Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration

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Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/MOL.113.087106
P8608Fatcat IDrelease_oswcreuqnjcnnf36psacor7e4e
P3181OpenCitations bibliographic resource ID2424957
P932PMC publication ID3781382
P698PubMed publication ID23894151
P5875ResearchGate publication ID253336394

P50authorDrew KiralyQ57931527
Richard MainsQ60057911
Elizabeth A. EipperQ88084756
Taylor P LaReseQ114424812
P2093author name stringM Foster Olive
Seven E Tomek
Natali E Nemirovsky
Stephanie L Yahn
P2860cites workNEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and MemoryQ22241980
Synaptic plasticity and addictionQ22337221
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphologyQ23912227
The genetic basis of addictive disordersQ24607129
Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersQ24632757
Neurocircuitry of addictionQ24647156
Kalirin-7 is required for synaptic structure and functionQ24654628
Cdk5 modulates cocaine reward, motivation, and striatal neuron excitabilityQ28508380
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and functionQ28509168
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5Q28568627
Kalirin Dbl-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanismsQ28568794
Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spinesQ28574973
Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine.Q30490470
Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortexQ31911165
Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine.Q48617102
Effects of ifenprodil on morphine-induced conditioned place preference and spatial learning and memory in rats.Q51027400
Large scale association analysis for drug addiction: results from SNP to gene.Q51272269
Genetic regulation of glutamate receptor ion channelsQ33636674
Kalrn promoter usage and isoform expression respond to chronic cocaine exposureQ33823125
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens.Q33940362
Behavioral and morphological responses to cocaine require kalirin7.Q34009298
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbensQ34086476
Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticityQ34105681
Is there a common molecular pathway for addiction?Q34463226
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbensQ34480282
The neuroscience of natural rewards: relevance to addictive drugs.Q34616127
Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedureQ35103785
A genomewide linkage scan of cocaine dependence and major depressive episode in two populationsQ35356582
Histone H3K9 modifications are a local chromatin event involved in ethanol-induced neuroadaptation of the NR2B geneQ35577727
A role for kalirin in the response of rat medium spiny neurons to cocaineQ36294402
Anatomy and pharmacology of cocaine priming-induced reinstatement of drug seekingQ36328136
REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors.Q36408158
Effects of cocaine and withdrawal on the mouse nucleus accumbens transcriptome.Q36557104
The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behaviorQ36610043
Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens.Q36619133
Intravenous drug self-administration in mice: practical considerations.Q36709307
Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneuronsQ36942813
Glutamate and reinstatementQ37373960
The glutamate homeostasis hypothesis of addictionQ37538517
Synapse pathology in psychiatric and neurologic diseaseQ37738136
Synaptic plasticity, a symphony in GEF.Q37764703
Cocaine-induced metaplasticity in the nucleus accumbens: silent synapse and beyondQ37828239
Molecular substrates of action control in cortico-striatal circuits.Q37894296
Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin'?Q38083388
Identification of a novel variant of the human NR2B gene promoter region and its possible association with schizophreniaQ38359894
Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons.Q40448914
Expression of kalirin, a neuronal GDP/GTP exchange factor of the trio family, in the central nervous system of the adult rat.Q40734793
A silent synapse-based mechanism for cocaine-induced locomotor sensitizationQ41518514
In vivo cocaine experience generates silent synapses.Q41904475
Metaplasticity at single glutamatergic synapsesQ42660966
Increased dendritic spine densities on cortical projection neurons in autism spectrum disordersQ43246437
Evidence for addiction-like behavior in the rat.Q45018179
Potential role of cAMP response element-binding protein in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cellsQ46387499
Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor geneQ48006724
Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.Q48313759
The role of NR2B containing NMDA receptor in place preference conditioned with morphine and natural reinforcers in ratsQ48449981
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcocaineQ41576
P304page(s)582-590
P577publication date2013-07-26
P1433published inMolecular PharmacologyQ1943386
P1476titleConstitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration
P478volume84

Reverse relations

cites work (P2860)
Q26824648Abnormal kalirin signaling in neuropsychiatric disorders.
Q39552753Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7.
Q42369635Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function
Q30407136Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning
Q36772668Mouse and Human Genetic Analyses Associate Kalirin with Ventral Striatal Activation during Impulsivity and with Alcohol Misuse
Q39329885Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs.
Q28084365Synaptic Cytoskeletal Plasticity in the Prefrontal Cortex Following Psychostimulant Exposure
Q33721992Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors

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