The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration

scientific article published on 24 January 2018

The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4172/2161-0460.1000421
P932PMC publication ID6293973
P698PubMed publication ID30560011

P50authorAnn Marie SchmidtQ89261684
Judyta JuranekQ56907008
P2093author name stringMichael MacLean
Julia Derk
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The Astrocytic S100B Protein with Its Receptor RAGE Is Aberrantly Expressed in SOD1G93A Models, and Its Inhibition Decreases the Expression of Proinflammatory GenesQ33868126
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Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.Q34046424
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CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Q34254575
Receptor for advanced glycation end products binds to phosphatidylserine and assists in the clearance of apoptotic cellsQ34797370
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RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in DiabetesQ35740332
Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal TransductionQ35943768
Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways.Q36054820
The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In VitroQ36166108
Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.Q36185908
S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathwayQ36411027
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Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signalingQ36478250
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RAGE and modulation of ischemic injury in the diabetic myocardiumQ36756482
The microglial sensome revealed by direct RNA sequencingQ37341692
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Targeted inhibition of RAGE in substantia nigra of rats blocks 6-OHDA-induced dopaminergic denervationQ39018573
RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's diseaseQ39638245
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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic miceQ40251711
Regulation of human mononuclear phagocyte migration by cell surface-binding proteins for advanced glycation end productsQ40304611
Regulation of monocyte migration by amphoterin (HMGB1).Q40558415
Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous systemQ40668935
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune responseQ40899986
Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation.Q40975198
Microglia, scavenger receptors, and the pathogenesis of Alzheimer's diseaseQ41751577
Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral Sclerosis.Q41871282
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.Q42186976
Association study of Parkin gene polymorphisms with idiopathic Parkinson diseaseQ42604036
Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicityQ43090705
RAGE and arthritis: the G82S polymorphism amplifies the inflammatory responseQ44032299
Detection of N epsilon-(carboxymethyl)lysine (CML) and non-CML advanced glycation end-products in the anterior horn of amyotrophic lateral sclerosis spinal cordQ44127793
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brainQ44479225
The advanced glycation end-product N epsilon-(carboxymethyl)lysine level is elevated in cerebrospinal fluid of patients with amyotrophic lateral sclerosisQ45133669
Genetic Association of HLA Gene Variants with MRI Brain Structure in Alzheimer's DiseaseQ46113901
beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1.Q46404934
Serum-soluble receptor for advanced glycation end product levels in patients with amyotrophic lateral sclerosisQ46903808
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brainsQ46904404
Fingolimod anti-inflammatory and neuroprotective effects modulation of RAGE axis in multiple sclerosis patientsQ47338812
Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment.Q47414857
Knockdown of Diaph1 expression inhibits migration and decreases the expression of MMP2 and MMP9 in human glioma cellsQ47647991
beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.Q48009625
Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress.Q50180621
Soluble receptor for advanced glycation end products in multiple sclerosis: a potential marker of disease severity.Q51700919
S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis.Q52151935
Receptor for advanced glycation end-products (RAGE) activates divergent signaling pathways to augment neurite outgrowth of adult sensory neurons.Q53090487
High-mobility group box 1 in multiple sclerosis.Q53210919
Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS.Q53272106
Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.Q53348339
A functional p.82G>S polymorphism in the RAGE gene is associated with multiple sclerosis in the Chinese population.Q54376586
Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis.Q54523448
Distribution and cellular localization of high mobility group box protein 1 (HMGB1) in the spinal cord of a transgenic mouse model of ALSQ57716389
Amyotrophic lateral sclerosisQ59544266
RAGE Gene Polymorphisms in Patients with Multiple SclerosisQ60732952
P433issue1
P921main subjectneurodegenerationQ1755122
P577publication date2018-01-24
P1433published inJournal of Alzheimer's disease & ParkinsonismQ27724348
P1476titleThe Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration
P478volume8

Reverse relations

cites work (P2860)
Q64944576Soluble Forms of the Receptor for Advanced Glycation Endproducts (RAGE) in Periodontitis.
Q64236740Thrombin and the in Neurotrauma, ALS, and Other Neurodegenerative Disorders

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