| P2093 | author name string | Ahmed Lasfar | |
| | Karine A Cohen-Solal | |
| P2860 | cites work | TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4 | Q24314661 |
| | Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways | Q24317164 |
| | A new fork for clinical application: targeting forkhead transcription factors in cancer | Q24651455 |
| | Mitf regulation of Dia1 controls melanoma proliferation and invasiveness | Q24672631 |
| | Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation | Q24675569 |
| | Rewired ERK-JNK signaling pathways in melanoma | Q24683737 |
| | Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation | Q28117650 |
| | Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: consequences for proliferation, survival, and metastasis | Q28177586 |
| | Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: functional implications for transforming growth factor beta signaling | Q28207048 |
| | Characterization of Sno expression in malignant melanoma | Q28243538 |
| | Melanoma-inhibiting activity, a novel serum marker for progression of malignant melanoma | Q28245095 |
| | TGFbeta in Cancer | Q28288866 |
| | Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF | Q28298995 |
| | Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis | Q28301271 |
| | In situ analysis of transforming growth factor-beta s (TGF-beta 1, TGF-beta 2, TGF-beta 3), and TGF-beta type II receptor expression in malignant melanoma. | Q53462875 |
| | Mitogen-actived protein kinase activation is an early event in melanoma progression. | Q53745580 |
| | Transforming growth factor-beta1 increases survival of human melanoma through stroma remodeling. | Q53987287 |
| | Amplification of CDK4 and MDM2 in malignant melanoma. | Q54622216 |
| | Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis. | Q54684094 |
| | Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis | Q54976432 |
| | Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling | Q58450931 |
| | Expression of the c-ski proto-oncogene in human melanoma cell lines | Q70656827 |
| | Desensitization of melanoma cells to autocrine TGF-beta isoforms | Q74523228 |
| | N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin | Q77519474 |
| | Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype | Q78202943 |
| | Screening of N-ras codon 61 mutations in paired primary and metastatic cutaneous melanomas: mutations occur early and persist throughout tumor progression | Q78508829 |
| | SKI is critical for repressing the growth inhibitory function of TGF-beta in human melanoma | Q81355194 |
| | Inhibition of PAX3 by TGF-beta modulates melanocyte viability | Q82695474 |
| | SKI knockdown inhibits human melanoma tumor growth in vivo | Q84759300 |
| | Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases | Q28345479 |
| | Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor | Q28509336 |
| | Reversible Smad-dependent signaling between tumor suppression and oncogenesis | Q28564212 |
| | Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling | Q28631440 |
| | Cell cycle and death control: long live Forkheads | Q28646130 |
| | Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma | Q29614282 |
| | Distinct sets of genetic alterations in melanoma | Q29614965 |
| | Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer | Q29616379 |
| | Melanoma inhibitory activity (MIA): an important molecule in melanoma development and progression. | Q30351793 |
| | Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination | Q30491014 |
| | Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition | Q33411645 |
| | FOXOs, cancer and regulation of apoptosis | Q33642512 |
| | Genetics of melanoma predisposition | Q34203435 |
| | Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor | Q34302649 |
| | Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas | Q34405159 |
| | Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways. | Q34579319 |
| | The role of chemokines in melanoma tumor growth and metastasis | Q34680888 |
| | In vivo switching of human melanoma cells between proliferative and invasive states | Q34745037 |
| | Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects | Q34792580 |
| | The PTEN-PI3K pathway: of feedbacks and cross-talks | Q34828662 |
| | Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling | Q35013177 |
| | A FoxO-Smad synexpression group in human keratinocytes | Q35036428 |
| | A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras | Q35193411 |
| | Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim | Q35320797 |
| | Transcription factors involved in development and progression of malignant melanoma. | Q35619048 |
| | Melanoma-associated expression of transforming growth factor-beta isoforms | Q35773976 |
| | Expression of transforming growth factor-beta 2 in malignant melanoma correlates with the depth of tumor invasion. Implications for tumor progression | Q35833728 |
| | Rb/E2F: a two-edged sword in the melanocytic system | Q36178390 |
| | The WNT/Beta-catenin pathway in melanoma | Q36251062 |
| | Smad3 phosphorylation by cyclin-dependent kinases | Q36313453 |
| | Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer. | Q36564164 |
| | N-ras mutations in human cutaneous melanoma from sun-exposed body sites. | Q36770363 |
| | PI3K/PTEN signaling in tumorigenesis and angiogenesis | Q36982971 |
| | Understanding signaling cascades in melanoma | Q37034487 |
| | How to make a melanoma: what do we know of the primary clonal events? | Q37114124 |
| | Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas | Q37118264 |
| | Transforming growth factor-beta in cutaneous melanoma | Q37143532 |
| | Melanoma and the tumor microenvironment | Q37244724 |
| | A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204. | Q37338950 |
| | Ski and SnoN, potent negative regulators of TGF-beta signaling | Q37359949 |
| | Genetic risk factors for melanoma | Q37544403 |
| | Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling | Q38308653 |
| | Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1. | Q38319170 |
| | Non-malignant and tumor-derived cells differ in their requirement for p27Kip1 in transforming growth factor-beta-mediated G1 arrest | Q38363471 |
| | The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells. | Q39820039 |
| | Id2 suppression of p15 counters TGF-beta-mediated growth inhibition of melanoma cells | Q39860820 |
| | Transforming growth factor-{beta}-inducible phosphorylation of Smad3 | Q39883712 |
| | C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells | Q39954044 |
| | mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation | Q39969679 |
| | Involvement of FKHRL1 in melanoma cell survival and death. | Q39989951 |
| | Adenovirus-mediated gene transfer of FKHRL1 triple mutant efficiently induces apoptosis in melanoma cells. | Q40252297 |
| | Influence of melanoma inhibitory activity on transforming growth factor-beta signaling in malignant melanoma. | Q40255145 |
| | RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells | Q40337065 |
| | Anatomic site-specific patterns of gene copy number gains in skin, mucosal, and uveal melanomas detected by fluorescence in situ hybridization | Q40344910 |
| | Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3. | Q40374801 |
| | Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo | Q40399612 |
| | Selective induction of interleukin-8 expression in metastatic melanoma cells by transforming growth factor-beta 1. | Q40405515 |
| | Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo | Q40497387 |
| | TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions | Q40522842 |
| | Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells | Q40610753 |
| | Filamin associates with Smads and regulates transforming growth factor-beta signaling | Q40817232 |
| | Expression of activated N-ras in a primary melanoma cell line counteracts growth inhibition by transforming growth factor-beta. | Q40875219 |
| | TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling | Q41083690 |
| | TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: evidence for cooperation between p21Cip1/WAF1 and p27Kip1. | Q41145870 |
| | Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells | Q41494312 |
| | Cellular senescence in naevi and immortalisation in melanoma: a role for p16? | Q42016240 |
| | Key roles for transforming growth factor beta in melanocyte stem cell maintenance | Q42324335 |
| | Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature | Q42804978 |
| | Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays. | Q42806564 |
| | Elevated plasma levels of transforming growth factor (TGF)-beta1 and TGF-beta2 in patients with disseminated malignant melanoma | Q42858939 |
| | FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons | Q42918105 |
| | Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells | Q42999573 |
| | Cyclin D1 is a candidate oncogene in cutaneous melanoma | Q44010457 |
| | Overexpression of cyclin D1 inhibits TNF-induced growth arrest | Q44450345 |
| | Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma | Q45402508 |
| | Cyclin-dependent kinases regulate the antiproliferative function of Smads | Q47229633 |
| | Malignant melanoma with monster cells showing massive cyclin D1 amplification | Q47747284 |
| | Clinical significance of the expression of c-Ski and SnoN, possible mediators in TGF-beta resistance, in primary cutaneous melanoma | Q49157540 |
| | Exposure of normal human melanocytes to a tumor promoting phorbol ester reverses growth suppression by transforming growth factor beta. | Q50950984 |
| | Independent regulation of growth and SMAD-mediated transcription by transforming growth factor beta in human melanoma cells. | Q52533841 |
| | Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation. | Q53321709 |
| | Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer. | Q53389037 |
| | Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma. | Q53391786 |
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1710-1717 | |
| P577 | publication date | 2010-07-23 | |
| P1433 | published in | Carcinogenesis | Q326022 |
| P1476 | title | Resistance to transforming growth factor β-mediated tumor suppression in melanoma: are multiple mechanisms in place? | |
| P478 | volume | 31 | |