scholarly article | Q13442814 |
P50 | author | Sandra S. Zinkel | Q91232359 |
P2093 | author name string | Wasif N Khan | |
Bonnie B Blomberg | |||
Daniela Frasca | |||
Sarah Alter | |||
Jacqueline A Wright | |||
Richard L Riley | |||
Michelle Ratliff | |||
Kelly McAvoy | |||
P2860 | cites work | B lymphocytes express and lose syndecan at specific stages of differentiation | Q24596510 |
CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche | Q24657562 | ||
Aging up-regulates expression of inflammatory mediators in mouse adipose tissue | Q28249416 | ||
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease | Q28513752 | ||
The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain | Q28594115 | ||
A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice | Q35153782 | ||
Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim | Q35320797 | ||
The transition of pre-BI to pre-BII cells is dependent on the VH structure of the mu/surrogate L chain receptor | Q35846753 | ||
Molecular mechanisms of TNF-alpha-induced apoptosis in aging human T cell subsets | Q36060190 | ||
A molecular mechanism for TNF-α-mediated downregulation of B cell responses | Q36979267 | ||
In senescence, age‐associated B cells secrete TNFα and inhibit survival of B‐cell precursors* | Q37026934 | ||
NK cells in the CD19- B220+ bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursors | Q37345121 | ||
Deviation of the B cell pathway in senescent mice is associated with reduced surrogate light chain expression and altered immature B cell generation, phenotype, and light chain expression | Q37359108 | ||
B cells and aging: molecules and mechanisms | Q37398750 | ||
Impaired B lymphopoiesis in old age: a role for inflammatory B cells? | Q37679476 | ||
B lymphocyte-specific, Cre-mediated mutagenesis in mice | Q39719513 | ||
Pre-B cell receptor assesses the quality of IgH chains and tunes the pre-B cell repertoire by delivering differential signals | Q40247901 | ||
Differential involvement of the transcription factor Blimp-1 in T cell-independent and -dependent B cell differentiation to plasma cells. | Q40943970 | ||
Pre-B cell receptor-mediated selection of pre-B cells synthesizing functional mu heavy chains | Q41015079 | ||
EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes | Q41101434 | ||
A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines | Q41536897 | ||
Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis | Q44633425 | ||
Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover | Q44968876 | ||
A selective increase in the generation of phosphorylcholine-specific B cells associated with aging | Q44989930 | ||
Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta | Q46116890 | ||
Senescent BALB/c mice exhibit decreased expression of lambda5 surrogate light chains and reduced development within the pre-B cell compartment | Q52182767 | ||
Expression and ontogeny of CD2 on murine B cells. | Q53508396 | ||
Repertoire diversity of antibody response to bacterial antigens in aged mice. II. Phosphorylcholine-antibody in young and aged mice differ in both VH/VL gene repertoire and in specificity | Q68011978 | ||
Altered VH gene segment utilization in the response to phosphorylcholine by aged mice | Q69114845 | ||
Identification of a murine pan-T cell antigen which is also expressed during the terminal phases of B cell differentiation | Q69918537 | ||
B cell precursors are decreased in senescent BALB/c mice, but retain normal mitotic activity in vivo and in vitro | Q70127792 | ||
Stage-specific alterations in murine B lymphopoiesis with age | Q71162999 | ||
Negative selection of multireactive B cell clones in normal adult mice | Q72524379 | ||
Changes in the VH Gene Repertoire of Developing Precursor B Lymphocytes in Mouse Bone Marrow Mediated by the Pre-B Cell Receptor | Q73767616 | ||
The reduced expression of surrogate light chains in B cell precursors from senescent BALB/c mice is associated with decreased E2A proteins | Q74317621 | ||
Increased apoptosis of bone marrow pre-B cells in old mice associated with their low number | Q77457138 | ||
Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice | Q78762514 | ||
Accelerated Notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activation | Q79880417 | ||
Censoring of autoreactive B cell development by the pre-B cell receptor | Q81485516 | ||
B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging | Q83179102 | ||
Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age | Q83888056 | ||
Chronic B Cell Deficiency from Birth Prevents Age-Related Alterations in the B Lineage | Q84652927 | ||
P433 | issue | 3 | |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 382-390 | |
P577 | publication date | 2015-02-27 | |
P1433 | published in | Aging Cell | Q2221073 |
P1476 | title | In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells | |
P478 | volume | 14 |
Q48348426 | Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation |
Q64094881 | B Cell Dysfunction Associated With Aging and Autoimmune Diseases |
Q58763780 | Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells |
Q40439971 | In old BALB/c mice, bone marrow pre-B cell and surrogate light chain reduction is associated with increased B cell reactivity to phosphorylcholine, but reduced T15 idiotype dominance |
Q50166054 | Inflammatory immune cells may impair the PreBCR checkpoint, reduce new B cell production, and Alter the antibody repertoire in old age. |
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