scholarly article | Q13442814 |
P2093 | author name string | W S Dalton | |
L A Hazlehurst | |||
R F Argilagos | |||
P2860 | cites work | Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 |
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex | Q28141249 | ||
Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim | Q28201672 | ||
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells | Q28277030 | ||
Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells | Q28505374 | ||
G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression | Q33836907 | ||
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo | Q34503877 | ||
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins | Q34612753 | ||
Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways | Q34729632 | ||
Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells. | Q40462629 | ||
Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors | Q40540288 | ||
Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover | Q40606380 | ||
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. | Q40626751 | ||
Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation | Q40789146 | ||
BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. | Q41837676 | ||
Integrin-mediated activation of MEK and mitogen-activated protein kinase is independent of Ras [corrected]. | Q42810800 | ||
Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells | Q43722430 | ||
Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells | Q43727826 | ||
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis | Q44502162 | ||
Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds. | Q46757499 | ||
Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). | Q52540929 | ||
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells. | Q52826677 | ||
Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines. | Q53978532 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | leukemia | Q29496 |
drug resistance | Q12147416 | ||
P304 | page(s) | 269-275 | |
P577 | publication date | 2007-01-01 | |
P1433 | published in | British Journal of Haematology | Q4970200 |
P1476 | title | Beta1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells. | |
P478 | volume | 136 |
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