| scholarly article | Q13442814 |
| P50 | author | Donal J Cox | Q86612047 |
| Andrew G Bowie | Q38323725 | ||
| Colm Cunningham | Q48462688 | ||
| Aisling Dunne | Q60020573 | ||
| P2093 | author name string | Marcin Baran | |
| David G Williams | |||
| Robert H Field | |||
| P2860 | cites work | IFI16 is an innate immune sensor for intracellular DNA | Q24301720 |
| IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection | Q24302985 | ||
| Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway | Q24306635 | ||
| RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate | Q24315639 | ||
| RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway | Q24317317 | ||
| AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC | Q24319706 | ||
| AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA | Q24319765 | ||
| An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome | Q24319799 | ||
| Viruses and neurodegeneration | Q26991740 | ||
| Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA | Q28118718 | ||
| The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses | Q28391800 | ||
| HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA | Q28585347 | ||
| The mammalian PYHIN gene family: phylogeny, evolution and expression | Q28727434 | ||
| Microglial cells in astroglial cultures: a cautionary note | Q30480840 | ||
| A protective role for ELR+ chemokines during acute viral encephalomyelitis | Q33515263 | ||
| Circulating nucleic acid analysis: diagnostic applications for acute pathologies | Q82493002 | ||
| The value of serial plasma nuclear and mitochondrial DNA levels in patients with acute ischemic stroke | Q82734214 | ||
| Systemic inflammation and disease progression in Alzheimer disease | Q33765718 | ||
| Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity | Q33830730 | ||
| Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells | Q33934056 | ||
| Cytosolic DNA sensors regulating type I interferon induction. | Q34028147 | ||
| Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study | Q34144095 | ||
| RIG-I mediates nonsegmented negative-sense RNA virus-induced inflammatory immune responses of primary human astrocytes | Q34158564 | ||
| Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects | Q34367481 | ||
| CC chemokine ligand 3 (CCL3) regulates CD8(+)-T-cell effector function and migration following viral infection. | Q34781528 | ||
| Activation of interferon signaling pathways in spinal cord astrocytes from an ALS mouse model | Q34798823 | ||
| Astrogliosis involves activation of retinoic acid-inducible gene-like signaling in the innate immune response after spinal cord injury | Q35693270 | ||
| Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegeneration | Q35906528 | ||
| Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis | Q36673928 | ||
| Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease | Q37078772 | ||
| Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5 | Q37139807 | ||
| Characterization of retinoic acid-inducible gene-I expression in primary murine glia following exposure to vesicular stomatitis virus | Q37322441 | ||
| Blood cell-derived RANTES mediates cerebral microvascular dysfunction, inflammation, and tissue injury after focal ischemia-reperfusion | Q37357137 | ||
| Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration | Q37583628 | ||
| Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. | Q37627775 | ||
| Pyroptotic neuronal cell death mediated by the AIM2 inflammasome. | Q37695313 | ||
| The PYHIN protein family as mediators of host defenses. | Q37925069 | ||
| The interferon response to intracellular DNA: why so many receptors? | Q38130353 | ||
| Innate antiviral signalling in the central nervous system | Q38169444 | ||
| Innate immune activation in neurodegenerative disease | Q38223011 | ||
| Chronic systemic infection exacerbates ischemic brain damage via a CCL5 (regulated on activation, normal T-cell expressed and secreted)-mediated proinflammatory response in mice | Q42543196 | ||
| Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response. | Q45098944 | ||
| Neuropathologically distinct prion strains give rise to similar temporal profiles of behavioral deficits | Q45248355 | ||
| Toll-like receptor 3 activation modulates hippocampal network excitability, via glial production of interferon-β. | Q48098109 | ||
| The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells | Q48143296 | ||
| Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system | Q48159292 | ||
| The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C). | Q48262209 | ||
| Interleukin-6 levels are increased in temporal lobe epilepsy but not in extra-temporal lobe epilepsy. | Q48719793 | ||
| The concentration of cell-free DNA in focal epilepsy. | Q51070879 | ||
| P433 | issue | 5 | |
| P921 | main subject | astrocyte | Q502961 |
| microglia | Q1622829 | ||
| neurodegeneration | Q1755122 | ||
| P304 | page(s) | 812-825 | |
| P577 | publication date | 2015-01-27 | |
| P1433 | published in | Glia | Q15716658 |
| P1476 | title | DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease | |
| P478 | volume | 63 |
| Q93205779 | Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity |
| Q91215987 | Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression |
| Q36444585 | CpG methylation differences between neurons and glia are highly conserved from mouse to human |
| Q47559126 | Deciphering sex differences in the immune system and depression. |
| Q37084675 | Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype |
| Q58752961 | Effect of chemokine CC ligand 2 (CCL2) on α‑synuclein‑induced microglia proliferation and neuronal apoptosis |
| Q38922258 | Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension-related sympathoexcitation |
| Q64082958 | Expression and localization of absent in melanoma 2 in the injured spinal cord |
| Q38638589 | Human microglia and astrocytes express cGAS-STING viral sensing components |
| Q89581609 | Interferon-β Plays a Detrimental Role in Experimental Traumatic Brain Injury by Enhancing Neuroinflammation That Drives Chronic Neurodegeneration |
| Q55003404 | LncRNA MALAT1 promotes high glucose-induced inflammatory response of microglial cells via provoking MyD88/IRAK1/TRAF6 signaling. |
| Q40580578 | Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity. |
| Q90437575 | PERK-STING Signaling Drives Neuroinflammation in Traumatic Brain Injury |
| Q42712047 | Pharmacological Tools to Activate Microglia and their Possible use to Study Neural Network Patho-physiology. |
| Q39105980 | Sterile Neuroinflammation and Strategies for Therapeutic Intervention |
| Q97518828 | The World Goes Bats: Living Longer and Tolerating Viruses |
| Q92447559 | The role of microglia in ischemic preconditioning |
| Q39609930 | Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease. |
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