells, neural lineage potential, heparan sulfate proteoglycans and the matrix. |
Q91828805 | Metabolic and behavioral parameters of mice with reduced expression of Syndecan-1 |
Q37089817 | Method development and analysis of free HS and HS in proteoglycans from pre- and postmenopausal women: evidence for biosynthetic pathway changes in sulfotransferase and sulfatase enzymes |
Q34170525 | Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers |
Q38296018 | Microarray analysis detects novel Pax3 downstream target genes |
Q50571168 | Modulating Glypican4 suppresses tumorigenicity of embryonic stem cells while preserving self-renewal and pluripotency. |
Q31012211 | Modulations of glypican-1 heparan sulfate structure by inhibition of endogenous polyamine synthesis. Mapping of spermine-binding sites and heparanase, heparin lyase, and nitric oxide/nitrite cleavage sites |
Q36611135 | Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo |
Q24291588 | Molecular cloning and expression of a human chondroitin synthase |
Q42688017 | Molecular cloning and expression of a second chondroitin N-acetylgalactosaminyltransferase involved in the initiation and elongation of chondroitin/dermatan sulfate |
Q38293889 | Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli |
Q57279432 | Morphogen diffusion: the case of the Wingless protein |
Q21245330 | Mutations in many genes affect aggressive behavior in Drosophila melanogaster |
Q40838438 | N-unsubstituted glucosamine in heparan sulfate of recycling glypican-1 from suramin-treated and nitrite-deprived endothelial cells. mapping of nitric oxide/nitrite-susceptible glucosamine residues to clustered sites near the core protein. |
Q52777524 | NDST1 missense mutations in autosomal recessive intellectual disability. |
Q40706633 | NG2 proteoglycan mediates beta1 integrin-independent cell adhesion and spreading on collagen VI. |
Q28298433 | Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate |
Q31109060 | Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes. |
Q52165281 | Notch signaling: Fringe really is a glycosyltransferase. |
Q50573731 | Old gene, new phenotype: mutations in heparan sulfate synthesis enzyme, EXT2 leads to seizure and developmental disorder, no exostoses. |
Q46050552 | On the role of glypicans in the process of morphogen gradient formation |
Q37310377 | On-line separations combined with MS for analysis of glycosaminoglycans |
Q40021244 | Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery |
Q37071636 | Optimized extraction of glycosaminoglycans from normal and osteoarthritic cartilage for glycomics profiling |
Q37169432 | Organ-specific heparan sulfate structural phenotypes. |
Q43748131 | Ovarian carcinoma cells synthesize both chondroitin sulfate and heparan sulfate cell surface proteoglycans that mediate cell adhesion to interstitial matrix |
Q24291309 | Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis |
Q37559582 | Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer |
Q92956166 | Pathophysiology of aged lymphatic vessels |
Q34133514 | Perception of lipo-chitooligosaccharidic Nod factors in legumes |
Q52115466 | Perlecan participates in proliferation activation of quiescent Drosophila neuroblasts. |
Q34122102 | Perspectives on the evolutionary origin of tetrapod limbs. |
Q37889211 | Position matters: variability in the spatial pattern of BMP modulators generates functional diversity |
Q35746811 | Preparation and characterization of heparin hexasaccharide library with N-unsubstituted glucosamine residues |
Q38331584 | Preparation of heparin/heparan sulfate oligosaccharides with internal N-unsubstituted glucosamine residues for functional studies |
Q28277212 | Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growth |
Q44978511 | Production of N-sulfated polysaccharides using yeast-expressed N-deacetylase/N-sulfotransferase-1 (NDST-1). |
Q38680940 | Proteoglycans and axon guidance: a new relationship between old partners |
Q34179324 | Proteoglycans in the nervous system--the quest for functional roles in vivo |
Q34362776 | Proteoglycans: pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland |
Q37745062 | Proteoglycomics: recent progress and future challenges |
Q33237312 | Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis. |
Q39572643 | Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis |
Q34271235 | Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate |
Q34066504 | Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans |
Q24676527 | Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family |
Q36722802 | Redefining the role of syndecans in C. elegans biology |
Q24537749 | Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins |
Q35114376 | Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans |
Q47621324 | Regulation of glycosaminoglycan biogenesis is critical for sensitive-period-dependent vocal ontogeny. |
Q28584264 | Regulation of pancreatic endocrine cell differentiation by sulphated proteoglycans |
Q28582695 | Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney |
Q38523590 | Relationship between sprouting axons, proteoglycans and glial cells following unilateral nigrostriatal axotomy in the adult rat. |
Q36220338 | Role of glycosaminoglycans in infectious disease |
Q36802608 | Role of heparan sulfate in ocular diseases. |
Q34414667 | Role of heparan sulfate proteoglycans in cell signaling and cancer |
Q34017795 | Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila |
Q34989564 | Role of heparan sulfate-2-O-sulfotransferase in the mouse. |
Q37784308 | Roles of heparan sulfate in mammalian brain development current views based on the findings from Ext1 conditional knockout studies |
Q34718195 | Roles of heparan-sulphate glycosaminoglycans in cancer |
Q35697283 | Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function |
Q21144445 | Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival |
Q38031468 | Signaling mechanisms controlling cell fate and embryonic patterning |
Q53060649 | Skeletal dysplasia, global developmental delay, and multiple congenital anomalies in a 5-year-old boy-report of the second family with B3GAT3 mutation and expansion of the phenotype. |
Q30960842 | Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila |
Q57242324 | Software for Peak Finding and Elemental Composition Assignment for Glycosaminoglycan Tandem Mass Spectra |
Q35804497 | Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis |
Q28251561 | Spatiotemporal distribution of heparan sulfate epitopes during murine cartilage growth plate development |
Q42525353 | Spatiotemporal distribution of heparan sulfate epitopes during myogenesis and synaptogenesis: a study in developing mouse intercostal muscle |
Q33317125 | Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation |
Q34103547 | Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression |
Q48439743 | Stem cells that know their place |
Q64252462 | Structural Biology of the FGF7 Subfamily |
Q46135223 | Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis |
Q38336239 | Structural and functional characterization of oversulfated chondroitin sulfate/dermatan sulfate hybrid chains from the notochord of hagfish. Neuritogenic and binding activities for growth factors and neurotrophic factors |
Q27673616 | Structural basis of heparan sulfate-specific degradation by heparinase III |
Q40802141 | Structural characterization of heparan sulfate and chondroitin sulfate of syndecan-1 purified from normal murine mammary gland epithelial cells. Common phosphorylation of xylose and differential sulfation of galactose in the protein linkage region t |
Q33275137 | Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes |
Q34523315 | Structure and biological interactions of heparin and heparan sulfate |
Q48267335 | Structure and elasticity of bush and brush-like models of the endothelial glycocalyx |
Q37533574 | Structure and response to flow of the glycocalyx layer |
Q38666664 | Sulfated glycopeptide nanostructures for multipotent protein activation |
Q42668609 | Sulfated is a negative feedback regulator of wingless in Drosophila |
Q51837891 | Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. |
Q34944523 | Sulfotransferases and sulfated oligosaccharides |
Q51626960 | Suppression of the biological activities of the epidermal growth factor (EGF)-like domain by the heparin-binding domain of heparin-binding EGF-like Growth Factor. |
Q47881177 | Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice |
Q34177237 | Syndecan-1-Dependent Suppression of PDK1/Akt/Bad Signaling by Docosahexaenoic Acid Induces Apoptosis in Prostate Cancer |
Q37008599 | Syndecan-1: a dynamic regulator of the myeloma microenvironment |
Q61918715 | Syndecan-2 downregulation impairs angiogenesis in human microvascular endothelial cells |
Q34250621 | Syndecans and cell adhesion |
Q35611355 | Syndecans: proteoglycan regulators of cell-surface microdomains? |
Q37697058 | Synthesis of fluorophore-tagged xylosides that prime glycosaminoglycan chains |
Q42825962 | Temporal and functional changes in glycosaminoglycan expression during osteogenesis. |
Q34392836 | The Caenorhabditis elegans vulval morphogenesis gene sqv-4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated |
Q47224539 | The Components of Bone and What They Can Teach Us about Regeneration |
Q37810999 | The Dynamic Glycome Microenvironment and Stem Cell Differentiation into Vasculature |
Q28205615 | The SLC26 gene family of multifunctional anion exchangers |
Q24540364 | The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development |
Q22065842 | The Sequence of the Human Genome |
Q52085901 | The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors. |
Q37152815 | The chemical neurobiology of carbohydrates |
Q38059785 | The complex world of WNT receptor signalling |
Q37004231 | The design and synthesis of new synthetic low-molecular-weight heparins |
Q34522475 | The detection of glycosaminoglycans in pancreatic islets and lymphoid tissues |
Q28216354 | The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues |
Q33948367 | The effect of precursor structures on the action of glucosaminyl 3-O-sulfotransferase-1 and the biosynthesis of anticoagulant heparan sulfate |
Q36719459 | The endothelial glycocalyx: composition, functions, and visualization |
Q54532324 | The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. Molecular cloning, recombinant expression, and biochemical characterization. |
Q24300738 | The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway |
Q40668417 | The involvement of heparan sulfate (HS) in FGF1/HS/FGFR1 signaling complex |
Q37171354 | The lens capsule |
Q24671153 | The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins |
Q28575434 | The loss of glypican-3 induces alterations in Wnt signaling |
Q28513833 | The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse |
Q42390629 | The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease |
Q60482229 | The solution structure of heparan sulfate differs from that of heparin: implications for function |
Q35107450 | The solution structure of heparan sulfate differs from that of heparin: implications for function. |
Q36332805 | The structural basis for a coordinated reaction catalyzed by a bifunctional glycosyltransferase in chondroitin biosynthesis |
Q33199519 | The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells |
Q43795211 | The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension |
Q26743361 | Tissue- and Serum-Associated Biomarkers of Hepatocellular Carcinoma |
Q24314953 | Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels |
Q34411574 | Two-step mechanism that determines the donor binding specificity of human UDP-N-acetylhexosaminyltransferase |
Q35219626 | Unlocking the secrets of syndecans: transgenic organisms as a potential key. |
Q33824982 | Unraveling the specificity of heparanase utilizing synthetic substrates |
Q35564095 | Utilization of lectin-histochemistry in forensic neuropathology: lectin staining provides useful information for postmortem diagnosis in forensic neuropathology |
Q52644490 | Variations in the Peritrophic Matrix Composition of Heparan Sulphate from the Tsetse Fly, Glossina morsitans morsitans. |
Q52165379 | Vascular developmental biology: getting nervous. |
Q52128481 | Well developed: the SDB reaches 60. Society for Developmental Biology. |
Q46018207 | Wnt/β-catenin signaling during early vertebrate neural development. |
Q81232514 | [Comparison of the osteogenic activity of bone morphogenetic protein (BMP) mutants] |
Q29618701 | arrow encodes an LDL-receptor-related protein essential for Wingless signalling |
Q33928505 | rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate |
Q24292160 | Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfa |
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