A molecular mechanism for TNF-α-mediated downregulation of B cell responses

scientific article published on 23 November 2011

A molecular mechanism for TNF-α-mediated downregulation of B cell responses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1003964
P932PMC publication ID3700394
P698PubMed publication ID22116831

P2093author name stringAlain Diaz
Ana Marie Landin
Bonnie B Blomberg
Daniela Frasca
Maria Romero
Richard L Riley
Michelle Ratliff
Sarah Alter-Wolf
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Targeting TNF for Treatment of Cancer and AutoimmunityQ37598563
Therapeutic agents for patients with rheumatoid arthritis and an inadequate response to tumour necrosis factor-alpha antagonistsQ37633537
Effector and regulatory B cells: modulators of CD4+ T cell immunityQ37708012
Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway.Q39453060
Differential effects of Francisella tularensis lipopolysaccharide on B lymphocytesQ40106796
Differential regulation of ARE-mediated TNFalpha and IL-1beta mRNA stability by lipopolysaccharide in RAW264.7 cellsQ40270492
Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosisQ44633425
Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminaseQ44756999
Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnoverQ44968876
B cells are required for generation of protective effector and memory CD4 cells in response to Pneumocystis lung infection.Q51982838
Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire.Q52012960
Distinct categories of immunologic changes in frail elderly.Q52026512
Senescent BALB/c mice exhibit decreased expression of lambda5 surrogate light chains and reduced development within the pre-B cell compartment.Q52182767
The immune risk phenotype is associated with IL-6 in the terminal decline stage: Findings from the Swedish NONA immune longitudinal study of very late life functioningQ56986821
Tumour necrosis factor and cancerQ61819217
Age-associated differences in TNF-alpha and nitric oxide production in endotoxic miceQ70916545
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stabilityQ73520889
Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderlyQ77769291
Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expressionQ79317442
Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNAQ80582203
The origins of age-related proinflammatory stateQ81079607
Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathwayQ81194599
B cells amplify IFN-gamma production by T cells via a TNF-alpha-mediated mechanismQ81317325
RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged miceQ81447061
Anti-TNF therapy, from rationale to standard of care: what lessons has it taught us?Q84522489
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)279-286
P577publication date2011-11-23
P1433published inJournal of ImmunologyQ3521441
P1476titleA molecular mechanism for TNF-α-mediated downregulation of B cell responses
P478volume188

Reverse relations

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