| scholarly article | Q13442814 |
| P50 | author | David Hildeman | Q43178790 |
| P2093 | author name string | Joseph T Opferman | |
| Pulak Tripathi | |||
| Sema Kurtulus | |||
| P2860 | cites work | In vivo state of antiviral CTL precursors. Characterization of a cycling cell population containing CTL precursors in immune mice. | Q52054498 |
| Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo | Q52057633 | ||
| Negative regulation of the forkhead transcription factor FKHR by Akt. | Q52535267 | ||
| Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis | Q52547440 | ||
| IL-15 regulates CD8+ T cell contraction during primary infection. | Q53643520 | ||
| Bim and Bcl-2 Mutually Affect the Expression of the Other in T Cells | Q56921998 | ||
| Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis | Q56922123 | ||
| bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship | Q57338704 | ||
| Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines | Q57589060 | ||
| Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
| Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo | Q63408405 | ||
| Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease | Q64375577 | ||
| Following a diabetogenic T cell from genesis through pathogenesis | Q70488192 | ||
| Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice | Q70527814 | ||
| Mechanisms of peripheral T cell deletion: anergized T cells are Fas resistant but undergo proliferation-associated apoptosis | Q71425875 | ||
| The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice | Q71678868 | ||
| Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice | Q73296821 | ||
| Bcl-2 controls dendritic cell longevity in vivo | Q74754628 | ||
| Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis | Q77399293 | ||
| Ascorbic acid is a potent inhibitor of various forms of T cell apoptosis | Q77840725 | ||
| IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization | Q81245741 | ||
| Regulatory phosphorylation of Bim: sorting out the ERK from the JNK | Q81833475 | ||
| Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 | ||
| Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 | ||
| Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
| Bim: a novel member of the Bcl-2 family that promotes apoptosis | Q24532974 | ||
| Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters | Q24645192 | ||
| Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes | Q24651802 | ||
| The structure of a Bcl-xL/Bim fragment complex: implications for Bim function | Q27642185 | ||
| BAX activation is initiated at a novel interaction site | Q27652635 | ||
| Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis | Q27734734 | ||
| BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members | Q28118771 | ||
| Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
| Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1 | Q28142184 | ||
| betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis | Q28306984 | ||
| Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells | Q28505374 | ||
| Bcl-2 Rescues T Lymphopoiesis, but Not B or NK Cell Development, in Common γ Chain–Deficient Mice | Q28513706 | ||
| Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice | Q28513839 | ||
| Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation | Q28576927 | ||
| Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair | Q28586758 | ||
| Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis | Q28587336 | ||
| Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim | Q28587387 | ||
| Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis | Q28588677 | ||
| Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis | Q28589263 | ||
| Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice | Q28593186 | ||
| Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis | Q30080034 | ||
| Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B | Q33243937 | ||
| Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim | Q33715752 | ||
| Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
| Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2. | Q33838448 | ||
| Apoptosis and the homeostatic control of immune responses | Q34023771 | ||
| Cutting Edge: Limiting amounts of IL-7 do not control contraction of CD4+ T cell responses | Q34023803 | ||
| Control of Bcl-2 expression by reactive oxygen species | Q34390190 | ||
| Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory | Q34464549 | ||
| Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. | Q34545142 | ||
| T cell apoptosis and reactive oxygen species | Q34835627 | ||
| BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak | Q35079498 | ||
| The CD95(APO-1/Fas) DISC and beyond | Q35091401 | ||
| FoxOs at the crossroads of cellular metabolism, differentiation, and transformation | Q35770614 | ||
| Roles of alpha beta and gamma delta T cell subsets in viral immunity | Q35876930 | ||
| Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection | Q35880244 | ||
| Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor | Q36082833 | ||
| Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells | Q36228932 | ||
| Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis | Q36314636 | ||
| Cell growth cycle block of T cell hybridomas upon activation with antigen | Q36352402 | ||
| Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo | Q36368472 | ||
| Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells | Q36369731 | ||
| CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. | Q36370844 | ||
| Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4 | Q36380382 | ||
| Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice | Q36399348 | ||
| Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice | Q36407358 | ||
| Proapoptotic Bcl-2 family member Bim promotes persistent infection and limits protective immunity | Q36483578 | ||
| Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity | Q36501636 | ||
| Multisite phosphorylation regulates Bim stability and apoptotic activity | Q36756298 | ||
| Exploring regulatory mechanisms of CD8+ T cell contraction | Q36946510 | ||
| IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response | Q36948598 | ||
| Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity | Q36955782 | ||
| The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins | Q37309119 | ||
| Control of mitochondrial apoptosis by the Bcl-2 family | Q37385623 | ||
| Massive Expansion of Antigen-Specific CD8+ T Cells during an Acute Virus Infection | Q37419599 | ||
| Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1. | Q37473351 | ||
| Antioxidant treatment reduces expansion and contraction of antigen-specific CD8+ T cells during primary but not secondary viral infection | Q37567905 | ||
| p53 and E2f: partners in life and death | Q37602510 | ||
| Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors | Q39457731 | ||
| Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover | Q40606380 | ||
| Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. | Q40626751 | ||
| Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis | Q40647484 | ||
| Oxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons. | Q40668530 | ||
| Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. | Q40717909 | ||
| Immunological memory and protective immunity: understanding their relation | Q40969823 | ||
| Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses. | Q41030813 | ||
| Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) | Q41371079 | ||
| The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster | Q41471760 | ||
| BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. | Q41837676 | ||
| Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells | Q41911200 | ||
| Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene. | Q42155614 | ||
| Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection | Q42284303 | ||
| Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells | Q42486244 | ||
| Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice | Q42789442 | ||
| Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. | Q42830166 | ||
| Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis | Q42833059 | ||
| c-Cbl is not required for ERK1/2-dependent degradation of BimEL. | Q43098314 | ||
| Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction | Q43493690 | ||
| Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. | Q43561629 | ||
| CD4 T cell-dependent CD8 T cell maturation | Q43682299 | ||
| Caspase-dependent and -independent T-cell death pathways in pathogenic simian immunodeficiency virus infection: relationship to disease progression | Q45710670 | ||
| Bystander virus infection prolongs activated T cell survival | Q45750055 | ||
| Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. | Q46925453 | ||
| Role of cell cycle regulator E2F1 in regulating CD8 T cell responses during acute and chronic viral infection | Q47318933 | ||
| Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation | Q47915031 | ||
| Immunological adjuvants promote activated T cell survival via induction of Bcl-3. | Q48367905 | ||
| Constitutive expression of IL-7 receptor alpha does not support increased expansion or prevent contraction of antigen-specific CD4 or CD8 T cells following Listeria monocytogenes infection | Q51966846 | ||
| Molecular signature of CD8+ T cell exhaustion during chronic viral infection | Q51970485 | ||
| The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes | Q51991912 | ||
| Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells | Q52004225 | ||
| Molecular and functional profiling of memory CD8 T cell differentiation. | Q52008481 | ||
| Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection | Q52040078 | ||
| Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection | Q52040367 | ||
| P304 | page(s) | 54-67 | |
| P577 | publication date | 2010-07-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | Contracting the 'mus cells'--does down-sizing suit us for diving into the memory pool? | |
| P478 | volume | 236 |
| Q33607668 | Aging of the CD4 T Cell Compartment |
| Q36388507 | B7-H1 limits the entry of effector CD8+T cells to the memory pool by upregulating Bim |
| Q41063742 | BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory. |
| Q42980651 | Bcl-2 allows effector and memory CD8+ T cells to tolerate higher expression of Bim. |
| Q39277476 | Dying to protect: cell death and the control of T-cell homeostasis. |
| Q47808360 | Effect of aging on sputum inflammation and asthma control |
| Q28741958 | Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy |
| Q27022786 | Homeostasis and function of regulatory T cells in aging |
| Q41772001 | Mcl-1 antagonizes Bax/Bak to promote effector CD4+ and CD8+ T-cell responses |
| Q36626949 | Mcl-1 regulates effector and memory CD8 T-cell differentiation during acute viral infection. |
| Q88886742 | Memory responses of innate lymphocytes and parallels with T cells |
| Q36211448 | PP2A-dependent control of transcriptionally active FOXO3a in CD8(+) central memory lymphocyte survival requires p47(phox). |
| Q33826867 | Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection |
| Q40573313 | Response to self antigen imprints regulatory memory in tissues |
| Q90317657 | T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate |
| Q35090375 | Terminating the immune response |
| Q39865491 | miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. |
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