scholarly article | Q13442814 |
P819 | ADS bibcode | 2008PLoSO...3.1447W |
P356 | DOI | 10.1371/JOURNAL.PONE.0001447 |
P932 | PMC publication ID | 2180199 |
P698 | PubMed publication ID | 18197257 |
P5875 | ResearchGate publication ID | 5654786 |
P2093 | author name string | Andreas Bergmann | |
Yuan Wang | |||
Ying Li | |||
Dongbin Xu | |||
Ernst Hafen | |||
Zhihong Chen | |||
Christian Werz | |||
P2860 | cites work | The Hallmarks of Cancer | Q221226 |
Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics | Q52171416 | ||
Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. | Q52177458 | ||
In Situ Activation Pattern of Drosophila EGF Receptor Pathway During Development | Q52192958 | ||
Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway | Q52207709 | ||
The emergence of order in the Drosophila pupal retina | Q52453111 | ||
Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. | Q52551521 | ||
Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation | Q52565560 | ||
Sprouty, an intracellular inhibitor of Ras signaling | Q52569025 | ||
A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. | Q53668894 | ||
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor | Q78069495 | ||
The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila | Q36846541 | ||
Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas | Q37252270 | ||
Mis-specified cells die by an active gene-directed process, and inhibition of this death results in cell fate transformation in Drosophila | Q37383561 | ||
The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor | Q39757659 | ||
Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila | Q40982035 | ||
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling | Q40995001 | ||
Ubiquitous expression of sevenless: position-dependent specification of cell fate | Q41260139 | ||
Ommatidial development in Drosophila eye disc fragments | Q41381190 | ||
Giant lens, a gene involved in cell determination and axon guidance in the visual system of Drosophila melanogaster | Q41528680 | ||
vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis | Q42003445 | ||
Notch activation of yan expression is antagonized by RTK/pointed signaling in the Drosophila eye. | Q42673863 | ||
Development of the Drosophila retina, a neurocrystalline lattice | Q43989421 | ||
Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. | Q44687983 | ||
Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain | Q44689071 | ||
Regulation of Drosophila neural development by a putative secreted protein | Q44902624 | ||
A role for wingless in an early pupal cell death event that contributes to patterning the Drosophila eye. | Q45129152 | ||
The Drosophila TGF alpha homolog Spitz acts in photoreceptor recruitment in the developing retina | Q46042874 | ||
A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase | Q46204426 | ||
Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration | Q46626360 | ||
The Drosophila homolog of the putative phosphatidylserine receptor functions to inhibit apoptosis | Q47069969 | ||
Ras promotes cell survival in Drosophila by downregulating hid expression | Q47070193 | ||
The head involution defective gene of Drosophila melanogaster functions in programmed cell death | Q47070937 | ||
The Drosophila gene torso encodes a putative receptor tyrosine kinase | Q47071829 | ||
D-cbl, a negative regulator of the Egfr pathway, is required for dorsoventral patterning in Drosophila oogenesis | Q47072323 | ||
Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation | Q24336399 | ||
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas | Q24624849 | ||
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy | Q27824812 | ||
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7 | Q28146026 | ||
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways | Q28274882 | ||
The Cbl interactome and its functions | Q28277251 | ||
Epidermal growth factor receptor mutations in lung cancer | Q29615474 | ||
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 | Q29617290 | ||
Analysis of genetic mosaics in developing and adult Drosophila tissues | Q29617838 | ||
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation | Q29622825 | ||
A Drosophila analogue of v-Cbl is a dominant-negative oncoprotein in vivo | Q30168862 | ||
D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites. | Q30176514 | ||
Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development. | Q30176591 | ||
Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl | Q30193172 | ||
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
A screen for genes that function downstream of Ras1 during Drosophila eye development. | Q33967357 | ||
Cbl: many adaptations to regulate protein tyrosine kinases | Q34205572 | ||
Inhibition of Drosophila EGF receptor activation by the secreted protein Argos. | Q34303458 | ||
Beyond the RING: CBL proteins as multivalent adapters | Q34405560 | ||
The argos gene encodes a diffusible factor that regulates cell fate decisions in the Drosophila eye. | Q34439501 | ||
Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases | Q35169572 | ||
Signal integration during development: insights from the Drosophila eye. | Q35618173 | ||
Cbl-3-deficient mice exhibit normal epithelial development | Q36138338 | ||
Negative regulation of PTK signalling by Cbl proteins | Q36194521 | ||
Signal transduction and the fate of the R7 photoreceptor in Drosophila | Q36471874 | ||
ARK, the Apaf-1 related killer in Drosophila, requires diverse domains for its apoptotic activity | Q36820100 | ||
The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila | Q36844137 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell differentiation | Q210861 |
Drosophila | Q312154 | ||
cell death | Q2383867 | ||
P304 | page(s) | e1447 | |
P577 | publication date | 2008-01-16 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Drosophila cbl is essential for control of cell death and cell differentiation during eye development | |
P478 | volume | 3 |
Q33528991 | CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases |
Q33826264 | D-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis |
Q33929193 | Endocytic pathway is required for Drosophila Toll innate immune signaling |
Q46578462 | Feedback regulation of RTK signaling in development. |
Q37242772 | Genetic control of programmed cell death (apoptosis) in Drosophila |
Q35989025 | Intracellular trafficking in Drosophila visual system development: a basis for pattern formation through simple mechanisms. |
Q36699882 | Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor. |
Q36197104 | Neuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster. |
Q36560463 | Non-cell autonomous control of apoptosis by ligand-independent Hedgehog signaling in Drosophila |
Q26852269 | Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases |
Q36455731 | Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system |
Q33838124 | Regulation of EGFR and Notch signaling by distinct isoforms of D-cbl during Drosophila development |
Q33619834 | The role of ubiquitylation for the control of cell death in Drosophila |
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