scholarly article | Q13442814 |
P2093 | author name string | Adam J Adler | |
Adam T Hagymasi | |||
Harry Z Qui | |||
Marianne A Mihalyo | |||
Marie-Clare St Rose | |||
Robert B Clark | |||
Suman Bandyopadhyay | |||
P2860 | cites work | Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins | Q24310048 |
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity | Q24643886 | ||
Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells | Q24653129 | ||
Innate immune recognition | Q27860721 | ||
Projection of an immunological self shadow within the thymus by the aire protein | Q28207164 | ||
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus | Q28573498 | ||
Tolerance, danger, and the extended family | Q29547532 | ||
The Fas death factor | Q29620461 | ||
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo | Q30080006 | ||
Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells. | Q30168616 | ||
In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy | Q33756565 | ||
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice | Q45854348 | ||
Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity | Q46094710 | ||
Adjuvant effect of IL-12: conversion of peptide antigen administration from tolerizing to immunizing for CD8+ T cells in vivo. | Q52032514 | ||
IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells | Q52267043 | ||
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. | Q55035366 | ||
CTLA-4 engagement acts as a brake on CD4+ T cell proliferation and cytokine production but is not required for tuning T cell reactivity in adaptive tolerance | Q56903158 | ||
T cell tolerance by clonal elimination in the thymus | Q56922465 | ||
Direct evidence that functionally impaired CD4+ T cells persist in vivo following induction of peripheral tolerance | Q58882235 | ||
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
T-cell apoptosis detected in situ during positive and negative selection in the thymus | Q59087078 | ||
Distinct Requirements for Deletion versus Anergy during CD8 T Cell Peripheral Tolerance In Vivo | Q61140313 | ||
CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction | Q61140374 | ||
Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation | Q68261487 | ||
In vivo CD4+ T cell tolerance induction versus priming is independent of the rate and number of cell divisions | Q73330334 | ||
Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion | Q73406538 | ||
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide | Q73688337 | ||
CD4 cell priming and tolerization are differentially programmed by APCs upon initial engagement | Q74145423 | ||
CD4+ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis | Q80455078 | ||
Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials | Q33756571 | ||
Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells | Q33756646 | ||
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen | Q33756662 | ||
T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression | Q33756668 | ||
Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation | Q33756678 | ||
Effector CD4 cells are tolerized upon exposure to parenchymal self-antigen | Q33791198 | ||
Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigen | Q33791226 | ||
Regulatory T cells: key controllers of immunologic self-tolerance | Q33941140 | ||
Transcriptional mechanisms underlying lymphocyte tolerance. | Q34135663 | ||
In vivo activation of antigen-specific CD4 T cells. | Q34178091 | ||
Immune responses against the myelin/oligodendrocyte glycoprotein in experimental autoimmune demyelination | Q34279716 | ||
In vivo instruction of suppressor commitment in naive T cells | Q34548023 | ||
T-cell signalling and autoimmunity: molecular mechanisms of disease | Q34716347 | ||
Peripheral selection of the T cell repertoire | Q34880495 | ||
T cell anergy | Q35019694 | ||
The role of CD95 in the regulation of peripheral T-cell apoptosis | Q35129712 | ||
E3 ubiquitin ligases as T cell anergy factors. | Q35873265 | ||
Peripheral tolerance of CD8 T lymphocytes | Q36076297 | ||
Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo | Q36353340 | ||
Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells | Q36356623 | ||
Certified professionals: CD4(+)CD25(+) suppressor T cells | Q36369181 | ||
Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism | Q36392973 | ||
CD4+ T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells | Q36400881 | ||
Major Histocompatibility Complex Class I–restricted Cross-presentation Is Biased towards High Dose Antigens and Those Released during Cellular Destruction | Q36401408 | ||
Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b | Q36773147 | ||
Casitas B-lineage lymphoma b inhibits antigen recognition and slows cell cycle progression at late times during CD4+ T cell clonal expansion | Q37003275 | ||
New insights into the molecular basis of T cell anergy: anergy factors, avoidance sensors, and epigenetic imprinting | Q37506953 | ||
Egr-2 and Egr-3 are negative regulators of T cell activation. | Q38327900 | ||
Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor. | Q40110921 | ||
Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo | Q40327455 | ||
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen | Q40701079 | ||
Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
Maintenance of in vivo tolerance by persistence of antigen | Q41828244 | ||
Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor | Q41902311 | ||
Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response | Q43986613 | ||
Resistance to CD4+CD25+ regulatory T cells and TGF-beta in Cbl-b-/- mice | Q44240372 | ||
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes | Q44851100 | ||
Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction. | Q45179048 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 4975-4983 | |
P577 | publication date | 2009-10-01 | |
P1433 | published in | Journal of Immunology | Q3521441 |
P1476 | title | The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cells | |
P478 | volume | 183 |
Q34162136 | Abrogating Cbl-b in effector CD8+ T cells improves the efficacy of adoptive therapy of leukemia in mice |
Q33746412 | Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b. |
Q47774246 | Immune Regulation by Ubiquitin Tagging as Checkpoint Code. |
Q38124036 | The role of ubiquitin ligases in the control of organ specific autoimmunity |
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