scholarly article | Q13442814 |
P2093 | author name string | Hamid Band | |
Simon J Cook | |||
Ceri M Wiggins | |||
P2860 | cites work | Proteolysis: from the lysosome to ubiquitin and the proteasome | Q81354981 |
Regulatory phosphorylation of Bim: sorting out the ERK from the JNK | Q81833475 | ||
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 | ||
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL | Q24306894 | ||
Bim: a novel member of the Bcl-2 family that promotes apoptosis | Q24532974 | ||
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas | Q24624849 | ||
Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase | Q27617539 | ||
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1 | Q28142184 | ||
The Cbl interactome and its functions | Q28277251 | ||
Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl | Q28564996 | ||
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release | Q28567073 | ||
The Bcl2 family: regulators of the cellular life-or-death switch | Q29614982 | ||
A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin | Q29618006 | ||
The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation | Q30175273 | ||
Altered thymic positive selection and intracellular signals in Cbl-deficient mice | Q33596728 | ||
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
The proteasome as a target for cancer therapy. | Q34286144 | ||
Proteasome inhibitors: from research tools to drug candidates | Q34341985 | ||
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins | Q34612753 | ||
c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses | Q36280423 | ||
Life in the balance: how BH3-only proteins induce apoptosis. | Q36294226 | ||
Bim is a suppressor of Myc-induced mouse B cell leukemia | Q37647369 | ||
Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor | Q40164535 | ||
Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. | Q40323778 | ||
Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. | Q40446996 | ||
Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL. | Q40454938 | ||
Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM. | Q40479135 | ||
Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins | Q40528952 | ||
Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover | Q40606380 | ||
Role of Bim in the survival pathway induced by Raf in epithelial cells | Q40607194 | ||
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. | Q40626751 | ||
Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis | Q40646939 | ||
Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis | Q40647484 | ||
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. | Q40662652 | ||
Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways | Q40666435 | ||
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons | Q42918105 | ||
Nucleotide-binding Oligomerization Domain-1 and Epidermal Growth Factor Receptor | Q61398472 | ||
P433 | issue | 12 | |
P1104 | number of pages | 7 | |
P304 | page(s) | 2605-2611 | |
P577 | publication date | 2007-08-23 | |
P1433 | published in | Cellular Signalling | Q1524097 |
P1476 | title | c-Cbl is not required for ERK1/2-dependent degradation of BimEL. | |
P478 | volume | 19 |
Q37605160 | Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics |
Q33797357 | Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival |
Q37883974 | Bim: Guardian of Tissue Homeostasis and Critical Regulator of the Immune System, Tumorigenesis and Bone Biology |
Q34009660 | Contracting the 'mus cells'--does down-sizing suit us for diving into the memory pool? |
Q50316561 | Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis |
Q24299252 | Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection |
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Q39575518 | Targeting the Regulatory Machinery of BIM for Cancer Therapy |
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Q37381217 | The role of the ubiquitin proteasome system in ischemia and ischemic tolerance |
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