| scholarly article | Q13442814 |
| P50 | author | Gary M Wildey | Q57401714 |
| P2093 | author name string | Philip H Howe | |
| Sneha Ramesh | |||
| P2860 | cites work | PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 |
| TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation | Q24291517 | ||
| Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 | ||
| Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function | Q24294552 | ||
| Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
| ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL | Q24306894 | ||
| No death without life: vital functions of apoptotic effectors | Q24319057 | ||
| RACK1 and CIS mediate the degradation of BimEL in cancer cells | Q24322936 | ||
| JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis | Q24554008 | ||
| The mitochondrial ARTS protein promotes apoptosis through targeting XIAP | Q24610254 | ||
| The Bcl-2 apoptotic switch in cancer development and therapy | Q24620437 | ||
| Mechanisms underlying ubiquitination | Q27860656 | ||
| Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
| Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis | Q28139074 | ||
| The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex | Q28141249 | ||
| Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim | Q28201672 | ||
| Smad4-independent, PP2A-dependent apoptotic effect of exogenous transforming growth factor beta 1 in lymphoma cells | Q28237286 | ||
| Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl | Q28564996 | ||
| Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation | Q28576927 | ||
| Transforming growth factor-beta-mediated tumor necrosis factor-related apoptosis-inducing ligand expression and apoptosis in hepatoma cells requires functional cooperation between Smad proteins and activator protein-1. | Q39958708 | ||
| Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim. | Q39977634 | ||
| Identification of the gene transcription and apoptosis mediated by TGF-beta-Smad2/3-Smad4 signaling | Q40062431 | ||
| Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis | Q40243666 | ||
| Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. | Q40323778 | ||
| Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins | Q40528952 | ||
| Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover | Q40606380 | ||
| Role of Bim in the survival pathway induced by Raf in epithelial cells | Q40607194 | ||
| Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. | Q40626751 | ||
| Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis | Q40647484 | ||
| Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. | Q40662652 | ||
| Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes | Q40663965 | ||
| Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways | Q40666435 | ||
| Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction | Q42487657 | ||
| Novel pro-survival functions of the Kruppel-like transcription factor Egr2 in promotion of macrophage colony-stimulating factor-mediated osteoclast survival downstream of the MEK/ERK pathway. | Q42523643 | ||
| Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage | Q42808536 | ||
| FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons | Q42918105 | ||
| c-Cbl is not required for ERK1/2-dependent degradation of BimEL. | Q43098314 | ||
| Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death. | Q46958357 | ||
| TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase | Q77342591 | ||
| Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies | Q79370601 | ||
| Regulation of Bim by TCR signals in CD4/CD8 double-positive thymocytes | Q80405427 | ||
| Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer | Q29616379 | ||
| ER stress triggers apoptosis by activating BH3-only protein Bim | Q29617730 | ||
| Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells | Q30479990 | ||
| FOXOs, cancer and regulation of apoptosis | Q33642512 | ||
| Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis | Q33913785 | ||
| Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells | Q34124193 | ||
| Non-Smad TGF-beta signals | Q34443708 | ||
| Mechanisms of TGF-beta-mediated apoptosis | Q34505463 | ||
| TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility | Q34713446 | ||
| The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis | Q34718167 | ||
| Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. | Q34732045 | ||
| Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. | Q35075545 | ||
| Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty | Q35139549 | ||
| Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression | Q35663874 | ||
| N-terminal ubiquitination: more protein substrates join in. | Q35727083 | ||
| The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells | Q35745742 | ||
| The role of BH3-only proteins in the immune system | Q36047162 | ||
| Dual role for TGF-beta1 in apoptosis | Q36055872 | ||
| Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis. | Q36241249 | ||
| Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways | Q36274956 | ||
| Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells | Q36371743 | ||
| BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway | Q36403102 | ||
| Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation | Q36516034 | ||
| p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription | Q36742571 | ||
| Multisite phosphorylation regulates Bim stability and apoptotic activity | Q36756298 | ||
| TGF-beta signaling: a tale of two responses | Q36923146 | ||
| Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels | Q36946423 | ||
| TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2 | Q36946967 | ||
| How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? | Q37100016 | ||
| Living with death: the evolution of the mitochondrial pathway of apoptosis in animals. | Q37152726 | ||
| Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2. | Q37257648 | ||
| Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity. | Q37593642 | ||
| Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation | Q38351218 | ||
| Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors | Q39457731 | ||
| P433 | issue | 1 | |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 11-17 | |
| P577 | publication date | 2009-01-30 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Cell Cycle | Q1254166 |
| P1476 | title | Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim | |
| P478 | volume | 8 |
| Q42509946 | A Smad3-PTEN regulatory loop controls proliferation and apoptotic responses to TGF-β in mouse endometrium. |
| Q37478547 | Adenovirus E1A and E1B-19K proteins protect human hepatoma cells from transforming growth factor beta1-induced apoptosis |
| Q39351352 | BHLH transcription factor DEC2 regulates pro-apoptotic factor Bim in human oral cancer HSC-3 cells |
| Q41839747 | Caveolin-1 abrogates TGF-β mediated hepatocyte apoptosis |
| Q42726500 | Efavirenz and 8-hydroxyefavirenz induce cell death via a JNK- and BimEL-dependent mechanism in primary human hepatocytes |
| Q64226399 | Estivation-responsive microRNAs in a hypometabolic terrestrial snail |
| Q92690641 | Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis |
| Q39368735 | Evaluation of amniotic mesenchymal cell derivatives on cytokine production in equine alveolar macrophages: an in vitro approach to lung inflammation. |
| Q34034776 | GO-Bayes: Gene Ontology-based overrepresentation analysis using a Bayesian approach |
| Q47687459 | Glycyrrhetinic Acid Functionalized Graphene Oxide for Mitochondria Targeting and Cancer Treatment In Vivo |
| Q35527180 | In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells |
| Q33705348 | Natural killer cell development and maturation in aged mice. |
| Q40635296 | Nature and mechanisms of hepatocyte apoptosis induced by D-galactosamine/lipopolysaccharide challenge in mice |
| Q33694667 | Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β |
| Q42074762 | Phosphorylation and ubiquitination of degron proximal residues are essential for class II transactivator (CIITA) transactivation and major histocompatibility class II expression |
| Q42096961 | Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system |
| Q64915718 | Prompt apoptotic response to high glucose in SGLT-expressing renal cells. |
| Q37775417 | Resistance to transforming growth factor β-mediated tumor suppression in melanoma: are multiple mechanisms in place? |
| Q36027160 | RhoB upregulation leads to either apoptosis or cytostasis through differential target selection. |
| Q28081170 | Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review) |
| Q33674328 | Smad signaling in skeletal development and regeneration |
| Q28083107 | TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis |
| Q39155151 | Targeting TGF-β Signaling for Therapeutic Gain |
| Q104795035 | Targeting TGFβ signal transduction for cancer therapy |
| Q36462348 | Targeting the TGFβ signalling pathway in disease |
| Q38616577 | The Molecular Influence of Graphene and Graphene Oxide on the Immune System Under In Vitro and In Vivo Conditions. |
| Q92923287 | The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases |
| Q51913616 | The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation |
| Q41226027 | The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis |
| Q33607396 | The tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma. |
| Q92132396 | Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection |
| Q42081850 | Tumor necrosis factor-α-mediated suppression of dual-specificity phosphatase 4: crosstalk between NFκB and MAPK regulates endothelial cell survival |
| Q36381117 | Validation of Expression Patterns for Nine miRNAs in 204 Lymph-Node Negative Breast Cancers |
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