| scholarly article | Q13442814 |
| P50 | author | Ronald A. DePinho | Q7364619 |
| Yun-Cai Liu | Q58812903 | ||
| P2093 | author name string | Yohsuke Harada | |
| Ji-Hye Paik | |||
| Chris Elly | |||
| Ge Ying | |||
| Yasuyo Harada | |||
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| FOXP3 controls regulatory T cell function through cooperation with NFAT | Q24298179 | ||
| Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1 | Q24300625 | ||
| Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins | Q24310048 | ||
| Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation | Q24550768 | ||
| Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3 | Q24672849 | ||
| Control of regulatory T cell development by the transcription factor Foxp3 | Q27860489 | ||
| Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Q27860714 | ||
| Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1 | Q28276788 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis | Q28285131 | ||
| The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1 | Q28591890 | ||
| Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a | Q28592736 | ||
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| Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells | Q33591090 | ||
| Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. | Q33797113 | ||
| Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells. | Q34088521 | ||
| Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer | Q34729938 | ||
| Immunity by ubiquitylation: a reversible process of modification | Q36328809 | ||
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| T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. | Q36693820 | ||
| An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance | Q37217188 | ||
| Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells | Q37394198 | ||
| Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1. | Q37394376 | ||
| Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo | Q40327455 | ||
| Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
| Molecular mechanisms underlying FOXP3 induction in human T cells | Q42491664 | ||
| Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells | Q42538765 | ||
| The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment | Q42593305 | ||
| Runx proteins regulate Foxp3 expression | Q42594337 | ||
| Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction. | Q45179048 | ||
| Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells | Q45345520 | ||
| Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
| Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a | Q80444906 | ||
| What turns on Foxp3? | Q80513315 | ||
| Inducing and expanding regulatory T cell populations by foreign antigen | Q81392563 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1381-1391 | |
| P577 | publication date | 2010-05-03 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells | |
| P478 | volume | 207 |
| Q38872469 | A Bacterial Artificial Chromosome Reporter System for Expression of the Human FOXP3 Gene in Mouse Regulatory T-Cells |
| Q90575658 | A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma |
| Q33828647 | Analysis of the transcriptional program of developing induced regulatory T cells |
| Q36250847 | Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1. |
| Q38034269 | At the crossroad of T cells, adipose tissue, and diabetes |
| Q34700458 | Becoming self-aware: the thymic education of regulatory T cells. |
| Q50958644 | Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells. |
| Q35572346 | Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720. |
| Q35735738 | Cbl-b: Roles in T Cell Tolerance, Proallergic T Cell Development, and Cancer Immunity |
| Q26853475 | Cellular and molecular determinants for the development of natural and induced regulatory T cells |
| Q46155473 | Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo. |
| Q28592480 | Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells |
| Q89777242 | Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T cells |
| Q35138124 | Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo |
| Q91868611 | Differential Control of iNKT Cell Effector Lineage Differentiation by the Forkhead Box Protein O1 (Foxo1) Transcription Factor |
| Q36346401 | Differential effect of DJ-1/PARK7 on development of natural and induced regulatory T cells |
| Q41864874 | Does the PI3K pathway promote or antagonize regulatory T cell development and function? |
| Q33953086 | E3 ubiquitin ligase Cbl-b in innate and adaptive immunity |
| Q37672304 | E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation |
| Q30253022 | Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells |
| Q47805371 | Experimental evidences for miR-30b as a negative regulator of FOXO3 upregulated by kynurenine |
| Q33949282 | Extra-thymically induced regulatory T cells: do they have potential in disease prevention? |
| Q26853741 | FOXO transcription factors throughout T cell biology |
| Q33594004 | FOXO transcription factors: their clinical significance and regulation. |
| Q34167902 | FOXO3 regulates CD8 T cell memory by T cell-intrinsic mechanisms. |
| Q36349658 | FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function |
| Q47224295 | FOXOs in Cancer Immunity: Knowns and Unknowns |
| Q38074598 | FOXOs: signalling integrators for homeostasis maintenance |
| Q38172563 | Forkhead box P3: the peacekeeper of the immune system. |
| Q64447846 | Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis |
| Q33774905 | Foxo transcription factors control regulatory T cell development and function |
| Q52569779 | Foxo transcription factors in T cell biology and tumor immunity. |
| Q26829456 | Foxo3a: an integrator of immune dysfunction during HIV infection |
| Q34645402 | Foxo: in command of T lymphocyte homeostasis and tolerance |
| Q35981383 | Fyn promotes Th17 differentiation by regulating the kinetics of RORγt and Foxp3 expression |
| Q82046024 | Gene profile analysis of CD8+ ILT3-Fc induced T suppressor cells |
| Q36938160 | Generation and function of induced regulatory T cells |
| Q50097667 | Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood. |
| Q37215636 | Heligmosomoides polygyrus bakeri infection activates colonic Foxp3+ T cells enhancing their capacity to prevent colitis |
| Q34631825 | How tolerogenic dendritic cells induce regulatory T cells |
| Q37642581 | Human IDO-competent, long-lived immunoregulatory dendritic cells induced by intracellular pathogen, and their fate in humanized mice |
| Q37215023 | Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway |
| Q47774246 | Immune Regulation by Ubiquitin Tagging as Checkpoint Code. |
| Q37626146 | Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells |
| Q95271900 | Inducers, Attractors and Modulators of CD4+ Treg Cells in Non-Small-Cell Lung Cancer |
| Q38526844 | Integrated Akt/PKB signaling in immunomodulation and its potential role in cancer immunotherapy |
| Q34098180 | Interleukin-21 promotes germinal center reaction by skewing the follicular regulatory T cell to follicular helper T cell balance in autoimmune BXD2 mice |
| Q33853966 | KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production |
| Q88294430 | KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity |
| Q26773901 | Long live FOXO: unraveling the role of FOXO proteins in aging and longevity |
| Q35673283 | Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells |
| Q37974991 | Lymphocyte signaling: regulation of FoxO transcription factors by microRNAs |
| Q37878290 | Mechanisms that regulate peripheral immune responses to control organ-specific autoimmunity |
| Q26749842 | Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation |
| Q28384629 | Mitochondria and FOXO3: breath or die |
| Q83225642 | Modulating FOXO3 transcriptional activity by small, DBD-binding molecules |
| Q38393275 | Modulation of Immune Cell Functions by the E3 Ligase Cbl-b. |
| Q89965514 | Molecular Mechanisms Controlling Foxp3 Expression in Health and Autoimmunity: From Epigenetic to Post-translational Regulation |
| Q37952092 | Molecular mechanisms underlying the regulation and functional plasticity of FOXP3(+) regulatory T cells |
| Q91797826 | Molecular networks of FOXP family: dual biologic functions, interplay with other molecules and clinical implications in cancer progression |
| Q92071841 | Mucosal Immunity and the FOXO1 Transcription Factors |
| Q37011956 | Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways |
| Q27014799 | Nature and nurture in Foxp3(+) regulatory T cell development, stability, and function |
| Q37549928 | Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy. |
| Q50858344 | New roles for cyclin-dependent kinases in T cell biology: linking cell division and differentiation. |
| Q39100271 | Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner |
| Q30544655 | Novel Foxo1-dependent transcriptional programs control T(reg) cell function |
| Q41927540 | Nuclear accumulation of β-catenin and forkhead box O3a in colon cancer: Dangerous liaison |
| Q34100538 | Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment |
| Q33979859 | PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors |
| Q36516932 | PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances |
| Q48162457 | PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells. |
| Q64062347 | Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7 |
| Q34285649 | Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. |
| Q38614123 | Pharmacologic targeting of regulatory T cells for solid organ transplantation: current and future prospects |
| Q36084223 | Polar opposites: Erk direction of CD4 T cell subsets |
| Q38206224 | Progesterone and its downstream molecules as blastocyst implantation essential factors |
| Q38288135 | Prognosis in autoimmune and infectious disease: new insights from genetics. |
| Q41613842 | Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway |
| Q28115646 | Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes |
| Q95299218 | Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells |
| Q64081455 | Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation |
| Q24626339 | Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells |
| Q36157753 | Regulation and function of mTOR signalling in T cell fate decisions |
| Q48668293 | Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation |
| Q34177949 | Regulatory T cells and Foxp3 |
| Q91297827 | Regulatory T cells in cancer immunosuppression - implications for anticancer therapy |
| Q26827787 | Regulatory T cells: Mechanisms of suppression and impairment in autoimmune liver disease |
| Q29620731 | Regulatory T cells: mechanisms of differentiation and function |
| Q21285001 | Releasing the brake: targeting Cbl-b to enhance lymphocyte effector functions |
| Q92152691 | Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells |
| Q36893499 | Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation |
| Q38095574 | Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation. |
| Q37033632 | SHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complex |
| Q36104873 | Salt Accelerates Allograft Rejection through Serum- and Glucocorticoid-Regulated Kinase-1-Dependent Inhibition of Regulatory T Cells |
| Q37982939 | Selection of regulatory T cells in the thymus |
| Q36603536 | Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells |
| Q30356570 | Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells. |
| Q38644779 | Stabilizing human regulatory T cells for tolerance inducing immunotherapy |
| Q92863003 | T Cell-Specific Overexpression of Acid Sphingomyelinase Results in Elevated T Cell Activation and Reduced Parasitemia During Plasmodium yoelii Infection |
| Q36986111 | T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells |
| Q26749508 | T cell receptor signalling in the control of regulatory T cell differentiation and function |
| Q36711920 | T(reg) stability: to be or not to be. |
| Q54121475 | T-Cell-Specific Loss of the PI-3-Kinase p110α Catalytic Subunit Results in Enhanced Cytokine Production and Antitumor Response. |
| Q41897840 | TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2. |
| Q45356807 | TRAF6 directs commitment to regulatory T cells in thymocytes |
| Q37384026 | TSC1 regulates the balance between effector and regulatory T cells |
| Q36372616 | Targeting Treg signaling for the treatment of autoimmune diseases |
| Q34901817 | The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells |
| Q37032005 | The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression |
| Q34443724 | The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067. |
| Q28742303 | The PI3K p110δ regulates expression of CD38 on regulatory T cells |
| Q94596546 | The Regulatory Effects of mTOR Complexes in the Differentiation and Function of CD4+ T Cell Subsets |
| Q50069736 | The Role of Forkhead Box 1 (FOXO1) in the Immune System: Dendritic Cells, T Cells, B Cells, and Hematopoietic Stem Cells |
| Q38035848 | The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function |
| Q43686523 | The TGF-β-Smad3 pathway inhibits CD28-dependent cell growth and proliferation of CD4 T cells |
| Q33570917 | The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses. |
| Q26830354 | The mTOR pathway and integrating immune regulation |
| Q37792556 | The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism |
| Q35490792 | The molecular mechanisms of Foxp3 gene regulation. |
| Q33958655 | The potential mechanistic link between allergy and obesity development and infant formula feeding |
| Q38129079 | The role of FOXP3 in regulating immune responses |
| Q38124036 | The role of ubiquitin ligases in the control of organ specific autoimmunity |
| Q35115481 | The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation |
| Q34527281 | Therapeutic opportunities for manipulating T(Reg) cells in autoimmunity and cancer |
| Q47749841 | Thymic function in the regulation of T cells, and molecular mechanisms underlying the modulation of cytokines and stress signaling (Review). |
| Q36959215 | Thymic versus induced regulatory T cells - who regulates the regulators? |
| Q35857403 | Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation |
| Q38135555 | Transcriptional control of regulatory T cell development and function |
| Q50420265 | Transcriptional regulation and development of regulatory T cells. |
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| Q26775820 | Translational utility of experimental autoimmune encephalomyelitis: recent developments |
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| Q51737095 | [Rapamycin affect the apoptosis of splenic CD4+CD25+ regulatory T cells of mouse severe aplastic anemia model]. |
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| Q39230080 | mTORC2-PKBα/Akt1 Serine 473 phosphorylation axis is essential for regulation of FOXP3 Stability by chemokine CCL3 in psoriasis |
| Q89495765 | miR-155 promotes fibroblast-like synoviocyte proliferation and inflammatory cytokine secretion in rheumatoid arthritis by targeting FOXO3a |
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