Coxiella burnetii inhibits activation of host cell apoptosis through a mechanism that involves preventing cytochrome c release from mitochondria

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Coxiella burnetii inhibits activation of host cell apoptosis through a mechanism that involves preventing cytochrome c release from mitochondria is …
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scholarly articleQ13442814

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P356DOI10.1128/IAI.00863-07
P932PMC publication ID2168311
P698PubMed publication ID17709406
P5875ResearchGate publication ID6131343

P50authorCraig R. RoyQ40064329
P2093author name stringAnja Lührmann
P2860cites workCytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeQ24311006
Q feverQ24550722
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Temporal analysis of Coxiella burnetii morphological differentiationQ37583353
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Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophilaQ39776740
In vitro susceptibility of Coxiella burnetii to antibiotics, including several quinolonesQ39828392
Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophilaQ40243451
Toxoplasma gondii inhibits ultraviolet light-induced apoptosis through multiple interactions with the mitochondrion-dependent programmed cell death pathwayQ40324192
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c releaseQ40388328
The autophagic pathway is actively modulated by phase II Coxiella burnetii to efficiently replicate in the host cell.Q40465371
Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.Q40504222
Autophagy induction favours the generation and maturation of the Coxiella-replicative vacuoles.Q40506373
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A proposed model to explain persistent infection of host cells with Coxiella burnetiiQ40808134
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Shigella flexneri induces apoptosis in infected macrophagesQ41614246
Maturation of the Coxiella burnetii parasitophorous vacuole requires bacterial protein synthesis but not replicationQ44482825
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Replication of Coxiella burnetii is inhibited in CHO K-1 cells treated with inhibitors of cholesterol metabolismQ46947191
Coxiella burnetii express type IV secretion system proteins that function similarly to components of the Legionella pneumophila Dot/Icm systemQ47725210
Turning a tiger into a house cat: using Legionella pneumophila to study Coxiella burnetiiQ47838091
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Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophagesQ73287558
BCL-2 gene family and the regulation of programmed cell deathQ77303933
Chlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteinsQ24645975
Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein familyQ24677004
Coxiella burnetii exhibits morphological change and delays phagolysosomal fusion after internalization by J774A.1 cellsQ28138558
Phagolysosomes of Coxiella burnetii-infected cell lines maintain an acidic pH during persistent infectionQ28206600
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICADQ28258328
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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell deathQ29620021
Infection of Vero cells with Coxiella burnetii phase II: relative intracellular bacterial load and distribution estimated by confocal laser scanning microscopy and morphometry.Q30635074
A translocated bacterial protein protects vascular endothelial cells from apoptosisQ33264405
The phagosome: compartment with a license to killQ33271748
Developmental biology of Coxiella burnettiiQ33601944
Q fever and Coxiella burnetii: a model for host-parasite interactionsQ33627622
Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cellsQ33716144
Nitric oxide inhibits Coxiella burnetii replication and parasitophorous vacuole maturationQ34129925
Coxiella burnetii localizes in a Rab7-labeled compartment with autophagic characteristicsQ34132094
Chromosomal DNA deletions explain phenotypic characteristics of two antigenic variants, phase II and RSA 514 (crazy), of the Coxiella burnetii nine mile strainQ34258745
Inhibition of apoptosis by intracellular protozoan parasitesQ34373696
BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death.Q34598392
Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetiiQ34611714
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteinsQ34612753
Independent contribution of three different pathways to ultraviolet-B-induced apoptosisQ34816028
Apoptosomes: engines for caspase activationQ35021215
Differential interaction with endocytic and exocytic pathways distinguish parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatisQ35472930
Chlamydia and apoptosis: life and death decisions of an intracellular pathogen.Q35892057
Coxiella burnetii inhibits apoptosis in human THP-1 cells and monkey primary alveolar macrophagesQ35947318
Micro-managing the executioner: pathogen targeting of mitochondriaQ36024106
NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.Q36228869
Life in the balance: how BH3-only proteins induce apoptosis.Q36294226
Lysosomal response of a murine macrophage-like cell line persistently infected with Coxiella burnetii.Q36348953
How the Bcl-2 family of proteins interact to regulate apoptosis.Q36394994
Caspases at the crossroads of immune-cell life and deathQ36430147
NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infectionQ36478121
Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector proteinQ36827596
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
Coxiella burnetiiQ133971
P304page(s)5282-5289
P577publication date2007-08-20
P1433published inInfection and ImmunityQ6029193
P1476titleCoxiella burnetii inhibits activation of host cell apoptosis through a mechanism that involves preventing cytochrome c release from mitochondria
P478volume75