Systemic inflammation and disease progression in Alzheimer disease

scientific article

Systemic inflammation and disease progression in Alzheimer disease is …
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scholarly articleQ13442814

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P356DOI10.1212/WNL.0B013E3181B6BB95
P932PMC publication ID2848584
P698PubMed publication ID19738171

P2093author name stringC Holmes
C Dean
V H Perry
C Cunningham
D Culliford
E Zotova
S Kerr
J Woolford
P2860cites workMarkers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart AssociationQ22241929
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Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease.Q35474257
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Systemic infections and inflammation affect chronic neurodegenerationQ36707203
Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's diseaseQ36741828
Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: an epidemiological perspectiveQ36776169
Interleukin-6 covaries inversely with hippocampal grey matter volume in middle-aged adultsQ36925067
Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative diseaseQ37078772
Alzheimer's disease and peripheral infections: the possible contribution from periodontal infections, model and hypothesisQ37167113
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Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.Q48741510
Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis.Q51039637
Plasma cytokines profile in older subjects with late onset Alzheimer's disease or vascular dementia.Q51919320
Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease.Q51945012
A new rating scale for Alzheimer's disease.Q53197509
Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms.Q53218426
Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?Q53233114
Systemic immune aberrations in Alzheimer's disease patients.Q53290628
Re: Inflammatory markers and the risk of Alzheimer disease: the Framingham Study.Q53293404
Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer's disease.Q53392297
Vascular risk factors and Alzheimer's diseaseQ81217736
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
systemic inflammationQ7663815
P304page(s)768-774
P577publication date2009-09-01
P1433published inNeurologyQ1161692
P1476titleSystemic inflammation and disease progression in Alzheimer disease
P478volume73

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Q26799870Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease
Q41762801Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology
Q60046944Rusty Microglia: Trainers of Innate Immunity in Alzheimer's Disease
Q88983835Salivary biomarkers for the diagnosis and monitoring of neurological diseases
Q53347422Selective acetyl- and butyrylcholinesterase inhibitors reduce amyloid-β ex vivo activation of peripheral chemo-cytokines from Alzheimer's disease subjects: exploring the cholinergic anti-inflammatory pathway.
Q39421902Senescent B cells in aging and age-related diseases: Their role in the regulation of antibody responses
Q37015867Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease
Q39901740Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD).
Q90331098Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer's disease
Q57143986Sexual dimorphism in predisposition to Alzheimer's disease
Q26784170Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer's Disease: Impacts on Cognitive Decline
Q47335457Similarity and Differences in Inflammation-Related Characteristics of the Peripheral Immune System of Patients with Parkinson's and Alzheimer's Diseases
Q37249172Sirtuin deacetylases as therapeutic targets in the nervous system
Q59795046Soluble Fibrinogen Triggers Non-cell Autonomous ER Stress-Mediated Microglial-Induced Neurotoxicity
Q93167790Study protocol: ASCRIBED: the impact of Acute SystematiC inflammation upon cerebRospinal fluId and blood BiomarkErs of brain inflammation and injury in dementia: a study in acute hip fracture patients
Q57816573Systemic Inflammation Is Associated With Longitudinal Changes in Cognitive Performance Among Urban Adults
Q47642585Systemic Inflammation and Multimodal Biomarkers in Amnestic Mild Cognitive Impairment and Alzheimer's Disease.
Q37524082Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration
Q37954456Systemic and central immunity in Alzheimer's disease: therapeutic implications
Q35906528Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegeneration
Q58760287Systemic infection modifies the neuroinflammatory response in late stage Alzheimer's disease
Q53320962Systemic inflammation and Alzheimer's disease.
Q92060690Systemic inflammation and causal risk for Alzheimer's dementia: Possibilities and limitations of a Mendelian randomization approach
Q37905132Systemic inflammation and delirium: important co-factors in the progression of dementia.
Q34463760Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration
Q40482561Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium.
Q51736517Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophy.
Q48761733Systemic inflammation induces axon injury during brain inflammation.
Q90559093T cells in Alzheimer's disease: space invaders
Q26823723TDP-43: a new player on the AD field?
Q41694180TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics
Q48029728TREM2 expression in the human brain: a marker of monocyte recruitment?
Q47188911Targeting Neuroinflammation to Treat Alzheimer's Disease.
Q26744219Targeting innate immunity for neurodegenerative disorders of the central nervous system
Q28078474Targeting neuroinflammation in Alzheimer's disease
Q38366835The Antiinflammatory Properties of Humic Substances: A Mini Review
Q45931909The Cholinergic System Modulates Memory and Hippocampal Plasticity via Its Interactions with Non-Neuronal Cells.
Q39324087The IL-1β phenomena in neuroinflammatory diseases
Q50669014The Independent Role of Inflammation in Physical Frailty among Older Adults with Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease.
Q55130777The Inflammatory Nature of Post-surgical Delirium Predicts Benefit of Agents With Anti-TNF Effects, Such as Dexmedetomidine.
Q38671719The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.
Q64105293The Modulatory Effect of Gender and Cytomegalovirus-Seropositivity on Circulating Inflammatory Factors and Cognitive Performance in Elderly Individuals
Q90599917The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration
Q55294882The Role of Immunosenescence in Neurodegenerative Diseases.
Q33737263The Role of Interleukin-18, Oxidative Stress and Metabolic Syndrome in Alzheimer's Disease
Q39424451The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity
Q46141259The Role of Nitric Oxide from Neurological Disease to Cancer
Q26753199The blood-brain barrier in systemic inflammation
Q34993643The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1
Q40465097The effect of systemic inflammation on human brain barrier function
Q90098412The endotoxin hypothesis of neurodegeneration
Q35064995The evolving biology of microglia in Alzheimer's disease.
Q37830018The human microbiome in multiple sclerosis: pathogenic or protective constituents?
Q35860997The immunology of neurodegeneration
Q34562975The impact of age-related dysregulation of the angiotensin system on mitochondrial redox balance
Q38123243The impact of neuroimmune changes on development of amyloid pathology; relevance to Alzheimer's disease.
Q38609436The importance of postoperative quality of recovery: influences, assessment, and clinical and prognostic implications
Q50102950The influence of TNF inhibitors on dementia incidence in patients with rheumatoid arthritis; an analysis from the BSRBR-RA.
Q38156518The influence of cannabinoids on generic traits of neurodegeneration
Q92493391The intestinal microbiome and Alzheimer's disease: A review
Q92518346The neuro-glial coagulonome: the thrombin receptor and coagulation pathways as major players in neurological diseases
Q37091521The relationship between Helicobacter pylori infection and Alzheimer's disease in Japan.
Q38105903The role of inflammation in sporadic and familial Parkinson's disease
Q37765627The role of inflammation in the pathogenesis of delirium and dementia in older adults: a review.
Q42932695The role of tumor necrosis factor-alpha in cognitive improvement after peroxisome proliferator-activator receptor gamma agonist pioglitazone treatment in Alzheimer's disease
Q64990947The troubling story of blood-driven dementias.
Q64067670Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System
Q37678539Therapeutic implications of the prostaglandin pathway in Alzheimer's disease
Q35698522Therapeutic potential of mGluR5 targeting in Alzheimer's disease
Q40302712Tooth Loss and Risk of Dementia in the Community: the Hisayama Study
Q30543926Transcriptomics of cortical gray matter thickness decline during normal aging
Q37839130Treating inflammation in childhood neurodegenerative disorders
Q38607117Treating the whole body in Huntington's disease
Q39547833Treatment for Rheumatoid Arthritis and Risk of Alzheimer's Disease: A Nested Case-Control Analysis
Q92603575Tumor Necrosis Factor-Alpha Alters Electrophysiological Properties of Rabbit Hippocampal Neurons
Q35031990Tumour necrosis factor-α (TNF-α) and miRNA expression in frontal and temporal neocortex in Alzheimer's disease and the effect of TNF-α on miRNA expression in vitro
Q91646701Understanding the Physiological Links Between Physical Frailty and Cognitive Decline
Q37985635Viral and inflammatory triggers of neurodegenerative diseases
Q39328741Volunteering Is Associated with Lower Risk of Cognitive Impairment
Q42026475Whether, when and how chronic inflammation increases the risk of developing late-onset Alzheimer's disease
Q38759253YKL-40 as a Potential Biomarker and a Possible Target in Therapeutic Strategies of Alzheimer's Disease

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