| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1000342485 |
| P356 | DOI | 10.1038/SJ.CDD.4400998 |
| P698 | PubMed publication ID | 11973609 |
| P50 | author | Andreas Strasser | Q38803763 |
| P2093 | author name string | Puthalakath H | |
| P2860 | cites work | PUMA induces the rapid apoptosis of colorectal cancer cells | Q24291462 |
| PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 | ||
| Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis | Q24291662 | ||
| Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors | Q24310559 | ||
| Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 | ||
| BID: a novel BH3 domain-only death agonist | Q24320091 | ||
| Bcl-2 targets the protein kinase Raf-1 to mitochondria | Q24321753 | ||
| harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L) | Q24532147 | ||
| Bim: a novel member of the Bcl-2 family that promotes apoptosis | Q24532974 | ||
| Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals | Q24555187 | ||
| Structure of Bax: coregulation of dimer formation and intracellular localization | Q27628839 | ||
| X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death | Q27733156 | ||
| Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery | Q27860586 | ||
| The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein | Q28138711 | ||
| Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
| Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD | Q28140882 | ||
| The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex | Q28141249 | ||
| Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1 | Q28142184 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors | Q39457731 | ||
| Anchorage dependence, integrins, and apoptosis | Q40754534 | ||
| Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. | Q40777275 | ||
| Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. | Q41132569 | ||
| Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death | Q42660594 | ||
| Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2. | Q42692754 | ||
| CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis | Q43594303 | ||
| A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans | Q47069275 | ||
| Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally | Q52531761 | ||
| Thymocyte apoptosis induced by p53-dependent and independent pathways | Q54242475 | ||
| DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2 | Q57338694 | ||
| Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A | Q77406620 | ||
| BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
| Tissue expression and subcellular localization of the pro-survival molecule Bcl-w | Q28203506 | ||
| Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis | Q28212224 | ||
| Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt | Q28255373 | ||
| Mechanisms and Functions of Cell Death | Q28261655 | ||
| The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9 | Q28272159 | ||
| Death Receptors: Signaling and Modulation | Q28280897 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis | Q28511080 | ||
| The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues | Q28512628 | ||
| Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis | Q28512752 | ||
| Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release | Q28567073 | ||
| Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim | Q28587387 | ||
| Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis | Q28588677 | ||
| Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis | Q28647600 | ||
| Mitochondria and apoptosis | Q29547905 | ||
| BCL-2 family members and the mitochondria in apoptosis | Q29614427 | ||
| The Bcl-2 protein family: arbiters of cell survival | Q29618158 | ||
| p53 is required for radiation-induced apoptosis in mouse thymocytes | Q29620281 | ||
| Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L). | Q30865931 | ||
| Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis | Q31577756 | ||
| Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis | Q32064384 | ||
| The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein | Q33876675 | ||
| A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes | Q33888184 | ||
| Apoptosis signaling | Q34019359 | ||
| BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
| Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2. | Q34388176 | ||
| BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak | Q35079498 | ||
| The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells | Q35745742 | ||
| Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2. | Q36368462 | ||
| Fas ligand, Bcl-2, granulocyte colony-stimulating factor, and p38 mitogen-activated protein kinase: Regulators of distinct cell death and survival pathways in granulocytes. | Q36368794 | ||
| Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1 | Q36429868 | ||
| Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L) | Q36774959 | ||
| The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene | Q38321297 | ||
| Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis | Q38326924 | ||
| P433 | issue | 5 | |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 505-512 | |
| P577 | publication date | 2002-05-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Cell Death & Differentiation | Q2943974 |
| P1476 | title | Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins | |
| P478 | volume | 9 |
| Q36547042 | (De)constructing mitochondria: what for? |
| Q28214507 | 14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax |
| Q36088695 | 15,16-Dihydrotanshinone I from the Functional Food Salvia miltiorrhiza Exhibits Anticancer Activity in Human HL-60 Leukemia Cells: in Vitro and in Vivo Studies |
| Q47810902 | A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation |
| Q34623508 | A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis |
| Q24810612 | A molecular analysis by gene expression profiling reveals Bik/NBK overexpression in sporadic breast tumor samples of Mexican females |
| Q24293188 | A novel 21-kDa cytochrome c-releasing factor is generated upon treatment of human leukemia U937 cells with geranylgeraniol |
| Q36322007 | A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells |
| Q38308288 | A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. |
| Q39558441 | A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen |
| Q28387182 | A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos |
| Q34285501 | AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF |
| Q40666435 | Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways |
| Q40644298 | Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria |
| Q40662652 | Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. |
| Q93376782 | Age-Dependent Differential Expression of Apoptotic Markers in Rat Oral Mucosa |
| Q40511785 | Alkylphosphocholine-induced glioma cell death is BCL-X(L)-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation |
| Q35567264 | Alterations in the apoptotic machinery and their potential role in anticancer drug resistance |
| Q42173208 | Alternative splicing of Bim and Erk-mediated Bim(EL) phosphorylation are dispensable for hematopoietic homeostasis in vivo. |
| Q40208980 | An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis |
| Q34630923 | Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells |
| Q41633732 | Anti-apoptotic gene therapy prolongs survival of corneal endothelial cells during storage. |
| Q28506730 | Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosis |
| Q28749134 | Apoptosis Induction by MEK Inhibition in Human Lung Cancer Cells Is Mediated by Bim |
| Q58327271 | Apoptosis and cancer |
| Q36382247 | Apoptosis and necrosis in the liver: a tale of two deaths? |
| Q36052709 | Apoptosis in cerebral ischemia: executional and regulatory signaling mechanisms |
| Q33788708 | Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells. |
| Q34732045 | Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. |
| Q40458245 | Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. |
| Q36963811 | Apoptosis regulators as targets for cancer therapy |
| Q40131183 | Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia |
| Q36017772 | Apoptosis-based therapies and drug targets |
| Q38208805 | Apoptotic cell death under hypoxia. |
| Q34051214 | Apoptotic effects of curcumin on human osteosarcoma U2OS cells |
| Q46395032 | B-cell lymphoma 2 inhibitor ABT-737 induces Beclin1- and reactive oxygen species-dependent autophagy in Adriamycin-resistant human hepatocellular carcinoma cells |
| Q39073674 | BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells |
| Q34231949 | BBC3 mediates fenretinide-induced cell death in neuroblastoma |
| Q42598140 | BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization |
| Q36445905 | BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia. |
| Q42438129 | BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells. |
| Q36419013 | BCL2 family of apoptosis-related genes: functions and clinical implications in cancer |
| Q42183839 | BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells |
| Q38779981 | BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells. |
| Q36787654 | BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells |
| Q33713980 | BH3-based fusion artificial peptide induces apoptosis and targets human colon cancer |
| Q41432640 | BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma |
| Q36017091 | BH3-only protein Bim is associated with the degree of Helicobacter pylori-induced gastritis and is localized to the mitochondria of inflammatory cells in the gastric mucosa |
| Q39907753 | BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3. |
| Q36498473 | BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection |
| Q36577830 | BH3-only protein bid participates in the Bcl-2 network in healthy liver cells |
| Q41837676 | BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. |
| Q34085370 | BH3-only proteins in apoptosis and beyond: an overview |
| Q35883875 | BH3-only proteins in apoptosis at a glance |
| Q28085220 | BH3-only proteins: a 20-year stock-take |
| Q36435312 | BH3-only proteins: integrated control point of apoptosis |
| Q35539267 | BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals |
| Q24337595 | BOK and NOXA are essential mediators of p53-dependent apoptosis |
| Q37237621 | Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members |
| Q40170925 | Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway |
| Q90149293 | Bcl-2 Proteins Regulate Mitophagy in Lipopolysaccharide-Induced Acute Lung Injury via PINK1/Parkin Signaling Pathway |
| Q47874582 | Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium. |
| Q36508817 | Bcl-2-family proteins and hematologic malignancies: history and future prospects |
| Q52576329 | Beta1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells |
| Q83728527 | Bid and Bax Are Involved in Granulosa Cell Apoptosis During Follicular Atresia in Porcine Ovaries |
| Q28473237 | Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects |
| Q37088223 | Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection. |
| Q35075545 | Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. |
| Q35737865 | Bim and Bmf in tissue homeostasis and malignant disease |
| Q34007843 | Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis. |
| Q38321058 | Bim is a direct target of a neuronal E2F-dependent apoptotic pathway. |
| Q48298601 | Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis. |
| Q33837060 | Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. |
| Q28910218 | Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets |
| Q36118310 | BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins |
| Q30540200 | Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death. |
| Q35204844 | Body language: the function of PML nuclear bodies in apoptosis regulation |
| Q39845306 | Bz-423 superoxide signals B cell apoptosis via Mcl-1, Bak, and Bax. |
| Q53880896 | CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack. |
| Q99350036 | CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage |
| Q37146087 | Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival |
| Q40191642 | Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cells |
| Q53301813 | Cancer caused by too much apoptosis--an intriguing contradiction? |
| Q36017432 | Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling |
| Q39600380 | Caspase cleavage of HER-2 releases a Bad-like cell death effector |
| Q40435136 | Caspase-dependent regulation and subcellular redistribution of the transcriptional modulator YY1 during apoptosis |
| Q38819260 | Caspase-mediated cleavage of Beclin1 inhibits autophagy and promotes apoptosis induced by S1 in human ovarian cancer SKOV3 cells. |
| Q36013981 | Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway |
| Q38971267 | Cell Signaling and Stress Responses. |
| Q44557839 | Cell biology: metabolism meets death |
| Q37211993 | Cell-nonautonomous inhibition of radiation-induced apoptosis by dynein light chain 1 in Caenorhabditis elegans |
| Q28272550 | Cell-nonautonomous regulation of C. elegans germ cell death by kri-1 |
| Q38061270 | Cellular and molecular mechanisms of mitochondrial function |
| Q28580739 | Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane |
| Q35620652 | Chemical-induced apoptosis: formation of the Apaf-1 apoptosome |
| Q41842617 | Chloroquine Promotes Apoptosis in Melanoma Cells by Inhibiting BH3 Domain–Mediated PUMA Degradation |
| Q35250940 | Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737. |
| Q53637253 | Co-ordinate but disproportionate activation of apoptotic, regenerative and inflammatory pathways characterizes the liver response to acute amebic infection |
| Q33186848 | Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability |
| Q90316772 | Combined reduction in the expression of MCL-1 and BCL-2 reduces organismal size in mice |
| Q50746648 | Conference report--at the forefront of cancer research: preclinical data highlights of annual meeting of the 95th American Association for Cancer Research; March 27-31, 2004; Orlando, Florida. |
| Q36321947 | Conformational control of Bax localization and apoptotic activity by Pro168. |
| Q36973727 | Consequences of the combined loss of BOK and BAK or BOK and BAX. |
| Q37258521 | Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis. |
| Q37277545 | Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death |
| Q40441498 | Coxiella burnetii inhibits activation of host cell apoptosis through a mechanism that involves preventing cytochrome c release from mitochondria |
| Q35947318 | Coxiella burnetii inhibits apoptosis in human THP-1 cells and monkey primary alveolar macrophages |
| Q34125207 | Crimean-Congo Hemorrhagic Fever Virus-Infected Hepatocytes Induce ER-Stress and Apoptosis Crosstalk |
| Q36774970 | Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis. |
| Q36862396 | Critical role for BIM in T cell receptor restimulation-induced death |
| Q43119941 | Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice |
| Q36594908 | Current concepts in apoptosis: the physiological suicide program revisited. |
| Q36580838 | Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model. |
| Q48297809 | Cyclin D1, cdk4, and Bim are involved in thrombin-induced apoptosis in cultured cortical neurons |
| Q39260965 | Cyclooxygenase-2 over-expression inhibits liver apoptosis induced by hyperglycemia. |
| Q24338613 | Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL |
| Q39392134 | Cytotoxic effects of the novel isoflavone, phenoxodiol, on prostate cancer cell lines |
| Q40660848 | Cytotoxicity and apoptosis of benzoquinones: redox cycling, cytochrome c release, and BAD protein expression |
| Q40250866 | DR5 and caspase-8 are dispensable in ER stress-induced apoptosis |
| Q37921609 | Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases |
| Q35828628 | Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. |
| Q35681836 | Deficiency of Pro-apoptotic Hrk Attenuates Programmed Cell Death in the Developing Murine Nervous System but Does Not Affect Bcl-x Deficiency-Induced Neuron Apoptosis |
| Q37212810 | Delayed treatment with a p53 inhibitor enhances recovery in stroke brain |
| Q47074168 | Delineation of the cell-extrinsic apoptosis pathway in the zebrafish. |
| Q38328604 | DeltaNp73 antisense activates PUMA and induces apoptosis in neuroblastoma cells |
| Q37723472 | Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf. |
| Q39592538 | Development of Small-Molecule PUMA Inhibitors for Mitigating Radiation-Induced Cell Death |
| Q37059647 | Diagnosing and exploiting cancer's addiction to blocks in apoptosis |
| Q33735056 | Differential cytokine withdrawal-induced death sensitivity of effector T cells derived from distinct human CD8+ memory subsets |
| Q34025440 | Differential roles of Epac in regulating cell death in neuronal and myocardial cells |
| Q24293924 | Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function |
| Q42087886 | Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation. |
| Q36275682 | Don't lose heart--therapeutic value of apoptosis prevention in the treatment of cardiovascular disease. |
| Q36349640 | Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein |
| Q24329159 | Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha |
| Q33270972 | E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation. |
| Q24306894 | ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL |
| Q46866934 | Effect of HA14-1 on apoptosis-regulating proteins in HeLa cells |
| Q36474396 | Effect of Helicobacter pylori infection on expression of Bcl-2 family members in gastric adenocarcinoma |
| Q92243263 | Effect of miRNA-19a antisense oligonucleotide and Ara-C on the proliferation and apoptosis of HL60 cells |
| Q39942521 | Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2. |
| Q81426352 | Endogenous association of Bim BH3-only protein with Mcl-1, Bcl-xL and Bcl-2 on mitochondria in human B cells |
| Q36594912 | Endoplasmic reticulum stress and apoptosis. |
| Q24300781 | Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53 |
| Q40269020 | Epidermal growth factor and serum activate distinct pathways to inhibit the BH3 only protein BAD in prostate carcinoma LNCaP cells |
| Q34914561 | Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. |
| Q37398578 | Epithelial cell expression of BCL-2 family proteins predicts mechanisms that regulate Helicobacter pylori-induced pathology in the mouse stomach |
| Q36526103 | Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells |
| Q39148562 | Epstein-Barr virus latent membrane protein 2A contributes to anoikis resistance through ERK activation |
| Q30408769 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. |
| Q24294552 | Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function |
| Q30484429 | Evolutionary origins of human apoptosis and genome-stability gene networks |
| Q37124747 | Expanding circle of inhibition: small-molecule inhibitors of Bcl-2 as anticancer cell and antiangiogenic agents |
| Q34271878 | Expression and transcriptional regulation of functionally distinct Bmf isoforms in B-chronic lymphocytic leukemia cells |
| Q57423395 | Expression of Pro- and Antiapoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation |
| Q36617005 | Expression of the proapoptotic protein Bid is an adverse prognostic factor for radiotherapy outcome in carcinoma of the cervix. |
| Q36710586 | Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim. |
| Q40606380 | Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover |
| Q35657414 | Fas death receptor signalling: roles of Bid and XIAP. |
| Q38780904 | FoxO1 regulates apoptosis induced by asbestos in the MT-2 human T-cell line |
| Q42183270 | Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein |
| Q33283940 | Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance. |
| Q30360720 | Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions. |
| Q47073936 | Functional characterization of the Bcl-2 gene family in the zebrafish. |
| Q53018676 | Gamma-aminobutyric acid induces tumor cells apoptosis via GABABR1·β-arrestins·JNKs signaling module |
| Q28469345 | Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics |
| Q41845080 | Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways |
| Q90405555 | Ginseng metabolite protopanaxadiol interferes with lipid metabolism and induces endoplasmic reticulum stress and p53 activation to promote cancer cell death |
| Q33688622 | Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax. |
| Q39718208 | Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis |
| Q41825247 | Growth-factor-dependent phosphorylation of Bim in mitosis. |
| Q44557881 | HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death |
| Q38793369 | HCMV activation of ERK-MAPK drives a multi-factorial response promoting the survival of infected myeloid progenitors |
| Q49813665 | HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer |
| Q47604558 | HIV: no PUMA no death? |
| Q64080453 | Heterogeneous Nuclear Ribonucleoprotein F Mediates Insulin Inhibition of Bcl2-Modifying Factor Expression and Tubulopathy in Diabetic Kidney |
| Q41098679 | High-resolution structural characterization of Noxa, an intrinsically disordered protein, by microsecond molecular dynamics simulations |
| Q24299128 | High-throughput methods to detect dimerization of Bcl-2 family proteins |
| Q79317948 | Histone H1.2 as a trigger for apoptosis |
| Q36394994 | How the Bcl-2 family of proteins interact to regulate apoptosis. |
| Q34299388 | Human Herpesvirus 8 Interferon Regulatory Factor-Mediated BH3-Only Protein Inhibition via Bid BH3-B Mimicry |
| Q22242660 | Hypoxia and defective apoptosis drive genomic instability and tumorigenesis |
| Q40454938 | Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL. |
| Q34205786 | Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons |
| Q33188401 | Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain |
| Q34192011 | Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development |
| Q36993180 | Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis |
| Q24681629 | Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway |
| Q46098736 | Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin |
| Q40596195 | Induction of p53-independent apoptosis by the BH3-only protein ITM2Bs |
| Q40499172 | Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA. |
| Q40039773 | Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells |
| Q44502162 | Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis |
| Q44526170 | Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax. |
| Q36604805 | Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors |
| Q36384554 | Intestinal mucositis: the role of the Bcl-2 family, p53 and caspases in chemotherapy-induced damage. |
| Q30389323 | Intrinsically disordered proteins in bcl-2 regulated apoptosis. |
| Q84630351 | Involvement of Bid and caspase‐2 in endoplasmic reticulum stress‐ and oxidative stress‐induced retinal ganglion cell death |
| Q33715053 | Involvement of glycoreceptors in galactoxylomannan-induced T cell death. |
| Q44593627 | Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks |
| Q47118502 | JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins |
| Q33221498 | JNK inhibitory kinase is up-regulated in retinal ganglion cells after axotomy and enhances BimEL expression level in neuronal cells |
| Q24554008 | JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis |
| Q34713366 | JNK signaling in apoptosis |
| Q58768405 | KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer |
| Q42114228 | Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cells. |
| Q36294226 | Life in the balance: how BH3-only proteins induce apoptosis. |
| Q47618625 | Lipidic pore formation by the concerted action of proapoptotic BAX and tBID. |
| Q35661658 | Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. |
| Q24530640 | Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands |
| Q37019406 | Loss of Hus1 sensitizes cells to etoposide-induced apoptosis by regulating BH3-only proteins |
| Q35641895 | Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death |
| Q33432478 | Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-XL (BCL2L1). |
| Q42497012 | Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia |
| Q33228343 | Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma. |
| Q40576914 | Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells |
| Q37425601 | MCL-1-dependent leukemia cells are more sensitive to chemotherapy than BCL-2-dependent counterparts |
| Q42413848 | MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. |
| Q35990714 | MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism |
| Q33694482 | Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK. |
| Q28756675 | Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri |
| Q36468900 | Mechanisms of cytochrome c release from mitochondria |
| Q37341018 | Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis |
| Q39143778 | Metabolic reprogramming and apoptosis sensitivity: defining the contours of a T cell response. |
| Q34158848 | Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells |
| Q39168078 | Microarray determination of Bcl-2 family protein inhibition sensitivity in breast cancer cells |
| Q36733199 | Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma |
| Q36627807 | Mitochondria in neutrophil apoptosis |
| Q36546659 | Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1. |
| Q28388183 | Mitochondrial adaptations to oxidative stress confer resistance to apoptosis in lymphoma cells |
| Q39865156 | Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak |
| Q34451522 | Mitochondrial carrier homolog 2: a clue to cracking the BCL-2 family riddle? |
| Q35120714 | Mitochondrial membrane permeabilisation by Bax/Bak |
| Q37700096 | Mitochondrial signaling in cell death via the Bcl-2 family |
| Q45437312 | Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis |
| Q33186850 | Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy |
| Q24534853 | Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite |
| Q33597533 | Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation. |
| Q40329192 | Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria |
| Q31051374 | N-cadherin mediates neuronal cell survival through Bim down-regulation |
| Q36104876 | NF-kappaB1 and c-Rel cooperate to promote the survival of TLR4-activated B cells by neutralizing Bim via distinct mechanisms |
| Q34286977 | NGF deprivation-induced gene expression: after ten years, where do we stand? |
| Q45270341 | Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway |
| Q38132359 | Non-Hodgkin's B-cell lymphoma: advances in molecular strategies targeting drug resistance |
| Q37695139 | Non-caspase proteases: triggers or amplifiers of apoptosis? |
| Q38144919 | Non-genomic events determining the sensitivity of hemopoietic malignancies to glucocorticoid-induced apoptosis |
| Q24298561 | Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells |
| Q36088654 | Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis |
| Q35804409 | Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma |
| Q46930696 | Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm |
| Q28484910 | Oncogenic kit triggers Shp2/Erk1/2 pathway to down-regulate the pro-apoptotic protein Bim and to promote apoptosis resistance in leukemic cells |
| Q33303792 | Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line |
| Q35129689 | Overview: apoptotic signaling pathways in the immune system |
| Q38094613 | Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis |
| Q39883578 | PAR bZIP-bik is a novel transcriptional pathway that mediates oxidative stress-induced apoptosis in fibroblasts |
| Q35040007 | PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes. |
| Q38295612 | PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells |
| Q36166503 | Pathways of apoptosis and importance in development. |
| Q42115619 | Pharmacological manipulation of Bcl-2 family members to control cell death |
| Q24318108 | Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32 |
| Q36892623 | Piercing the armor of hepatobiliary cancer: Bcl-2 homology domain 3 (BH3) mimetics and cell death. |
| Q21284163 | Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL |
| Q38938926 | Plant-derived protease inhibitors LC-pi (Lavatera cashmeriana) inhibit human lung cancer cell proliferation in vitro |
| Q40134376 | Poliovirus induces Bax-dependent cell death mediated by c-Jun NH2-terminal kinase |
| Q37541099 | Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury. |
| Q28573853 | Potential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemia |
| Q35149356 | Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice. |
| Q36233254 | Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death |
| Q34167987 | Prognostic impact of bim, puma, and noxa expression in human colon carcinomas. |
| Q36525099 | Prognostic impact of the expression/phosphorylation of the BH3-only proteins of the BCL-2 family in glioblastoma multiforme |
| Q37773421 | Programmed cell death of dendritic cells in immune regulation |
| Q36473311 | Prolonged expression of Puma in cholinergic amacrine cells during the development of rat retina. |
| Q39600050 | Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response |
| Q46723189 | Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. |
| Q46886447 | Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis. |
| Q42028214 | Rate and extent of protein localization is controlled by peptide-binding domain association kinetics and morphology |
| Q40615490 | Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells |
| Q75233308 | Reactive oxygen species regulate quiescent T-cell apoptosis via the BH3-only proapoptotic protein BIM |
| Q40533674 | Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways |
| Q41812910 | Regulation of Immune Responses by Spontaneous and T cell-mediated Dendritic Cell Death |
| Q35574143 | Regulation of apoptosis by Bcl‐2 family proteins |
| Q36853412 | Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering. |
| Q40561256 | Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens. |
| Q37826384 | Role of Bcl-2 family proteins and caspases in the regulation of apoptosis. |
| Q38059246 | Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy. |
| Q24306494 | Role of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4 |
| Q39047050 | Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells |
| Q79130136 | Sequence-specific Dimerization of the Transmembrane Domain of the “BH3-only” Protein BNIP3 in Membranes and Detergent |
| Q40632735 | Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions. |
| Q88657330 | Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice |
| Q40663965 | Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes |
| Q24655353 | Sp1 and p73 activate PUMA following serum starvation |
| Q33916859 | Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells |
| Q33530125 | Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases |
| Q41846014 | Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation. |
| Q36050843 | Subcellular Preconditioning of Stem Cells: Mito-Cx43 Gene Targeting is Cytoprotective Via Shift of Mitochondrial Bak and Bcl-xL Balance |
| Q50930237 | Subversion of the Bcl-2 life/death switch in cancer development and therapy. |
| Q28509136 | Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis |
| Q34561806 | Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid |
| Q50875899 | TGFbeta-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL. |
| Q40597116 | Targeting and amplification of immune killing of tumor cells by pro-Smac |
| Q36067778 | The BCL-2 protein family, BH3-mimetics and cancer therapy |
| Q36751256 | The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland. |
| Q46944717 | The BH3-only protein Puma is both necessary and sufficient for neuronal apoptosis induced by DNA damage in sympathetic neurons |
| Q24620437 | The Bcl-2 apoptotic switch in cancer development and therapy |
| Q35591695 | The Bcl-2 family: roles in cell survival and oncogenesis. |
| Q35031256 | The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions |
| Q24622720 | The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis |
| Q36223568 | The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes. |
| Q39033614 | The Interconnections between Autophagy and Integrin-Mediated Cell Adhesion |
| Q24676636 | The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells |
| Q24294754 | The Nuclear Guanine Nucleotide Exchange Factors Ect2 and Net1 Regulate RhoB-Mediated Cell Death after DNA Damage |
| Q58801228 | The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress |
| Q41878080 | The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury |
| Q42587755 | The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity |
| Q28281092 | The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia |
| Q35083049 | The essential role of evasion from cell death in cancer |
| Q35557641 | The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis. |
| Q40508757 | The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells |
| Q34205697 | The many roles of FAS receptor signaling in the immune system |
| Q37362905 | The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer |
| Q36047162 | The role of BH3-only proteins in the immune system |
| Q37566195 | The role of HRK gene in human cancer |
| Q34859478 | The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. |
| Q35091123 | The role of the Bcl-2 protein family in cancer |
| Q50736052 | The stability and anti-apoptotic function of A1 are controlled by its C terminus |
| Q24317331 | The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression |
| Q39455647 | The vaccinia virus-encoded Bcl-2 homologues do not act as direct Bax inhibitors |
| Q36764882 | Therapeutic targets in the mitochondrial apoptotic pathway |
| Q38084287 | Therapeutic targets in triple negative breast cancer |
| Q42051446 | Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1. |
| Q42638167 | Tissue transglutaminase is a multifunctional BH3-only protein |
| Q35743127 | Toxic proteins released from mitochondria in cell death |
| Q34124193 | Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells |
| Q36945203 | Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic |
| Q35674085 | Tumor necrosis factor: an apoptosis JuNKie? |
| Q37290943 | Tumour cell survival signalling by the ERK1/2 pathway |
| Q35808960 | Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease |
| Q27641770 | Unique structural features of a BCL-2 family protein CED-9 and biophysical characterization of CED-9/EGL-1 interactions |
| Q42023832 | Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection |
| Q37008257 | What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain |
| Q84222810 | ZNF689 suppresses apoptosis of hepatocellular carcinoma cells through the down-regulation of Bcl-2 family members |
| Q43098314 | c-Cbl is not required for ERK1/2-dependent degradation of BimEL. |
| Q34681377 | miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes |
| Q39480964 | miR‐92 is a key oncogenic component of the miR‐17–92 cluster in colon cancer |
| Q64379190 | p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death |
| Q24681282 | p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion |
| Q53355086 | ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation |
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