Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses

scientific article

Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1053027325
P356DOI10.1186/1745-6673-6-6
P932PMC publication ID3068988
P698PubMed publication ID21414210
P5875ResearchGate publication ID50419000

P50authorAdam V WisnewskiQ91364881
P2093author name stringJian Liu
Lan Xu
Christina A Herrick
Carrie A Redlich
Eve Robinson
P2860cites workUptake and distribution of 14C during and following inhalation exposure to radioactive toluene diisocyanateQ23909472
Autoradiographic Analyses of Guinea Pig Airway Tissues Following Inhalation Exposure to 14C-Labeled Methyl IsocyanateQ23909832
Distribution and reactivity of inhaled 14C-labeled toluene diisocyanate (TDI) in ratsQ23909833
Asthma death after spraying polyurethane truck bedlinerQ23912001
Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: II. A quantitative assessmentQ23912080
Skin exposure to isocyanates: reasons for concernQ23912082
Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanateQ23912396
Airway hyperreactivity elicited by toluene diisocyanate (TDI)-albumin conjugate is not accompanied by airway eosinophilic infiltration in guinea pigsQ23915581
Inhalation of toluene diisocyanate vapor induces allergic rhinitis in miceQ23923273
Respiratory protection from isocyanate exposure in the autobody repair and refinishing industryQ23924086
Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: III. A personal exposure algorithmQ23924088
Isocyanate vapor-induced antigenicity of human albuminQ24169944
Probability-based protein identification by searching sequence databases using mass spectrometry dataQ27860736
Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanateQ28388975
Recent developments in diisocyanate asthmaQ31143737
Tropomyosin: an invertebrate pan-allergenQ33726794
Albumin: biochemical properties and therapeutic potentialQ36138540
Immunologic and respiratory responses to airway challenges of dogs with toluene diisocyanateQ36597467
Lung/skin connections in occupational lung diseaseQ37100872
Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4.Q37175971
Cytokeratin autoantibodies: useful serologic markers for toluene diisocyanate-induced asthmaQ37205923
Occupational asthma: current concepts in pathogenesis, diagnosis, and managementQ37413591
Determination of isocyanate biomarkers in construction site workersQ39417625
Use of liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) for routine identification of enzymatically digested proteins separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.Q40854093
Overview of diisocyanate occupational asthmaQ41035593
The guinea pig model of diisocyanate sensitization. I. Immunologic studiesQ42245820
An Asthma Model Developed in the Guinea Pig by Intranasal Application of 2,4-Toluene DiisocyanateQ42278098
Dermal and inhalation exposure to methylene bisphenyl isocyanate (MDI) in iron foundry workersQ43270592
A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challengeQ43982686
Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammationQ44438856
Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in miceQ44885235
Multiple challenges in a mouse model of chemical-induced asthma lead to tolerance: ventilatory and inflammatory responses are blunted, immunologic humoral responses are not.Q46158972
Dermal contact with toluene diisocyanate (TDI) produces respiratory tract hypersensitivity in guinea pigsQ46189525
Repeated inhalation challenge with diphenylmethane-4,4'-diisocyanate in brown Norway rats leads to a time-related increase of neutrophils in bronchoalveolar lavage after topical inductionQ46375181
Delayed-type asthmatic response induced by repeated intratracheal exposure to toluene-2,4-diisocyanate in guinea pigsQ46459112
The guinea pig model of diisocyanate sensitization. II. Physiologic studiesQ46475648
Toluene diisocyanate protein adducts in the bronchoalveolar lavage of guinea pigs exposed to vapors of the chemicalQ46532252
Concentration-dependent immunologic response to toluene diisocyanate (TDI) following inhalation exposureQ46569763
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): analysis of the elicitation dose-response relationshipQ46582605
Usage of air monitoring and biomarkers of isocyanate exposure to assess the effect of a control interventionQ46698688
TDI can induce respiratory allergy with Th2-dominated response in miceQ46791769
How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice?Q46916456
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): impact of vehicle for topical inductionQ46928276
A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergyQ47361097
Methods to assess RAST results in patients exposed to chemical allergensQ49246877
Th2 Cytokines in Skin Draining Lymph Nodes and Serum IgE Do Not Predict Airway Hypersensitivity to Intranasal Isocyanate Exposure in Mice.Q51742327
Assessment of respiratory hypersensitivity in guinea pigs sensitized to toluene diisocyanate: improvements on analysis of respiratory response.Q52250521
MASCOT: multiple alignment system for protein sequences based on three-way dynamic programming.Q52398029
Inconsistencies between cytokine profiles, antibody responses, and respiratory hyperresponsiveness following dermal exposure to isocyanates.Q53589788
Immunological determinants of ventilatory changes induced in mice by dermal sensitization and respiratory challenge with toluene diisocyanateQ57010137
Testing for contact allergy in experimental animalsQ69243729
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workersQ69326404
Intra- and intermolecular reactions of 4,4'-diisocyanatodiphenylmethane with human serum albuminQ70075192
Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in miceQ71135018
A murine model for assessing the respiratory hypersensitivity potential of chemical allergensQ71855663
Total IgE Antibody Production in BALB/c Mice after Dermal Exposure to ChemicalsQ72015436
Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergensQ73027746
Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivoQ73286386
Airborne methylene diphenyl diisocyanate (MDI) concentrations associated with the application of polyurethane spray foam in residential constructionQ79647800
Cross-reactivity between storage and dust mites and between mites and shrimpQ82271707
Respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate in guinea pigs: comparison with trimellitic anhydrideQ93923461
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmethylenediphenyldiisocyanate (unspec. isomers)Q107370465
P304page(s)6
P577publication date2011-03-17
P1433published inJournal of Occupational Medicine and ToxicologyQ15756113
P1476titleImmune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses
P478volume6

Reverse relations

cites work (P2860)
Q89892380Analysis of Lung Gene Expression Reveals a Role for Cl- channels in Diisocyanate Induced Airway Eosinophilia in a Mouse Model of Asthma Pathology
Q50848027Analytical determination of specific 4,4'-methylene diphenyl diisocyanate hemoglobin adducts in human blood.
Q38631246Anti-hapten antibodies in response to skin sensitization.
Q36317810Biomonitoring Hexamethylene diisocyanate (HDI) exposure based on serum levels of HDI-specific IgG.
Q77790237Circulating miRs-183-5p, -206-3p and -381-3p may serve as novel biomarkers for 4,4'-methylene diphenyl diisocyanate exposure
Q27968994Development of an interception glove sampler for skin exposures to aromatic isocyanates
Q37998948Diagnosis of occupational asthma: an update.
Q77793527Dilysine-methylene diphenyl diisocyanate (MDI), a urine biomarker of MDI exposure?
Q23909574Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammation
Q28385945Isocyanate exposure assessment combining industrial hygiene methods with biomonitoring for end users of orthopedic casting products
Q36586065Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate
Q27968920Occupational respiratory allergic diseases in healthcare workers
Q32944508Opportunities and obstacles in translating evidence to policy in occupational asthma
Q39238232Oxidative activity of ammonium persulfate salt on mast cells and basophils: implication in hairdressers' asthma
Q23924178Pathogenesis and disease mechanisms of occupational asthma
Q23920668Potential health effects associated with dermal exposure to occupational chemicals
Q57009972Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model

Search more.