review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Simon J Cook | |
Ceri M Wiggins | |||
Katherine E Ewings | |||
P433 | issue | 18 | |
P304 | page(s) | 2236-2240 | |
P577 | publication date | 2007-07-10 | |
P1433 | published in | Cell Cycle | Q1254166 |
P1476 | title | Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels | |
P478 | volume | 6 |
Q46484915 | A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling. |
Q53126217 | A significant imbalance in mitosis versus apoptosis accelerates the growth rate of sessile serrated adenoma/polyps. |
Q37109803 | Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer |
Q39797784 | Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization |
Q38888011 | Antioxidant and hepatoprotective effect of Penthorum chinense Pursh extract against t-BHP-induced liver damage in L02 cells. |
Q35561961 | Antiproliferative and apoptosis-inducing activity of schisandrin B against human glioma cells |
Q33930057 | Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo |
Q37605160 | Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics |
Q88624173 | BCL-2 levels do not predict azathioprine treatment response in inflammatory bowel disease, but inhibition induces lymphocyte apoptosis and ameliorates colitis in mice |
Q52878050 | BH3-only proteins: possible proapoptotic triggers for melanoma therapy. |
Q39726300 | BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer |
Q46438962 | Balance between apoptosis or survival induced by changes in extracellular-matrix composition in human mesangial cells: a key role for ILK-NFκB pathway |
Q37187224 | Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma |
Q34047415 | Bim nuclear translocation and inactivation by viral interferon regulatory factor |
Q38715353 | Biochemical changes of salivary gland adenoid cystic carcinoma cells induced by SGI-1776. |
Q38822778 | CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway |
Q34206158 | CCL21/CCR7 prevents apoptosis via the ERK pathway in human non-small cell lung cancer cells |
Q51755481 | CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim. |
Q92150562 | Cell Death in the Kidney |
Q39539196 | Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation |
Q28540339 | Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells |
Q41836780 | Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM. |
Q42204382 | Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress |
Q57187140 | Curcumin protects against diabetic cardiomyopathy by promoting autophagy and alleviating apoptosis |
Q33763027 | Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells |
Q37745522 | Cysteine-linked dimerization of BST-2 confers anoikis resistance to breast cancer cells by negating proapoptotic activities to promote tumor cell survival and growth |
Q37655968 | Dicer function is required in the metanephric mesenchyme for early kidney development |
Q38115771 | Distinct roles of Kaposi's sarcoma-associated herpesvirus-encoded viral interferon regulatory factors in inflammatory response and cancer |
Q36586167 | Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use. |
Q41941878 | Expression and function of bcl-2 proteins in melanoma |
Q36823747 | FAT10 protects cardiac myocytes against apoptosis |
Q39718208 | Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis |
Q34299388 | Human herpesvirus 8 interferon regulatory factor-mediated BH3-only protein inhibition via Bid BH3-B mimicry |
Q43759405 | Hypothermia attenuates apoptosis and protects contact between myelin basic protein-expressing oligodendroglial-lineage cells and neurons against hypoxia-ischemia |
Q41344802 | IER3IP1 deficiency leads to increased β-cell death and decreased β-cell proliferation |
Q27304738 | IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling study |
Q39952567 | Immunomodulation of human B cells following treatment with intravenous immunoglobulins involves increased phosphorylation of extracellular signal-regulated kinases 1 and 2. |
Q50998106 | Impaired removal of Vβ8(+) lymphocytes aggravates colitis in mice deficient for B cell lymphoma-2-interacting mediator of cell death (Bim). |
Q50743251 | Increased lymphocyte apoptosis in mouse models of colitis upon ABT-737 treatment is dependent upon BIM expression. |
Q37547526 | Inhibition of Bim enhances replication of varicella-zoster virus and delays plaque formation in virus-infected cells |
Q41951300 | Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. |
Q34153515 | Lipocalin 2 modulates the cellular response to amyloid beta. |
Q36706340 | MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex |
Q37341018 | Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis |
Q39010041 | Melanoma never says die. |
Q39222725 | Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells |
Q37691434 | MicroRNA-29c-5p suppresses gallbladder carcinoma progression by directly targeting CPEB4 and inhibiting the MAPK pathway |
Q64230493 | Model-Based Assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-Cell Immune Responses |
Q39749582 | Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78. |
Q34233598 | Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK). |
Q36096963 | Nec-1 enhances shikonin-induced apoptosis in leukemia cells by inhibition of RIP-1 and ERK1/2 |
Q37028555 | Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival |
Q35127404 | Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway |
Q39207391 | Oridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer cells. |
Q36004222 | Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice |
Q34663501 | PED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1 |
Q38881938 | Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability |
Q39704679 | PectaSol-C modified citrus pectin induces apoptosis and inhibition of proliferation in human and mouse androgen-dependent and- independent prostate cancer cells |
Q36163639 | Perforin plays an unexpected role in regulating T-cell contraction during prolonged Listeria monocytogenes infection. |
Q39687146 | ProstaCaid induces G2/M cell cycle arrest and apoptosis in human and mouse androgen-dependent and-independent prostate cancer cells |
Q41006403 | Pseudorabies virus glycoprotein gE triggers ERK1/2 phosphorylation and degradation of the pro-apoptotic protein Bim in epithelial cells |
Q26781203 | Regulation of Bim in Health and Disease |
Q45957396 | Relative resistance of SGK1 knockout mice against chemical carcinogenesis. |
Q33825096 | Role for the proapoptotic factor BIM in mediating imatinib-induced apoptosis in a c-KIT-dependent gastrointestinal stromal tumor cell line |
Q37331465 | Role of apoptosis in colon cancer biology, therapy, and prevention |
Q38120523 | Role of the Crosstalk between Autophagy and Apoptosis in Cancer |
Q33800318 | Roles of the NF-kappaB pathway in lymphocyte development and function |
Q37339049 | Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells |
Q92093081 | SOX7 regulates MAPK/ERK-BIM mediated apoptosis in cancer cells |
Q36083385 | STAT3 mediates resistance to MEK inhibitor through microRNA miR-17. |
Q34104084 | Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells. |
Q30437150 | Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3. |
Q41243369 | Sulforaphane Induced Apoptosis via Promotion of Mitochondrial Fusion and ERK1/2-Mediated 26S Proteasome Degradation of Novel Pro-survival Bim and Upregulation of Bax in Human Non-Small Cell Lung Cancer Cells |
Q37030911 | Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer |
Q34383442 | Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction |
Q35903214 | TGF-β converts apoptotic stimuli into the signal for Th9 differentiation |
Q51746852 | Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy. |
Q39575518 | Targeting the regulatory machinery of BIM for cancer therapy |
Q34685414 | The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner |
Q39870918 | The imbalance between Survivin and Bim mediates tumour growth and correlates with poor survival in patients with multiple myeloma |
Q35012398 | The pro-apoptotic protein Bim is a microRNA target in kidney progenitors |
Q38283627 | The regulation of apoptosis in kidney development: implications for nephron number and pattern? |
Q26853329 | The role of BH3-only proteins in apoptosis within the ovary |
Q37240022 | The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL). |
Q35320797 | Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim |
Q40010354 | Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2. |
Q39116492 | Triticuside A, a dietary flavonoid, inhibits proliferation of human breast cancer cells via inducing apoptosis |
Q43718895 | Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner |
Q38770788 | Tumor-suppressive activity of 1,25-dihydroxyvitamin D3 against kidney cancer cells via up-regulation of FOXO3. |
Q37290943 | Tumour cell survival signalling by the ERK1/2 pathway |
Q39037456 | Vitamin D Control of Hematopoietic Cell Differentiation and Leukemia |
Q53320503 | [Dissecting the pathways of tumour escape: " question of life and death?"]. |
Q37346002 | c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes |
Q36293209 | miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway. |
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