scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1005563195 |
P356 | DOI | 10.1038/35003228 |
P698 | PubMed publication ID | 10646608 |
P50 | author | Josef Penninger | Q1674391 |
Pamela Ohashi | Q56891473 | ||
P2093 | author name string | Y Y Kong | |
T Sasaki | |||
A Wakeham | |||
J Le | |||
I Sarosi | |||
H Nishina | |||
D Bouchard | |||
K Bachmaier | |||
S Lipkowitz | |||
C Krawczyk | |||
S Mariathasan | |||
I Kozieradzki | |||
A Itie | |||
A Oliveira-dos-Santos | |||
P2860 | cites work | Chronic inflammation caused by lymphotoxin is lymphoid neogenesis | Q36366337 |
Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue | Q36404280 | ||
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance | Q40396698 | ||
Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor | Q57185397 | ||
Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells | Q58991849 | ||
Binding of T cell receptor to major histocompatibility complex class II-peptide complexes at the single-cell level results in the induction of antigen unresponsiveness (anergy) | Q67589692 | ||
Primate evolution--in and out of Africa | Q95780651 | ||
Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation | Q22008757 | ||
B lymphocytes express and lose syndecan at specific stages of differentiation | Q24596510 | ||
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones | Q28209894 | ||
Differential T cell costimulatory requirements in CD28-deficient mice | Q28590647 | ||
Adaptors and molecular scaffolds in immune cell signaling | Q28610104 | ||
The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase | Q30193228 | ||
T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. | Q33560835 | ||
Altered thymic positive selection and intracellular signals in Cbl-deficient mice | Q33596728 | ||
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation. | Q34449405 | ||
Positive versus negative signaling by lymphocyte antigen receptors | Q34468852 | ||
Functional management of an antiviral cytotoxic T-cell response | Q35889447 | ||
P433 | issue | 6766 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 211-216 | |
P577 | publication date | 2000-01-01 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | |
P478 | volume | 403 |
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Q37473160 | A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity |
Q35063827 | A model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathway |
Q36370638 | A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase |
Q37588247 | A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. |
Q33951432 | A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation. |
Q36079891 | AIRE and APECED: molecular insights into an autoimmune disease |
Q30427703 | ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation |
Q35664087 | Ablation of Cbl-b provides protection against transplanted and spontaneous tumors |
Q34162136 | Abrogating Cbl-b in effector CD8+ T cells improves the efficacy of adoptive therapy of leukemia in mice |
Q34517906 | Activation and inhibition of lymphocytes by costimulation |
Q33898956 | Adapter proteins in lymphocyte antigen-receptor signaling |
Q34282320 | Adapters in lymphocyte signalling |
Q34044528 | Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase |
Q47936492 | Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies |
Q34409836 | Adoptive transfer of siRNA Cblb-silenced CD8+ T lymphocytes augments tumor vaccine efficacy in a B16 melanoma model |
Q28078650 | Advantages of Extracellular Ubiquitin in Modulation of Immune Responses |
Q36421662 | Alpha-MSH regulates protein ubiquitination in T cells |
Q37370498 | Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus |
Q91322503 | An RNA toolbox for cancer immunotherapy |
Q41547133 | An adenoviral vector encoding dominant negative Cbl lowers the threshold for T cell activation in post-thymic T cells |
Q33746412 | Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b. |
Q82786536 | Animal Models of Inflammatory Bowel Disease |
Q34263452 | Antigen decoding by T lymphocytes: from synapses to fate determination |
Q33937471 | Antigen-specific regulation of T cell-mediated cytokine production |
Q34538693 | Antigen-specific splenic CD4+ and CD8+ regulatory T cells generated via the eye, suppress experimental autoimmune encephalomyelitis either at the priming or at the effector phase |
Q28068981 | Aptamers: A New Technological Platform in Cancer Immunotherapy |
Q34120426 | Autoimmune thyroid disease: new models of cell death in autoimmunity |
Q27676126 | Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b |
Q34405560 | Beyond the RING: CBL proteins as multivalent adapters |
Q26744624 | Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression |
Q54471021 | CBL-B is required for leukemogenesis mediated by BCR-ABL through negative regulation of bone marrow homing |
Q40588827 | CBLB ubiquitin ligase: a major regulator of antifungal immunity |
Q45209871 | CBLB variants in type 1 diabetes and their genetic interaction with CTLA4. |
Q39407691 | CD14 gene silencing alters the microRNA expression profile of RAW264.7 cells stimulated by Brucella melitensis infection. |
Q57289668 | CD28 Signaling via VAV/SLP-76 Adaptors |
Q42169398 | CD28-dependent HIV-1 transcription is associated with Vav, Rac, and NF-kappa B activation |
Q40386654 | CD3ε recruits Numb to promote TCR degradation |
Q24670063 | CD4+CD28- costimulation-independent T cells in multiple sclerosis |
Q42552884 | CD43 regulates the threshold for T cell activation by targeting Cbl functions |
Q37421679 | CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells. |
Q60305294 | CD5, an Undercover Regulator of TCR Signaling |
Q42586718 | CIMT 2014: Next waves in cancer immunotherapy--report on the 12th annual meeting of the Association for Cancer Immunotherapy: May 6–8 2014, Mainz, Germany |
Q90482319 | CIMT 2019: report on the 17th Annual Meeting of the Association for Cancer Immunotherapy |
Q24304461 | CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases |
Q34611954 | CTLA-4 negative signaling via lipid rafts: A new perspective |
Q24310048 | Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins |
Q37003275 | Casitas B-lineage lymphoma b inhibits antigen recognition and slows cell cycle progression at late times during CD4+ T cell clonal expansion |
Q77689842 | Cbl and Cbl-b in T-cell regulation |
Q37283549 | Cbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunity |
Q36138338 | Cbl-3-deficient mice exhibit normal epithelial development |
Q37607147 | Cbl-b Deficiency Mediates Resistance to Programmed Death-Ligand 1/Programmed Death-1 Regulation |
Q36300645 | Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma |
Q37731713 | Cbl-b and itch: key regulators of peripheral T-cell tolerance |
Q81543211 | Cbl-b differentially regulates activation-induced apoptosis in T helper 1 and T helper 2 cells |
Q37748608 | Cbl-b in T-cell activation |
Q40531841 | Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b |
Q28585061 | Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells |
Q33558284 | Cbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation |
Q50958644 | Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells. |
Q36370786 | Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk. |
Q24673177 | Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells |
Q39736375 | Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells by suppressing PI3K/Akt activation and enhancing MEK/ERK activation |
Q34367640 | Cbl-b regulates airway mucosal tolerance to aeroallergen |
Q40904107 | Cbl-b regulates the CD28 dependence of T-cell activation. |
Q30168616 | Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells. |
Q35572346 | Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720. |
Q33948376 | Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex |
Q35735738 | Cbl-b: Roles in T Cell Tolerance, Proallergic T Cell Development, and Cancer Immunity |
Q34474505 | Cbl-c Ubiquitin Ligase Activity Is Increased via the Interaction of Its RING Finger Domain with a LIM Domain of the Paxillin Homolog, Hic 5 |
Q24301400 | Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation |
Q43578123 | Cbl-mediated ubiquitinylation and negative regulation of Vav. |
Q34205572 | Cbl: many adaptations to regulate protein tyrosine kinases |
Q28573498 | Cblb is a major susceptibility gene for rat type 1 diabetes mellitus |
Q41091768 | Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition |
Q38112644 | Cbl‐family proteins as regulators of cytoskeleton‐dependent phenomena |
Q38380126 | Cell regulation by phosphotyrosine-targeted ubiquitin ligases |
Q28771482 | Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation |
Q34192425 | Comparative genomic organization of the cbl genes |
Q34009660 | Contracting the 'mus cells'--does down-sizing suit us for diving into the memory pool? |
Q46736652 | Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis |
Q35940280 | Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b |
Q43077500 | Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection |
Q28587056 | DLGH1 is a negative regulator of T-lymphocyte proliferation |
Q34326683 | DOK3 Negatively Regulates LPS Responses and Endotoxin Tolerance |
Q34568402 | Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses |
Q24336767 | Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling |
Q90354863 | Diacylglycerol kinase ζ (DGKζ) and Casitas b-lineage proto-oncogene b-deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance |
Q42485920 | Differential effects of Cbl and 70Z/3 Cbl on T cell receptor-induced phospholipase Cgamma-1 activity. |
Q28387136 | Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases? |
Q36585041 | Does our current understanding of the molecular basis of immune tolerance predict new therapies for autoimmune disease? |
Q37473165 | Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease |
Q28471948 | Drosophila cbl is essential for control of cell death and cell differentiation during eye development |
Q51039411 | Dysregulation of anergy-related factors involved in regulatory T cells defects in Systemic Lupus Erythematosus patients: Rapamycin and Vitamin D efficacy in restoring regulatory T cells. |
Q33551291 | E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. |
Q35072559 | E3 Ubiquitin Ligase Cbl-b Regulates Thymic-Derived CD4+CD25+ Regulatory T Cell Development by Targeting Foxp3 for Ubiquitination |
Q89207889 | E3 Ubiquitin Ligase c-cbl Inhibits Microglia Activation After Chronic Constriction Injury |
Q35835790 | E3 ligases in T cell anergy--turning immune responses into tolerance |
Q33953086 | E3 ubiquitin ligase Cbl-b in innate and adaptive immunity |
Q50439358 | E3 ubiquitin ligase Cbl-b potentiates the apoptotic action of arsenic trioxide by inhibiting the PI3K/Akt pathway |
Q36070980 | E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity |
Q37672304 | E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation |
Q57369632 | E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury |
Q28750747 | E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance |
Q24813057 | E3 ubiquitin ligases and their control of T cell autoreactivity |
Q35873265 | E3 ubiquitin ligases as T cell anergy factors. |
Q37588591 | E3 ubiquitin ligases in T-cell tolerance |
Q90627972 | Early-onset inflammatory bowel disease as a model disease to identify key regulators of immune homeostasis mechanisms |
Q43225888 | Engineering effective T-cell based antitumor immunity |
Q37260135 | Enhanced T cell apoptosis within Drak2-deficient mice promotes resistance to autoimmunity |
Q34596980 | Enhancement of long-term memory retention and short-term synaptic plasticity in cbl-b null mice. |
Q33577204 | Enhancing CD8 T-cell memory by modulating fatty acid metabolism |
Q28539113 | Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A |
Q79173587 | Establishment and Characterization of the Komeda Diabetes-prone Rat as a Segregating Inbred Strain |
Q38909897 | Exosomes from Dendritic Cells Loaded with Chaperone-Rich Cell Lysates Elicit a Potent T Cell Immune Response Against Intracranial Glioma in Mice |
Q44389555 | Expression and function of Cbl-b in T cells from patients with systemic lupus erythematosus, and detection of the 2126 A/G Cblb gene polymorphism in the Mexican mestizo population. |
Q36990608 | From T-cell activation signals to signaling control of anti-cancer immunity |
Q41369044 | Functional Expression of Programmed Death-Ligand 1 (B7-H1) by Immune Cells and Tumor Cells |
Q35604557 | GRAIL (Gene Related to Anergy in Lymphocytes) Regulates Cytoskeletal Reorganization through Ubiquitination and Degradation of Arp2/3 Subunit 5 and Coronin 1A |
Q37809578 | GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness |
Q28155998 | GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells |
Q37710951 | Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms |
Q35176426 | Genetic analysis of CD28 signaling |
Q28591902 | Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice |
Q26783085 | Genetically engineered mouse models for studying inflammatory bowel disease |
Q36593309 | Genetics of SLE in mice |
Q37839499 | Genome-wide association studies in multiple sclerosis: lessons and future prospects |
Q47434293 | Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation. |
Q37172531 | HLA class II transgenic mice mimic human inflammatory diseases. |
Q33708589 | Human ITCH E3 ubiquitin ligase deficiency causes syndromic multisystem autoimmune disease. |
Q28943483 | Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene |
Q38356890 | Identification of embryonic pancreatic genes using Xenopus DNA microarrays |
Q47774246 | Immune Regulation by Ubiquitin Tagging as Checkpoint Code. |
Q38111096 | Immune modulation by genetic modification of dendritic cells with lentiviral vectors. |
Q35193871 | Immune networks in animal models of inflammatory bowel disease |
Q58570450 | Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch |
Q36328809 | Immunity by ubiquitylation: a reversible process of modification |
Q37864698 | Immunological perspective of self versus tumor antigens: insights from the RIP-gp model. |
Q30680139 | Immunopathogenesis of the multiple sclerosis lesion |
Q36371686 | Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice |
Q51960672 | Impaired T-cell development in the absence of Vav1 and Itk. |
Q82468648 | Increased antigen responsiveness of naive CD8 T cells exposed to IL-7 and IL-21 is associated with decreased CD5 expression |
Q35015130 | Indispensable roles of mammalian Cbl family proteins as negative regulators of protein tyrosine kinase signaling: Insights from in vivo models |
Q40610011 | Inhibition of CBLB protects from lethal Candida albicans sepsis |
Q37677433 | Interruption of OX40L signaling prevents costimulation blockade-resistant allograft rejection |
Q39272758 | Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity |
Q35119897 | Intrinsic T Cell Defects in Systemic Autoimmunity |
Q36608215 | Itch-/- alphabeta and gammadelta T cells independently contribute to autoimmunity in Itchy mice |
Q41920687 | K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling |
Q54245255 | K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation. |
Q34572115 | Knockout mice: a paradigm shift in modern immunology |
Q36252532 | Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b |
Q34111708 | Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy |
Q37230559 | Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia |
Q33912823 | Lymphocyte signaling: Cbl sets the threshold for autoimmunity |
Q34091330 | Lymphocytes with a complex: adapter proteins in antigen receptor signaling |
Q47757131 | Lys63-polyubiquitination by the E3 ligase casitas B-lineage lymphoma-b (Cbl-b) modulates peripheral regulatory T cell tolerance in patients with systemic lupus erythematosus. |
Q38040302 | MODULATING CO-STIMULATION DURING ANTIGEN PRESENTATION TO ENHANCE CANCER IMMUNOTHERAPY. |
Q35119907 | Major Peptide Autoepitopes for Nucleosome‐Centered T and B Cell Interaction in Human and Murine Lupus |
Q34987286 | Making and breaking tolerance. |
Q35045888 | Many paths lead to lupus. |
Q54256455 | Mechanisms of Tolerance Induction by Dendritic Cells In Vivo |
Q28190356 | Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome |
Q26852975 | MicroRNA regulation of lymphocyte tolerance and autoimmunity |
Q37696126 | MicroRNA-891b is an independent prognostic factor of pancreatic cancer by targeting Cbl-b to suppress the growth of pancreatic cancer cells |
Q38393275 | Modulation of Immune Cell Functions by the E3 Ligase Cbl-b. |
Q37465464 | Modulation of peripheral B cell tolerance by CD72 in a murine model |
Q41536641 | Modulation of the spleen transcriptome in domestic turkey (Meleagris gallopavo) in response to aflatoxin B1 and probiotics |
Q37049512 | Molecular and cellular mechanisms of photocarcinogenesis |
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Q36870857 | Molecular mechanisms of CD4+ T-cell anergy |
Q38098621 | Molecular mechanisms of T-cell anergy |
Q33753720 | Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy |
Q37864696 | Molecular mechanisms of T-cell tolerance. |
Q35463260 | Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment |
Q36466372 | Molecular regulation of T-cell anergy |
Q34262298 | Molecular underpinning of B-cell anergy |
Q28307750 | Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders |
Q54642331 | Myeloid Leukemia Development in c-Cbl RING Finger Mutant Mice Is Dependent on FLT3 Signaling |
Q36622748 | NFAT transcription factors in control of peripheral T cell tolerance. |
Q33784244 | Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression |
Q36839507 | Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2. |
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Q34236595 | Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase. |
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Q35145782 | Negative regulation of TCR signaling and T-cell activation by selective protein degradation |
Q44808755 | New autoimmune genes and the pathogenesis of type 1 diabetes |
Q28608965 | New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway |
Q37899120 | Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells |
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Q35549999 | Notch signaling in the immune system. |
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Q35899482 | Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation. |
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Q42160561 | Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins |
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Q35181798 | Phosphoinositide 3-kinase signalling--which way to target? |
Q33656136 | Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance |
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Q51039264 | Polymorphic variation in the CBLB gene in human type 1 diabetes |
Q34572179 | Positive and negative regulation of T-cell activation by adaptor proteins |
Q38624562 | Post-Translational Modification Profiling-Functional Proteomics for the Analysis of Immune Regulation. |
Q36382352 | Progress in multiple sclerosis genetics |
Q36177042 | Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation |
Q26852269 | Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases |
Q34088521 | Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells. |
Q26853207 | RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis |
Q37155467 | Rapid microtubule-dependent induction of neurite-like extensions in NIH 3T3 fibroblasts by inhibition of ROCK and Cbl |
Q33588711 | Re-adapting T cells for cancer therapy: from mouse models to clinical trials |
Q38711461 | Receptor signaling in immune cell development and function |
Q35126405 | Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes |
Q50534081 | Redirection to the bone marrow improves T cell persistence and antitumor functions. |
Q46367310 | Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels |
Q36508910 | Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins |
Q57817463 | Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b |
Q34987659 | Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications |
Q37256999 | Regulation of T-cell responses by PTEN |
Q39029996 | Regulation of TGF-β Family Signaling by Inhibitory Smads. |
Q28587191 | Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2 |
Q36228270 | Regulation of peripheral T cell activation by calreticulin |
Q40723397 | Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase |
Q35084280 | Regulation of thymocyte development: only the meek survive |
Q37412624 | Regulatory T cells overturned: the effectors fight back |
Q39188794 | Relationship between CD4 Regulatory T Cells and Anergy In Vivo |
Q21285001 | Releasing the Brake: Targeting Cbl-b to Enhance Lymphocyte Effector Functions |
Q38363901 | Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation |
Q36922987 | Role of phosphoinositide 3-kinase signaling in autoimmunity |
Q33781079 | Roles of E3 ubiquitin ligases in cell adhesion and migration |
Q35571851 | Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling. |
Q53667349 | Selective inhibition of Fcepsilon RI-mediated mast cell activation by a truncated variant of Cbl-b related to the rat model of type 1 diabetes mellitus |
Q34187562 | Sin: good or bad? A T lymphocyte perspective |
Q30496974 | Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization |
Q34632056 | Spinning molecular immunology into successful immunotherapy |
Q36229277 | Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells |
Q46124218 | Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex |
Q38721532 | Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene. |
Q33745662 | Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase |
Q37087575 | T cell Receptor Signal Transduction in T lymphocytes |
Q24658051 | T cell activation |
Q36986111 | T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells |
Q36369516 | T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase |
Q37173926 | T cell sensitivity to TGF-beta is required for the effector function but not the generation of splenic CD8+ regulatory T cells induced via the injection of antigen into the anterior chamber |
Q37783748 | T follicular helper cells during immunity and tolerance. |
Q34567937 | T lymphocyte activation--an inside overview. |
Q38103582 | T-Cell Tolerance in Cancer |
Q35624722 | T-cell anergy: from phenotype to genotype and back |
Q39150603 | T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation |
Q36498083 | T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b |
Q34093298 | T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency |
Q24646289 | T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain |
Q34716347 | T-cell signalling and autoimmunity: molecular mechanisms of disease |
Q35998853 | T-helper cell intrinsic defects in lupus that break peripheral tolerance to nuclear autoantigens |
Q57184989 | TCR affinity and negative regulation limit autoimmunity |
Q80143450 | TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis |
Q37155730 | Targeting CBLB as a potential therapeutic approach for disseminated candidiasis |
Q28277251 | The Cbl interactome and its functions |
Q33357894 | The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. |
Q33802637 | The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cells |
Q36791340 | The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance |
Q24320362 | The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination |
Q34299184 | The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival |
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