| scholarly article | Q13442814 |
| P2093 | author name string | Fang Liu | |
| Guannan Wang | |||
| Isao Matsuura | |||
| Dongming He | |||
| P2860 | cites work | Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal | Q24301688 |
| The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation | Q24309341 | ||
| MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling | Q24310282 | ||
| Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes | Q24310852 | ||
| MADR1, a MAD-related protein that functions in BMP2 signaling pathways | Q24317247 | ||
| Receptor-associated Mad homologues synergize as effectors of the TGF-beta response | Q24318330 | ||
| The Smad3 linker region contains a transcriptional activation domain | Q24320175 | ||
| The protein kinase complement of the human genome | Q24324497 | ||
| Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II | Q24551154 | ||
| Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling | Q24685123 | ||
| Characterization of a novel transcriptionally active domain in the transforming growth factor beta-regulated Smad3 protein | Q24815288 | ||
| Mechanisms of TGF-beta signaling from cell membrane to the nucleus | Q27860785 | ||
| TGF-beta signalling from cell membrane to nucleus through SMAD proteins | Q28131770 | ||
| Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation | Q28140761 | ||
| TGFbeta signaling in growth control, cancer, and heritable disorders | Q28142605 | ||
| Smad-dependent and Smad-independent pathways in TGF-beta family signalling | Q28208250 | ||
| Cdk2 knockout mice are viable | Q28210245 | ||
| Smad4 and FAST-1 in the assembly of activin-responsive factor | Q28248490 | ||
| Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1 | Q28251731 | ||
| New insights into TGF-beta-Smad signalling | Q28260517 | ||
| Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6 | Q28277471 | ||
| Cyclin-dependent kinases regulate the antiproliferative function of Smads | Q47229633 | ||
| Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice | Q48823384 | ||
| Mouse development and cell proliferation in the absence of D-cyclins. | Q52088064 | ||
| Evidence for antagonism of BMP-4 signals by MAP kinase during Xenopus axis determination and neural specification. | Q52551781 | ||
| A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance. | Q53596084 | ||
| Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis. | Q54684094 | ||
| Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker | Q60325056 | ||
| The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta | Q73236678 | ||
| Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription | Q73280041 | ||
| Integration of Smad and MAPK pathways: a link and a linker revisited | Q75216840 | ||
| Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGFbeta | Q77340279 | ||
| An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts | Q77450058 | ||
| In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis | Q28508517 | ||
| Cyclin E ablation in the mouse | Q28593960 | ||
| The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase | Q28628494 | ||
| Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling | Q28631440 | ||
| Specificity and versatility in tgf-beta signaling through Smads | Q29616324 | ||
| Properties and potential-applications of chemical inhibitors of cyclin-dependent kinases | Q33716146 | ||
| Role of Ras and Mapks in TGFbeta signaling | Q33857574 | ||
| Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo | Q34082542 | ||
| TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses | Q34089674 | ||
| GSK3 takes centre stage more than 20 years after its discovery | Q34374129 | ||
| Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta | Q35157728 | ||
| A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras | Q35193411 | ||
| Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases | Q35201617 | ||
| Receptor-regulated Smads in TGF-beta signaling | Q35212942 | ||
| Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. | Q35875804 | ||
| Dorsal-ventral patterning and neural induction in Xenopus embryos | Q35912796 | ||
| Living with or without cyclins and cyclin-dependent kinases | Q35951291 | ||
| Inhibition of Smad antiproliferative function by CDK phosphorylation | Q35990233 | ||
| Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis. | Q36241249 | ||
| Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells | Q36246072 | ||
| Inhibitors of cyclin-dependent kinase modulators for cancer therapy. | Q36304595 | ||
| Smad3 phosphorylation by cyclin-dependent kinases | Q36313453 | ||
| Protein kinase inhibitors. | Q36658277 | ||
| Integrating positional information at the level of Smad1/5/8. | Q37203477 | ||
| Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase. | Q37672900 | ||
| Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction | Q39445051 | ||
| Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3. | Q40374801 | ||
| Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction | Q40385522 | ||
| Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells | Q40444996 | ||
| Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo | Q40497387 | ||
| TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions | Q40522842 | ||
| Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase | Q40709028 | ||
| Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation | Q40793124 | ||
| TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling | Q41083690 | ||
| Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells | Q41357904 | ||
| Cdk1 is sufficient to drive the mammalian cell cycle | Q41791627 | ||
| Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275. | Q42283108 | ||
| Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation | Q42480580 | ||
| Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. | Q42555777 | ||
| Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? | Q43507724 | ||
| Nuclear exclusion of Smad2 is a mechanism leading to loss of competence | Q44030633 | ||
| p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts | Q44598575 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 9663-9673 | |
| P577 | publication date | 2009-02-13 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Transforming growth factor-{beta}-inducible phosphorylation of Smad3 | |
| P478 | volume | 284 |
| Q27670475 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code |
| Q34067264 | Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. |
| Q24295158 | Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3 |
| Q39906208 | Anticytokine therapy for osteoarthritis: evidence to date |
| Q34701194 | Bone morphogenetic protein 4 promotes mammalian oogonial stem cell differentiation via Smad1/5/8 signaling |
| Q42859300 | Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart |
| Q37924871 | Cell biology of Smad2/3 linker region phosphorylation in vascular smooth muscle |
| Q47161268 | Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis |
| Q35025142 | Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-β-mediated growth inhibition. |
| Q37679939 | DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis |
| Q38958008 | Definition of smad3 phosphorylation events that affect malignant and metastatic behaviors in breast cancer cells |
| Q38790780 | Deregulated E2F5/p38/SMAD3 Circuitry Reinforces the Pro-Tumorigenic Switch of TGFβ Signaling in Prostate Cancer |
| Q37998023 | Differential Regulation of TGF-β/Smad Signaling in Hepatic Stellate Cells between Acute and Chronic Liver Injuries |
| Q36030083 | Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells |
| Q38740937 | Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β |
| Q35082779 | Endothelial dysfunction exacerbates renal interstitial fibrosis through enhancing fibroblast Smad3 linker phosphorylation in the mouse obstructed kidney. |
| Q54990315 | Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis. |
| Q30370588 | Epidermal growth factor inhibits transforming growth factor-β-induced fibrogenic differentiation marker expression through ERK activation. |
| Q89118320 | Fibroblast Growth Factor 2 as an Antifibrotic: Antagonism of Myofibroblast Differentiation and Suppression of Pro-Fibrotic Gene Expression |
| Q39752535 | Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-beta-mediated cancer cell invasiveness |
| Q37710008 | Heat shock transcription factor 1 protects against pressure overload-induced cardiac fibrosis via Smad3. |
| Q52328455 | Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation. |
| Q92911727 | Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway |
| Q93089254 | Insulin-like growth factor binding protein-4 exerts antifibrotic activity by reducing levels of connective tissue growth factor and the C-X-C chemokine receptor 4 |
| Q35583053 | Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium |
| Q47449827 | Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition |
| Q52935358 | Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4+ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling. |
| Q36583453 | Mechanical stretching stimulates collagen synthesis via down-regulating SO2/AAT1 pathway |
| Q41448906 | MicroRNA-195 Activates Hepatic Stellate Cells In Vitro by Targeting Smad7. |
| Q34450728 | Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma |
| Q35800181 | Non-degradative ubiquitination in Smad-dependent TGF-β signaling |
| Q100533933 | OSR1 phosphorylates the Smad2/3 linker region and induces TGF-β1 autocrine to promote EMT and metastasis in breast cancer |
| Q28287002 | Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis |
| Q38265843 | Peptidyl-prolyl isomerases: functionality and potential therapeutic targets in cardiovascular disease |
| Q61810971 | Phosphorylation status at Smad3 linker region modulates transforming growth factor-β-induced epithelial-mesenchymal transition and cancer progression |
| Q43915130 | Pin1 plays a critical role as a molecular switch in canonical BMP signaling. |
| Q33581891 | Pin1 promotes transforming growth factor-beta-induced migration and invasion |
| Q38012228 | Post-translational regulation of TGF-β receptor and Smad signaling. |
| Q39026435 | Posttranslational Regulation of Smads |
| Q45834311 | Reactive Oxygen Species and NOX Enzymes Are Emerging as Key Players in Cutaneous Wound Repair |
| Q39134073 | Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules |
| Q26996826 | Regulation of TGF-β Signal Transduction |
| Q33624967 | Regulation of Ubiquitin Enzymes in the TGF-β Pathway. |
| Q37775417 | Resistance to transforming growth factor β-mediated tumor suppression in melanoma: are multiple mechanisms in place? |
| Q51620108 | Rewiring of the apoptotic TGF-β-SMAD/NFκB pathway through an oncogenic function of p27 in human papillary thyroid cancer. |
| Q84759300 | SKI knockdown inhibits human melanoma tumor growth in vivo |
| Q39726558 | SKI promotes Smad3 linker phosphorylations associated with the tumor-promoting trait of TGFbeta |
| Q37509215 | Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific manner |
| Q39005862 | Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways |
| Q36311752 | Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition |
| Q30812886 | Single-Molecule Imaging Reveals the Activation Dynamics of Intracellular Protein Smad3 on Cell Membrane |
| Q37785805 | Smad linker region phosphorylation in the regulation of extracellular matrix synthesis. |
| Q35478946 | Smad phosphoisoform signaling specificity: the right place at the right time |
| Q35649316 | Smad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells |
| Q35159428 | Smad2 and PEA3 cooperatively regulate transcription of response gene to complement 32 in TGF-β-induced smooth muscle cell differentiation of neural crest cells |
| Q44862683 | Smad3 and Smad3 phosphoisoforms are prognostic markers of gastric carcinoma. |
| Q53391030 | Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy. |
| Q39708889 | Src is a major signaling component for CTGF induction by TGF-beta1 in osteoblasts |
| Q41137172 | Suppressor of cytokine signaling 1 is a positive regulator of TGF-β-induced prostaglandin production in human follicular dendritic cell-like cells |
| Q38906099 | TGF-β Signaling from Receptors to Smads |
| Q55260433 | TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation. |
| Q33678064 | TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma |
| Q38165027 | TGF-β signal shifting between tumor suppression and fibro-carcinogenesis in human chronic liver diseases |
| Q36832622 | TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells |
| Q34120419 | TGF-β/Smad signaling during hepatic fibro-carcinogenesis (review). |
| Q26861134 | The GSK-3 family as therapeutic target for myocardial diseases |
| Q40996773 | The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells |
| Q38116934 | The TGFbeta superfamily signaling pathway |
| Q39121230 | The prognostic significance of Smad3, Smad4, Smad3 phosphoisoform expression in esophageal squamous cell carcinoma |
| Q40463304 | Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. |
| Q55070630 | Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells. |
| Q38192972 | Transforming growth factor-beta and its implication in the malignancy of gliomas |
| Q90355553 | Tryptophan metabolites kynurenine and serotonin regulate fibroblast activation and fibrosis |
| Q57120552 | [Tumor necrosis factor-α and transforming growth factor-β1 balance liver stem cell differentiation in cholestatic cirrhosis] |
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